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Phenotypic and clonal evolution of CD4 T cells in HNSCC during immunotherapy: a case report Paustian, Christopher; Moudgil, Tarsem Lal; Fesneau, Olivier; Simons, Noah; Rajamanickam, Venkatesh; Koguchi, Yoshinobu; Couey, Marcus; Bernard, Brady; Christie, Tanisha; Long, Annie; Rethwisch, Patrick; Hermann, Robert; Samson, Kimberly; Redmond, William L.; Bell, Bryan; Bifulco, Carlo; Hilton, Traci; Hu, Hong-Ming; Piening, Brian; Jensen, Shawn M.; Urba, Walter John; Duhen, Thomas; Leidner, Rom; Fox, Bernard 分享 收藏
Identification of a TCR to a non-canonical peptide (NCP) presented by the autologous non-small cell lung cancer (NSCLC) following an immunotherapy that includes canonical and NCPs 3338 Moudgil, Tarsem Lal; Hilton, Traci; Fesneau, Olivier; Shih, Yi-Ping; Paustian, Christopher; Simons, Noah; Koguchi, Yoshinobu; Rajamanickam, Venkatesh; Meng, Ryan; Bernard, Brady; Iwamoto, Noriko; Minegishi, Yuriko; Ueda, Koji; Fisher, Brenda; Tsu, Blake; Kairs, Stefanie; Barnes, Chris; Redmond, William L.; Shimada, Takashi; Bifulco, Carlo; Hu, Hong-Ming; Tran, Eric; Urba, Walter John; Duhen, Thomas; Leidner, Rom; Li, Rui; Sanborn, Rachel; Fox, Bernard 分享 收藏
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AFNT-211: A phase1 study of autologous CD4+and CD8+T cells engineered to express a high avidity HLA-A*11:01-restricted, KRAS G12V-specific, transgenic TCR; CD8α/β coreceptor; and a FAS41BB switch receptor in patients with advanced/metastatic solid tumors Mitchell, Shaunica; Khan, Binaish; Payumo, Francis; Chiorean, E. Gabriela; Gahvari, Zhubin; Hecht, J. Randolph; Hurwitz, Michael; Leidner, Rom; Lenz, Heinz-Josef; Pelster, Meredith; Punekar, Salman; Schoenfeld, Adam; Zhao, Dan; Vallaster, Markus; Nagorsen, Dirk 分享 收藏
Novel antibodies against a KK-LC-1-derived peptide presented on HLA-A*01 on tumor cells Scheifele, Fabian; Jungmichel, Stephanie; Alijaj, Nagjie; Dasargyri, Athanasia; Doerig, Romina; Knobel, Philip; Merten, Hannes; Richle, Philipp; Schleier, Thomas; Sobieraj, Anna; Vantellini, Alessio; Fugmann, Tim; Leidner, Rom; Biswas, Swethajit; Borras, Leonardo 分享 收藏
Trial in progress: A phase 1, first in human clinical trial for T-Plex, a multiplexed, enhanced T cell receptor-engineered T cell therapy (TCR-T) for solid tumors Moser, Justin; Pico, Brian; Henick, Brian; Leidner, Rom; Weiss, Jared; Isaacs, James; Grewal, Jaspreet; Hurwitz, Michael; Murray, Jim; Motta, Marlyane; Wang, Yun; Chattopadhyay, Shrikanta; Barton, Debora; MacBeath, Gavin; Thomas, Sajeve 分享 收藏
An off-the-shelf multivalent vaccine containing cancer's dark matter, DPV-001, combined with PD-1+/- GITR in head & neck cancer: safety, efficacy, and immunodynamics from the phase 1 GITRVax trial Leidner, Rom S.; Paustian, Christopher; Jensen, Shawn M.; Moudgil, Tarsem; Koguchi, Yoshinobu; Simons, Noah; Rajamanickam, Venkatesh; Meng, Ryan; Couey, Marcus A.; Vu, Quyen; Taylor, Matthew H.; Long, Anne; Staeck, Abigail J.; Kaur, Lakhvir; Jovanovic, Tijana; Bernard, Brady; Christie, Tanisha; Iwamoto, Noriko; Minegishi, Yuriko; Ueda, Koji; Redmond, William; Rushforth, Lessli M.; Shimada, Takashi; Rethwisch, Patrick; Patel, Ashish; Bell, Richard B.; Bifulco, Carlo B.; Hilton, Traci L.; Hu, Hong-Ming; Piening, Brian; Urba, Walter J.; Fox, Bernard A. 分享 收藏
First-in-human phase I/Ib study of NIZ985, a recombinant heterodimer of IL-15 and IL-15Rα, as a single agent and in combination with spartalizumab in patients with advanced and metastatic solid tumors Leidner, Rom; Conlon, Kevin; Mcneel, Douglas G.; Wang-Gillam, Andrea; Gupta, Sumati; Wesolowski, Robert; Chaudhari, Monica; Hassounah, Nadia; Lee, Jong Bong; Lee, Lang Ho; O'Keeffe, Jessica A.; Lewis, Nancy; Pavlakis, George N.; Thompson, John A. 分享 收藏
Precise tumor & patient selection for CDR404: A bispecific & bivalent MAGE-A4 T cell engager Giacomazzi, G.; Liivrand, M.; Hieta, R.; Dupuis, N.; Rondas, D.; Swatkowski, P.; Vrohlings, M.; Lenherr-Frey, D.; Borras, L.; Biswas, S.; Leidner, R.; Calvo, E. 分享 收藏
Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 1st-3rd, 2022-Naples, Italy) 黑色素瘤的观点: 黑色素瘤桥会议报告 (2022年12月1至3日-意大利那不勒斯) Ascierto, Paolo A.; Agarwala, Sanjiv S.; Warner, Allison Betof; Ernstoff, Marc S.; Fox, Bernard A.; Gajewski, Thomas F.; Galon, Jerome; Garbe, Claus; Gastman, Brian R.; Gershenwald, Jeffrey E.; Kalinski, Pawel; Krogsgaard, Michelle; Leidner, Rom S.; Lo, Roger S.; Menzies, Alexander M.; Michielin, Olivier; Poulikakos, Poulikos I.; Weber, Jeffrey S.; Caraco, Corrado; Osman, Iman; Puzanov, Igor; Thurin, Magdalena 分享 收藏
Crizotinib (C) in patients (pts) with solid tumors with MET amplification (amp) or mutation (mut): Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) Study Mileham, Kathryn F.; Rothe, Michael; Mangat, Pam K.; Garrett-Mayer, Elizabeth; Duvivier, Herbert L.; Calfa, Carmen J.; Dul, Carrie L.; Marr, Alissa S.; Ahn, Eugene R.; Behl, Deepti; Hall, Michael J.; Mehmi, Inderjit; Gaba, Anu; Leidner, Rom; Zalupski, Mark M.; Grantham, Gina N.; Gregory, Abigail; Halabi, Susan; Schilsky, Richard L. 分享 收藏
Trial in progress: First-in-human immunotherapy-trio for advanced head and neck squamous cell carcinoma Couey, Marcus A.; Taylor, Matthew; Moudgil, Tarsem; Koguchi, Yoshinobu; Stadum, Anne; Christie, Tanisha; Redmond, William L.; Paustian, Christopher; Meng, Ryan; Rajamanickam, Venkatesh; Rushforth, Lessli; Peterson, Abigail; Bernard, Brady; Bell, Richard B.; Bifulco, Carlo B.; Hilton, Traci L.; Jensen, Shawn M.; Hu, Hong-Ming; Piening, Brian; Urba, Walter J.; Fox, Bernard A.; Leidner, Rom S. 分享 收藏
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Multi-parametric comparison of scRNA-seq with CITE-seq and ultrahigh-plex spatial phenotyping of proteins in FFPE head and neck tumor biopsies: An opportunity to generate uniquely comprehensive multi-omic single cell datasets to investigate the tumor microenvironment Pratapa, Aditya; Jensen, Shawn M.; Jhaveri, Niyati; Koguchi, Yoshinobu; Rajamanickam, Venkatesh; Bernard, Brady; Christie, Tanisha; Piening, Brian; Leidner, Rom S.; Braubach, Oliver; Fox, Bernard A. 分享 收藏
Safety of Nivolumab Added to Chemoradiation Therapy Platforms for Intermediate and High-Risk Locoregionally Advanced Head and Neck Squamous Cell Carcinoma: RTOG Foundation 3504 Gillison, Maura L.; Ferris, Robert L.; Harris, Jonathan; Colevas, A. Dimitrios; Mell, Loren K.; Kong, Christina; Jordan, Richard C.; Moore, Kevin L.; Truong, Minh-Tam; Kirsch, Claudia; Chakravarti, Arnab; Blakaj, Dukagjin M.; Clump, David A.; Ohr, James P.; Deeken, John F.; Gensheimer, Michael F.; Saba, Nabil F.; Dorth, Jennifer A.; Rosenthal, David I.; Leidner, Rom S.; Kimple, Randall J.; Machtay, Mitchell; Curran, Walter J., Jr.; Torres-Saavedra, Pedro; Le, Quynh Thu 分享 收藏
Chemoradiation therapy alters the PD-L1 score in locoregional recurrent squamous cell carcinomas of the head and neck Park, Brian J.; Mattox, Austin K.; Clayburgh, Daniel; Patel, Mihir; Bell, R. Bryan; Yueh, Bevan; Leidner, Rom; Xiao, Hong; Couey, Marcus; Li, Shiting; Qin, Tingting; Sartor, Maureen A.; Cairns, Belinda; MacDonough, Tracy; Halliwill, Kyle; Deschler, Daniel; Lin, Derrick T.; Faquin, William C.; Sadow, Peter M.; Pai, Sara, I 分享 收藏
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Neoantigen T-Cell Receptor Gene Therapy in Pancreatic Cancer Leidner, Rom; Silva, Nelson Sanjuan; Huang, Huayu; Sprott, David; Zheng, Chunhong; Shih, Yi-Ping; Leung, Amy; Payne, Roxanne; Sutcliffe, Kim; Cramer, Julie; Rosenberg, Steven A.; Fox, Bernard A.; Urba, WalterJ; Tran, Eric 分享 收藏
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