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M

Michele Maio

University of Siena
H指数:99
被引数:8.4万

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The conformation-selective PI3Kδ inhibitor roginolisib in patients with advanced or metastatic cancer, including metastatic uveal melanoma: first-in-human clinical trial

在晚期或转移性癌症患者中具有构象选择性的PI3Kδ抑制剂roginolisib的临床试验：首次人体试验，包括转移性葡萄膜黑色素瘤

Nature Communications
IF15.7
2026-10-090
OAAI
Anna Maria Di Giacomo; Matteo Simonelli; Agnese Losurdo; Pavlina Spiliopoulou; Vincenzo D’Alonzo; Giovanni Amato; Monica Valente; Hugo Barcenilla; Anette Johnsson; Laura Gonzalez; Ziyang Tan; Lakshmikanth Tadepally; Petter Brodin; Michael Lahn; Giusy Di Conza; Rebeca Zorrilla; Lars van der Veen; Alessio Bevilacqua; Paramjit Kaur; Tracey Hammett; Marco Durini; Andrea Corsi; Nikhil Sindhwani; Mariaelena Occhipinti; Robert Snijder; Ayad Abdul-Ahad; Aniko Meijer; Umberto Postiglione; Gregory Price; Gillian Hopton; Emily Wood; Vincent Vuaroqueaux; Anne-Lise Peille; Jill Graham; Ming Poi; David Spetzler; Carmelo Carlo-Stella; Armando Santoro; Thomas R. Jeffry Evans; Michele Maio
Transposable elements and homotypic niches drive immune dynamics and resistance in melanoma epigenetic-based immunotherapy

转座元件和同型微环境驱动黑色素瘤表观遗传基础免疫治疗的免疫动态和抗性

Science Advances
IF12.5
2026-08-070
OA
Erika Ciervo; Francesco Ceccarelli; Anna Maria Di Giacomo; Piera Grisolia; Alessia Covre; Zein Mersini Besharat; Antonio De Falco; Francesca Pia Caruso; Luigi Laezza; Luigi Ferraro; Gloria Mas Martin; Daniel Bilbao; Sion Williams; Benjamin Currall; Maria Fortunata Lofiego; Tommaso Sani; Elisabetta Ferretti; Yan Guo; Sean B. Holden; Ines Simeone; Roberta Mortarini; Andrea Anichini; Michele Maio; Teresa Maria Rosaria Noviello; Michele Ceccarelli
Circulating EV-microRNAs are dynamic biomarkers of resistance to therapeutic immunomodulation in metastatic melanoma

循环EV-miRNA是转移性黑色素瘤对治疗性免疫调节抵抗的动态生物标志物

Communications Medicine
IF6.3
2026-05-080
OAAI
Elena Splendiani; Zein Mersini Besharat; Claudia Sabato; Teresa Maria Rosaria Noviello; Maria Fortunata Lofiego; Vincenzo D’Alonzo; Monica Valente; Laura Solmonese; Alessia Covre; Sandra Coral; Francesca Pia Caruso; Tanja Milena Autilio; Ines Simeone; Agnese Po; Anna Citarella; Giuseppina Catanzaro; Roberta Mortarini; Andrea Anichini; Michele Maio; Michele Ceccarelli; Anna Maria Di Giacomo; Elisabetta Ferretti
Neoadjuvant Intralesional Targeted Immunocytokines (Daromun) in Stage III Melanoma.

新辅助病灶内靶向免疫细胞因子（Daromun）在III期黑色素瘤中的应用。

Annals of Oncology
IF65.4
2025-07-070
PREAI
K.C. Kähler; J.C. Hassel; M. Ziemer; P. Rutkowski; F. Meier; L. Flatz; C. Gaudy-Marqueste; L. Zimmer; M. Santinami; F. Russano; I. von Wasielewski; T.K. Eigentler; M. Maio; I. Zalaudek; S. Haferkamp; P. Quaglino; J. Welzel; C. Röcken; A. Enk; J.-C. Simon; T. Świtaj; M. Garzarolli; T. Amaral; N. Malissen; E. Livingstone; G. Elia; A. Covelli; K. Lorizzo; D. Neri; S. Mulatto; A. Parca; B. Pizzichi; P.A. Ascierto; C. Garbe; C. Robert; D. Schadendorf; A. Hauschild
Pembrolizumab in microsatellite-instability-high and mismatch-repair-deficient advanced solid tumors: updated results of the KEYNOTE-158 trial

帕博利珠单抗在微卫星高度不稳定和错配修复缺陷型晚期实体瘤中的研究：KEYNOTE-158试验的更新结果

NATURE CANCER
IF28.5
2025-02-200
PRE
Marabelle, Aurelien; O'Malley, David M.; Hendifar, Andrew E.; Ascierto, Paolo A.; Motola-Kuba, Daniel; Penel, Nicolas; Cassier, Philippe A.; Bariani, Giovanni; De Jesus-Acosta, Ana; Doi, Toshihiko; Longo, Federico; Miller, Wilson H.; Oh, Do-Youn; Gottfried, Maya; Yao, Lili; Jin, Fan; Gozman, Alexander; Maio, Michele
DNA methylation status classifies pleural mesothelioma cells according to their immune profile: implication for precision epigenetic therapy

DNA甲基化状态根据其免疫表型对胸膜间皮瘤细胞进行分类：对精准表观遗传治疗的启示

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
IF12.8
2025-02-180
OA
Lofiego, Maria Fortunata; Tufano, Rossella; Bello, Emma; Solmonese, Laura; Marzani, Francesco; Piazzini, Francesca; Celesti, Fabrizio; Caruso, Francesca Pia; Noviello, Teresa Maria Rosaria; Mortarini, Roberta; Anichini, Andrea; Ceccarelli, Michele; Calabro, Luana; Maio, Michele; Coral, Sandra; Di Giacomo, Anna Maria; Covre, Alessia; EPigenetic Immune-Oncology Consortium Airc EPICA Investigators
Pembrolizumab in microsatellite instability-high/mismatch repair deficient (MSI-H/dMMR) and non-MSI-H/non-dMMR advanced endometrial cancer: Phase 2 KEYNOTE-158 study results

帕博利珠单抗在微卫星高度不稳定/错配修复缺陷（MSI-H/dMMR）和非微卫星高度不稳定/非错配修复缺陷（non-MSI-H/non-dMMR）晚期子宫内膜癌中的疗效：KEYNOTE-158研究II期结果

gynecologic oncology
IF4.1
2025-02-012
PRE
O'Malley, David M.; Bariani, Giovani M.; Cassier, Philippe A.; Marabelle, Aurelien; Hansen, Aaron R.; Acosta, Ana De Jesus; Miller Jr, Wilson H.; Safra, Tamar; Italiano, Antoine; Mileshkin, Linda; Yao, Lili; Gozma, Alexander; Jin, Fan; Maio, Michele
Pembrolizumab for the First-Line Treatment of Recurrent Locally Advanced or Metastatic Merkel Cell Carcinoma: Results from the Single-Arm, Open-Label, Phase III KEYNOTE-913 Study
AMERICAN JOURNAL OF CLINICAL DERMATOLOGY
IF8.8
2024-10-080
OAAI
Mortier, Laurent; Villabona, Lisa; Lawrence, Ben; Arance, Ana; Butler, Marcus O.; Beylot-Barry, Marie; Saiag, Philippe; Samimi, Mahtab; Ascierto, Paolo A.; Spada, Francesca; De Pontville, Michel; Maio, Michele; Berrocal, Alfonso; Espinosa, Enrique; Capdevila, Jaume; Levin, Max; Das, Debasmita; Krepler, Clemens; Grebennik, Dmitri; Chiarion-Sileni, Vanna
Nivolumab plus relatlimab vs nivolumab in previously untreated metastatic or unresectable melanoma: 3-year subgroup analyses from RELATIVITY-047

Nivolumab联合relatlimab与nivolumab单药治疗既往未治疗的转移性或不可切除性黑色素瘤：RELATIVITY-047研究的3年亚组分析

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Schadendorf, D.; Tawbi, H. A.; Hodi, F. S.; Lipson, E. J.; Ascierto, P. A.; Medina Soto, F. A.; Maio, M.; Hernberg, M.; Mackiewicz, J.; Prey, S.; Mujika Eizmendi, M. K.; Atkinson, V. G.; Hassel, J. C.; Cinat, G.; Keidel, S.; Rodriguez, S.; Wang, P. T.; Dolfi, S.; Long, G. V.
Nivolumab plus ipilimumab in melanoma patients with asymptomatic brain metastases: 7-year outcomes and quality of life from the multicenter phase III NIBIT-M2 trial (vol 199, 113531, 2024)
EUROPEAN JOURNAL OF CANCER
IF7.1
2024-05-010
PRE
Di Giacomo, Anna Maria; Chiarion-Sileni, Vanna; Del Vecchio, Michele; Ferrucci, Pier Francesco; Guida, Michele; Quaglino, Pietro; Guidoboni, Massimo; Marchetti, Paolo; Simonetti, Elena; Santangelo, Federica; Amato, Giovanni; Covre, Alessia; Camerini, Roberto; Valente, Monica; Mandala, Mario; Giannarelli, Diana; Calabro, Luana; Maio, Michele
Results from KEYNOTE-B99: Phase 2 study of first-line (1L) pembrolizumab (pembro) plus investigational agents and chemotherapy (chemo) for extensive-stage small-cell lung cancer (ES-SCLC)
CANCER RESEARCH
IF16.6
2024-04-050
PRE
Rodriguez-Abreu, Delvys; Hochmair, Maximillian; Cho, Byoung Chul; Csoszi, Tibor; Kutiel, Talia Shentzer; Mueller, Veronika; Ahn, Myung-Ju; Kowalski, Dariusz; Maio, Michele; Moiseyenko, Vladimir; Navarro, Alejandro; Niu, Jianxin; Fung, Andrea S.; Lips, Carolin; Zhou, Heng; Zhao, Bin; Lara-Guerra, Humberto; Peled, Nir

研究方向

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P
Paolo A. Ascierto
H 指数:126论文数:1,662被引数:10.9万
A
Anna Maria Di Giacomo
H 指数:51论文数:365被引数:1.4万
A
Alessia Covre
H 指数:26论文数:105被引数:2,895
L
Luana Calabrò
H 指数:40论文数:163被引数:6,874
S
Sandra Coral
H 指数:30论文数:95被引数:3,120
M
Maresa Altomonte
H 指数:41论文数:124被引数:5,789
L
Luca Sigalotti
H 指数:32论文数:94被引数:3,575
D
Dirk Schadendorf
H 指数:182论文数:2,387被引数:22.2万
F
Francesca Colizzi
H 指数:26论文数:59被引数:2,502
M
Mario Mandalà
H 指数:78论文数:519被引数:3.9万