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Michael Chisamore

merck & co., inc.
H指数:25
被引数:1,797

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Datopotamab Deruxtecan Plus Pembrolizumab With or Without Platinum-Based Chemotherapy for Advanced or Metastatic NSCLC: The Phase Ib TROPION-Lung02 Trial

Datopotamab Deruxtecan 联合帕博利珠单抗,联合或不联合铂类化疗治疗晚期或转移性非小细胞肺癌:TROPION-Lung02 Ib期试验

2026-03-210
PRE
Efficacy and Safety of Olomorasib in Combination with Pembrolizumab in Treatment of Patients with KRAS G12C-Mutant Advanced NSCLC

奥罗莫西布与帕博利珠单抗联合治疗KRAS G12C突变型晚期非小细胞肺癌的疗效与安全性

2025-11-290
PRE
First-Line Sacituzumab Govitecan Plus Pembrolizumab in Metastatic NSCLC: PD-L1 TPS <50% and ≥50% Cohorts of the EVOKE-02 Study

一线Sacituzumab Govitecan联合Pembrolizumab治疗转移性NSCLC:EVOKE-02研究PD-L1 TPS <50%和≥50%队列

2025-10-300
PRE
Phase 2 trial of imprime and pembrolizumab immunotherapy in metastatic triple negative breast cancer patients who have progressed beyond first line chemotherapy

二线化疗进展后的转移性三阴性乳腺癌患者中Imprime与Pembrolizumab免疫疗法的二期临床试验

2025-05-080
PRE
A PHASE 1, SAFETY LEAD-IN AND RANDOMIZED, OPEN-LABEL, PERIOPERATIVE STUDY OF VORASIDENIB COMBINED WITH PEMBROLIZUMAB IN RECURRENT OR PROGRESSIVE ENHANCING IDH-1 MUTANT GLIOMA: TRIAL IN PROGRESS
2024-11-110
PRE
Increased therapeutic index of muzastotug (ADG126), a masked anti-CTLA-4 antibody, in combination with pembrolizumab (pembro) enables significant clinical benefits and supports further clinical development in patients with metastatic MSS CRC

未修饰的抗-CTLA-4抗体muzastotug(ADG126)与pembrolizumab(pembro)联合应用,其治疗指数的增加可实现显著的临床获益,并支持其在转移性MSS结直肠癌患者中进一步的临床开发。

2024-09-010
PRE
A phase I/IIa first in-human phase I study of BI 1910, a monoclonal antibody agonistic to TNFR2, as a single agent and in combination with pembrolizumab in subjects with advanced solid tumors

一项关于BI 1910(一种针对TNFR2的单克隆抗体激动剂)的I/IIa期首次人体I期研究,作为单一药物以及与pembrolizumab联用,用于治疗晚期实体瘤患者。

2024-09-010
PRE
Case report of fatal immune-mediated myocarditis following treatment with davoceticept (ALPN-202), a PD-L1-dependent CD28 costimulator and dual PD-L1/CTLA-4 checkpoint inhibitor, in combination with pembrolizumab
2024-08-131
OAAI
Phase 2 study of oral CCR4 antagonist FLX475 (tivumecirnon) plus pembrolizumab in subjects with head and neck squamous cell carcinoma (HNSCC) previously treated with checkpoint inhibitor
2024-04-051
PRE
Trial in progress: A phase I, open-label, multicenter study of ZL-1218, an anti-CCR8 IgG1, as a single agent and as combination therapy with anti-PD-1 antibody to evaluate the safety, tolerability, and pharmacokinetics in subjects with advanced solid tumor
2024-04-050
PRE
Final top-line results of the BGBC008 phase II, multicenter study of bemcentinib and pembrolizumab (bem plus pembro) in second-line (2L) advanced non-squamous (NS) non-small cell lung cancer (NSCLC) (NCT03184571)
2023-10-010
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