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收藏Gain of chromosome 17 is an early genetic abnormality in neuroblastoma with PPM1D emerging as a strong candidate oncogene driving tumor progression染色体17的获得是神经母细胞瘤中的一种早期遗传异常，其中PPM1D正作为一个强候选癌基因出现，驱动肿瘤进展。
Milosevic, Jelena; Fransson, Susanne; Svensson, Johanna; Otte, Jorg; Olsen, Thale K.; Sveinbjornsson, Baldur; Hertwig, Falk; Bartenhagen, Christoph; Abel, Frida; Reinsbach, Susanne E.; Djos, Anna; Javanmardi, Niloufar; Shi, Yao; Hehir-Kwa, Jane Y.; Mensenkamp, Arjen; Tytgat, Godelieve AM.; Holmberg, Johan; Molenaar, Jan J.; Jongmans, Marjolijn; Fischer, Matthias; Baryawno, Ninib; Gisselsson, David; Martinsson, Tommy; Kogner, Per; Johnsen, John Inge 分享 收藏 LTX-315 triggers anticancer immunity by inducing MyD88-dependent maturation of dendritic cellsLTX-315通过诱导树突状细胞的MyD88-dependent成熟来触发抗癌免疫Li, Xiao-Qing; Yamazaki, Takahiro; He, Tianzhen; Alam, Md Masud; Liu, Jia; Trivett, Anna L.; Sveinbjornsson, Baldur; Rekdal, Oystein; Galluzzi, Lorenzo; Oppenheim, Joost J.; Yang, De 分享 收藏 LTX-315 and adoptive cell therapy using tumor-infiltrating lymphocytes generate tumor specific T cells in patients with metastatic soft tissue sarcoma使用肿瘤浸润淋巴细胞的LTX-315和过继细胞疗法可在转移性软组织肉瘤患者中产生肿瘤特异性T细胞Nielsen, Morten; Monberg, Tine; Sundvold, Vibeke; Albieri, Benedetta; Hovgaard, Dorrit; Petersen, Michael Mork; Krarup-Hansen, Anders; Met, Oezcan; Camilio, Ketil; Clancy, Trevor; Stratford, Richard; Sveinbjornsson, Baldur; Rekdal, Oystein; Junker, Niels; Svane, Inge Marie 分享 收藏 分享 收藏 Intratumoral injection of LTX-315 in combination with pembrolizumab in patients with advanced melanoma refractory to prior PD-1/PD-L1 therapy: Interim results from the ATLAS-IT-05 trialDalle, S.; Marron, T. U.; Robert, C.; Aljabri, B.; Nyakas, M. S.; Slot, K. Bruins; Sundvold, V.; Rekdal, O.; Sveinbjornsson, B.; Currie, G. 分享 收藏 LTX-315-enabled, radiotherapy-boosted immunotherapeutic control of breast cancer by NK cellsLTX-315-enabled，放疗促进的NK细胞对乳腺癌的免疫治疗控制Yamazaki, Takahiro; Wennerberg, Erik; Hensler, Michal; Buque, Aitziber; Kraynak, Jeffrey; Fucikova, Jitka; Zhou, Xi Kathy; Sveinbjornsson, Baldur; Rekdal, Oystein; Demaria, Sandra; Galluzzi, Lorenzo 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 A phase I study of the oncolytic peptide LTX-315 generatesde novoT-cell responses and clinical benefit in patients with advanced sarcomaBaaurain, Jean-Francois; Jungels, Christiane; Kristeleit, Rebecca S.; Jossang, Dag E.; Jebsen, Nina L.; Rekdal, Oystein; Sveinbjornsson, Baldur; Gjerstad, Vibeke S.; Brunsvig, Paal; Galon, Jerome; Hermitte, Fabienne; Patel, Hamina 分享 收藏 A Phase I study of the oncolytic peptide LTX-315 generates de novo T-cell responses and clinical benefit in patients with advanced melanomaMarabelle, Aurelien; Baurain, Jean-Francois; Awada, Ahmad; Kristeleit, Rebbecca S.; Loirat, Delphine; Jossang, Dag E.; Jebsen, Nina L.; Sveinbjornsson, Baldur; Rekdal, Oystein; Gjerstad, Vibeke S.; Brunsvig, Paal; Galon, Jerome; Hermitte, Fabienne; Patel, Hamina; Spicer, James 分享 收藏 分享 收藏 分享 收藏 Tumor lysis with LTX-401 creates anticancer immunityXie, Wei; Mondragon, Laura; Mauseth, Brynjar; Wang, Yan; Pol, Jonathan; Levesque, Sarah; Zhou, Heng; Yamazaki, Takahiro; Eksteen, Johannes J.; Zitvogel, Laurence; Sveinbjornsson, Baldur; Rekdal, Oystein; Kepp, Oliver; Kroemer, Guido 分享 收藏 分享 收藏 Inhibitors of ribosome biogenesis repress the growth of MYCN-amplified neuroblastomaHald, Oyvind H.; Olsen, Lotte; Gallo-Oller, Gabriel; Elfman, Lotta Helena Maria; Lokke, Cecilie; Kogner, Per; Sveinbjornsson, Baldur; Flaegstad, Trond; Johnsen, John Inge; Einvik, Christer 分享 收藏 Oncolysis with DTT-205 and DTT-304 generates immunological memory in cured animalsZhou, Heng; Mondragon, Laura; Xie, Wei; Mauseth, Brynjar; Leduc, Marion; Sauvat, Allan; Gomes-da-Silva, Ligia C.; Forveille, Sabrina; Iribarren, Kristina; Souquere, Sylvie; Bezu, Lucillia; Liu, Peng; Zhao, Liwei; Zitvogel, Laurence; Sveinbjornsson, Baldur; Eksteen, J. Johannes; Rekdal, Oystein; Kepp, Oliver; Kroemer, Guido 分享 收藏 
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