未登录 A phase Ib/II, open-label, multicenter, randomized umbrella study evaluating the combination of atezolizumab with sacituzumab govitecan in patients with locally advanced or metastatic urothelial carcinoma and previously treated with a platinum-based treatment regimen (MORPHEUS-Urothelial Carcinoma) 一项Ib/II期、开放标签、多中心、随机伞式研究，评估阿替利珠单抗与萨喜妥珠单抗戈维他胺联用对既往接受过铂类治疗方案治疗的局部晚期或转移性尿路上皮癌患者的疗效（MORPHEUS-Urothelial Carcinoma） Shin, S. J.; Lee, J. L.; Powles, T.; Martin-Liberal, J.; Morales-Barrera, R.; Drakaki, A.; Friedlander, T.; Joly, F.; Shah, S. A.; Vuky, J.; Ianculescu, I.; Michielin, F.; Gan, X.; Bamias, A. 分享 收藏
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DISSECTING THE TUMOR MICROENVIRONMENT OF ADVANCED UROTHELIAL CARCINOMA PRE AND POST ENFORTUMAB VEDOTIN ± PEMBROLIZUMAB 解析恩沃利单抗 vedotin ± 帕博利珠单抗治疗前后的晚期尿路上皮癌肿瘤微环境 Raizenne, Brendan Lapointe; Nechiporuk, Tamilla; Ding, Cornelia; Dias, Mikhail; Yuxin, Yang; Chou, Jonathan; Friedlander, Terence; Porten, Sima; Meng, Maxwell; Quigley, David; Koshkin, Vadim; Huang, Franklin; Chu, Carissa 分享 收藏
CD46 AS A THERANOSTIC TARGET IN BLADDER CANCER: EXPRESSION PROFILING AND PRE-CLINICAL VALIDATION OF [89ZR]ZR-DFO-YS5 PET IN BLADDER CANCER CD46作为膀胱癌的诊疗靶点：表达谱分析及[89Zr]Zr-DFO-YS5 PET在膀胱癌中的临床前验证 Kornberg, Zachary Thomas; Raveendran, Athira; Delavan, Henry M.; Dougherty, William; Saxena, Shivani; Nechiporuk, Tamilla; Bidlingmaier, Scott; Wang, Chunyue; Greenland, Nancy; Friedlander, Terence W.; Porten, Sima P.; Liu, Bin; Chu, Carissa E.; Flavell, Robert R.; Chou, Jonathan 分享 收藏
EXAMINING THE IMPACT OF TGF-B ACTIVITY ON FIBROBLAST INFILTRATION AND IMMUNE EXCLUSION IN MUSCLE-INVASIVE BLADDER CANCER 探讨TGF-B活性对肌肉浸润性膀胱癌中成纤维细胞浸润和免疫排斥的影响 Gupta, Shilpa; De Jong, Joep J.; Alshalalfa, Mohammed; Chou, Jonathan; Koshkin, Vadim; Friedlander, Terence W.; Oh, David; Chu, Carissa E.; Mar, Nataliya; Sasse, Alexander; Wong, Anthony; Proudfoot, James A.; Davicioni, Elai; Seyedin, Steven Neema 分享 收藏
Study EV-103 dose escalation/cohort A (DE/A): 5y follow-up of first-line (1L) enfortumab vedotin (EV) plus pembrolizumab (P) in cisplatin (CIS)-ineligible locally advanced or metastatic urothelial carcinoma (la/mUC) 研究EV-103剂量递增/队列A（DE/A）：在不可接受顺铂治疗的局部晚期或转移性尿路上皮癌（la/mUC）中，恩沃利单抗偶联物（EV）联合帕博利珠单抗（P）的一线（1L）5年随访研究 Rosenberg, J. E.; Petrylak, D. P.; Flaig, T.; Hoimes, C. J.; Gupta, S.; O'Donnell, P. H.; Mar, N.; Friedlander, T.; Tagawa, S. T.; Bilen, M. A.; Brown, J. R.; McKay, R. R.; Merchan, J. R.; Srinivas, S.; Shetty, A.; Homet Moreno, B.; Davis, G.; Wirtz, H.; Zhu, Y.; Milowsky, M. I. 分享 收藏
Modulating the PPARγ pathway to augment NECTIN4-targeting chimeric antigen receptor (CAR) T cell therapy Chang, Kevin; Delavan, Henry M.; Zhu, Jun; Kasap, Corynn; Yip, Elizabeth; Lodha, Roshan; Liao, Sheng-You; Porten, Sima; Friedlander, Terence; Koshkin, Vadim; Feng, Felix; Wiita, Arun; Lee, John; Chu, Carissa E.; Chou, Jonathan 分享 收藏
Bladder Cancer, Version 3.2024 Featured Updates to the NCCN Guidelines Flaig, Thomas W.; Spiess, Philippe E.; Abern, Michael; Agarwal, Neeraj; Bangs, Rick; Buyyounouski, Mark K.; Chan, Kevin; Chang, Sam S.; Chang, Paul; Friedlander, Terence; Greenberg, Richard E.; Guru, Khurshid A.; Herr, Harry W.; Hoffman-Censits, Jean; Kaimakliotis, Hristos; Kishan, Amar U.; Kundu, Shilajit; Lele, Subodh M.; Mamtani, Ronac; Mian, Omar Y.; Michalski, Jeff; Montgomery, Jeffrey S.; Parikh, Mamta; Patterson, Anthony; Peyton, Charles; Plimack, Elizabeth R.; Preston, Mark A.; Richards, Kyle; Sexton, Wade J.; Siefker-Radtke, Arlene O.; Stewart, Tyler; Sundi, Debasish; Tollefson, Matthew; Tward, Jonathan; Wright, Jonathan L.; Cassara, Carly J.; Gurski, Lisa A. 分享 收藏
Responders to combination radiation and PD-1 blockade demonstrate reduced myeloid immunosuppression and enhanced interferon signaling in oligometastatic prostate cancer patients Fan, Zenghua; Oh, David Y.; Wong, Anthony; Shinohara, Katsuto; Nguyen, Hao; Hwang, Caleb; Chang, Hewitt; Starzinski, Alec; Li, Tony; De Leon, Christopher; Gin, Marissa; Van Allen, Eliezer; Zhang, Li; Aggarwal, Rahaul R.; Friedlander, Terence W.; Small, Eric J.; Feng, Felix Y.; Fong, Lawrence 分享 收藏
Pemigatinib for metastatic or surgically unresectable urothelial carcinoma with FGF/FGFR genomic alterations: final results from FIGHT-201 Pemigatinib治疗转移性或手术不可切除的尿路上皮癌伴FGF/FGFR基因组改变: 来自FIGHT-201的最终结果 Necchi, A.; Pouessel, D.; Leibowitz, R.; Gupta, S.; Flechon, A.; Garcia-Donas, J.; Bilen, M. A.; Debruyne, P. R.; Milowsky, M. I.; Friedlander, T.; Maio, M.; Gilmartin, A.; Li, X.; Veronese, M. L.; Loriot, Y. 分享 收藏
Initial Experience with 68Ga-FAP-2286 PET Imaging in Patients with Urothelial Cancer 尿路上皮癌患者68Ga-FAP-2286 PET成像的初步经验 Koshkin, Vadim S.; Kumar, Vipul; Kline, Brad; Escobar, Domenique; Aslam, Maya; Cooperberg, Matthew R.; Aggarwal, Rahul R.; de Kouchkovsky, Ivan; Chou, Jonathan; Meng, Maxwell, V; Friedlander, Terence; Porten, Sima; Hope, Thomas A. 分享 收藏
A plain language summary exploring a new treatment combination for untreated locally advanced or metastatic urothelial cancer: enfortumab vedotin plus pembrolizumab 探索未经治疗的局部晚期或转移性尿路上皮癌的新治疗组合: enfortumab vedotin加pembrolizumab Hoimes, Christopher J.; Flaig, Thomas W.; Milowsky, Matthew, I; Friedlander, Terence W.; Bilen, Mehmet Asim; Gupta, Shilpa; Srinivas, Sandy; Merchan, Jaime R.; Mckay, Rana R.; Petrylak, Daniel P.; Sasse, Carolyn; Moreno, Blanca Homet; Yu, Yao; Carret, Anne-Sophie; Rosenberg, Jonathan E. 分享 收藏
A global, multicentre, open-label, randomised phase II trial of tobemstomig (tobe) with or without tiragolumab (tira) vs atezolizumab (atezo) in patients (pts) with untreated metastatic urothelial cancer (mUC) ineligible for platinumbased chemotherapy (chemo) Gupta, S.; Alhalabi, O.; Bamias, A.; Bellmunt, J.; Castellano Gauna, D. E.; Bedke, J.; Friedlander, T.; Garmezy, B.; Grivas, P.; Huddart, R. A.; Necchi, A.; Powles, T. B.; Puente, J.; Da Rosa, D. A. R.; Wang, F.; Lambertini, C.; Andreev-Drakhlin, A.; Fasso, M.; Loriot, Y. 分享 收藏
Atezolizumab plus Magrolimab, Niraparib, or Tocilizumab versus Atezolizumab Monotherapy in Platinum-Refractory Metastatic Urothelial Carcinoma: A Phase Ib/II Open-Label, Multicenter, Randomized Umbrella Study (MORPHEUS Urothelial Carcinoma) Drakaki, Alexandra; Powles, Thomas; Bamias, Aristotelis; Martin-Liberal, Juan; Shin, Sang Joon; Friedlander, Terence; Tosi, Diego; Park, Chandler; Gomez-Roca, Carlos; Lobbedez, Florence Joly; Castellano, Daniel; Morales-Barrera, Rafael; Moreno-Candilejo, Irene; Flechon, Aude; Yuen, Kobe; Rishipathak, Deepali; Dupree, Kelly; Young, Fiona; Michielin, Francesca; Shemesh, Colby S.; Steinberg, Elizabeth E.; Williams, Patrick; Lee, Jae Lyun 分享 收藏
Engaging Men of Diverse Racial and Ethnic Groups With Advanced Prostate Cancer in the Design of an mHealth Diet and Exercise Intervention: Focus Group Study Wang, Elizabeth Y.; Borno, Hala T.; Washington III, Samuel L.; Friedlander, Terence; Zhang, Sylvia; Trejo, Evelin; Van Blarigan, Erin L.; Chan, June M.; Shariff-Marco, Salma; Beatty, Alexis L.; Kenfield, Stacey A. 分享 收藏
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Somatic alterations of TP53 and MDM2 associated with response to enfortumab vedotin in patients with advanced urothelial cancer TP53和MDM2的体细胞改变与晚期尿路上皮癌患者对enfortumab vedotin的反应相关 Jindal, Tanya; Zhu, Xiaolin; Bose, Rohit; Kumar, Vipul; Maldonado, Edward; Deshmukh, Prianka; Shipp, Chase; Feng, Stephanie; Johnson, Michelle S.; Angelidakis, Austin; Kwon, Daniel; Borno, Hala T.; de Kouchkovsky, Ivan; Desai, Arpita; Aggarwal, Rahul; Fong, Lawrence; Small, Eric J.; Wong, Anthony; Porten, Sima; Chou, Jonathan; Friedlander, Terence; Koshkin, Vadim S. 分享 收藏
TROP2 Expression Across Molecular Subtypes of Urothelial Carcinoma and Enfortumab Vedotin-resistant Cells TROP2在尿路上皮癌和Enfortumab Vedotin耐药细胞分子亚型中的表达 Chou, Jonathan; Trepka, Kai; Sjostrom, Martin; Egusa, Emily A.; Chu, Carissa E.; Zhu, Jun; Chan, Emily; Gibb, Ewan A.; Badura, Michelle L.; Contreras-Sanz, Alberto; Stohr, Bradley A.; Meng, Maxwell, V; Pruthi, Raj S.; Lotan, Yair; Black, Peter C.; Porten, Sima P.; Koshkin, Vadim S.; Friedlander, Terence W.; Feng, Felix Y. 分享 收藏
CLINICAL AND PHARMACODYNAMIC BIOMARKER RESULTS FROM PORTER, A MULTI-COHORT PHASE 1 PLATFORM TRIAL OF COMBINATION IMMUNOTHERAPY FOR METASTATIC CASTRATION-RESISTANT PROSTATE CANCER PATIENTS Galsky, Matthew; Autio, Karen; Wentzel, Kristopher; Graff, Julie; Friedlander, Terence; Densmore, Julie; Cabanski, Christopher; Shotts, Kristin; Howes, Tim; Yu, Jia; Eisenbeisz, Elaine; Spasic, Marko; Maddock, Stephen; DaSilva, Diane; Kumar, Dinesh; Moore, Jonni; Schretzenmair, Richard; Lata, Jennifer; Xu, Arron; Reuschel, Emma; Wani, Snehal; Morrow, Matthew; Skolnik, Jeffrey; Santulli-Marotto, Sandra; Padron, Lacey; Butterfield, Lisa; LaVallee, Theresa; Bucktrout, Samantha; Yellin, Michael; Keler, Tibor; Salvador, Lisa; O'Donnell-Tormey, Jill; Lucey, Vanessa; Fairchild, Justin; Dugan, Ute; Bhardwaj, Nina; Subudhi, Sumit; Fong, Lawrence 分享 收藏
Prevalence of PD-L1 high expression in advanced urothelial carcinoma (aUC): Results from the PREVAIL prospective cohort study Grivas, P.; Agarwal, P. K.; Al-Ahmadie, H.; Friedlander, T.; Geynisman, D.; Hussain, I.; Lotan, Y.; Morgans, A. K.; Tesic-Schnell, M.; Meeks, J. 分享 收藏
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