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Periductal fibroblasts participate in liver homeostasis, fibrosis, and tumorigenesis 导管周围成纤维细胞参与肝脏稳态、纤维化和肿瘤发生。 Wang, Shan-Shan; Yuan, Jia; Tang, Xinyu Thomas; Yin, Xiujuan; Fang, Ke; Chen, Lin Veronica; Ren, Zhenggang; Zhou, Bo O. 分享 收藏
Safety and efficacy of PD-1 inhibitor (sintilimab) combined with transarterial chemoembolization as the initial treatment in patients with intermediate-stage hepatocellular carcinoma beyond up-to-seven criteria PD-1抑制剂（sintilimab）联合经动脉化疗栓塞作为超出“up-to-seven”标准的 intermediate-stage 肝细胞癌患者的初始治疗的安全性与有效性 Li, Lixing; Xu, Xin; Wang, Wentao; Huang, Peiran; Yu, Lei; Ren, Zhenggang; Fan, Jia; Zhou, Jian; Zhang, Lan; Wang, Zheng 分享 收藏
Impact of baseline tumour burden on outcomes in EMERALD-1: A phase III study of durvalumab (D) ± bevacizumab (B) with transarterial chemoembolisation (TACE) in embolisation-eligible unresectable hepatocellular carcinoma (uHCC) EMERALD-1研究中基线肿瘤负荷对结局的影响：一项关于度伐利尤单抗（D）±贝伐珠单抗（B）联合经动脉化疗栓塞（TACE）在栓塞适应症的不可切除肝细胞癌（uHCC）中的III期研究 Kudo, M.; Lencioni, R.; Erinjeri, J.; Chan, S. L.; Qin, S.; Ren, Z.; Arai, Y.; Heo, J.; Breder, V. V.; Bouattour, M.; Dayyani, F.; Yoon, J-H.; Chiu, C-F.; Suttichaimongkol, T.; Decaens, T.; Griffin, R.; Morgan, C.; Ali, S. K.; Balaji, K.; Sangro, B. 分享 收藏
KEYNOTE-966: 3-year follow-up for pembrolizumab (pembro) plus gemcitabine and cisplatin (gem/cis) vs placebo (pbo) plus gem/cis for patients (pts) with advanced biliary tract cancer (BTC) KEYNOTE-966： Pembrolizumab（pembro）联合吉西他滨和顺铂（gem/cis）对比安慰剂（pbo）联合吉西他滨和顺铂，用于晚期胆道癌（BTC）患者的3年随访研究。 Ueno, M.; Finn, R. S.; Yoo, C.; Ren, Z.; Furuse, J.; Kelley, R. K.; Chan, S. L.; Edeline, J.; Klumpen, H. J.; Yau, T.; Verslype, C.; Ozaka, M.; Bouattour, M.; Park, J. O.; Vogel, A.; Valle, J. W.; Starkopf, L.; Malhotra, U.; Siegel, A. B.; Qin, S. 分享 收藏
Efficacy and safety in the KEYNOTE-966 study of pembrolizumab (pembro) plus gemcitabine and cisplatin (gem/cis) for advanced biliary tract cancer (BTC): Impact of hepatitis B virus (HBV) infection KEYNOTE-966研究评估帕博利珠单抗（pembro）联合吉西他滨和顺铂（gem/cis）治疗晚期胆道癌（BTC）的疗效与安全性：乙型肝炎病毒（HBV）感染的影响 Yau, T.; Chan, S. L.; Kelley, R. K.; Finn, R. S.; Yoo, C.; Furuse, J.; Ren, Z.; Klumpen, H. J.; Ozaka, M.; Pelzer, U.; Arslan, C.; Park, J. O.; Edeline, J.; Valle, J. W.; Ueno, M.; Vogel, A.; Starkopf, L.; Malhotra, U.; Siegel, A. B.; Qin, S. 分享 收藏
Outcomes by baseline tumour burden in EMERALD-1: A phase III, randomised, placebo (PBO)-controlled study of durvalumab (D) ± bevacizumab (B) with transarterial chemoembolisation (TACE) in participants (pts) with embolisation-eligible unresectable hepatocellular carcinoma (uHCC) EMERALD-1研究中的基线肿瘤负荷分层结果：一项评估度伐利尤单抗（D）联合或不联合贝伐珠单抗（B）与经动脉化疗栓塞术（TACE）治疗栓塞术适用型不可切除性肝细胞癌（uHCC）患者的III期、随机、安慰剂（PBO）对照研究 Kudo, M.; Lencioni, R.; Erinjeri, J. P.; Chan, S. L.; Qin, S.; Ren, Z.; Arai, Y.; Heo, J.; Breder, V.; Bouattour, M.; Dayyani, F.; Yoon, J-H.; Chiu, C-F.; Suttichaimongkol, T.; Decaens, T.; Griffin, R.; Morgan, C.; Ali, S. K.; Balaji, K.; Sangro, B. 分享 收藏
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A single-arm open-label pilot study of combination therapy of TACE in combination with ablation and durvalumab in unresectable hepatocellular carcinoma patients (TAD study) 在不可切除的肝细胞癌患者中，TACE联合消融和durvalumab联合治疗的单臂开放标签试点研究 (TAD研究) Tang, B.; Yuan, J.; Lu, Z.; Yin, X.; Chen, R.; Tang, M.; Gan, Y.; Zhang, L.; Huang, L.; Ren, Z. 分享 收藏
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Proteomic and metabolomic features in patients with HCC responding to lenvatinib and anti-PD1 therapy Li, Zhong-Chen; Wang, Jie; Liu, He-Bin; Zheng, Yi-Min; Huang, Jian-Hang; Cai, Jia-Bin; Zhang, Lei; Liu, Xin; Du, Ling; Yang, Xue-Ting; Chai, Xiao-Qiang; Jiang, Ying-Hua; Ren, Zheng-Gang; Zhou, Jian; Fan, Jia; Yu, De-Cai; Sun, Hui-Chuan; Huang, Cheng; Liu, Feng 分享 收藏
A synergistic regulation works in matrix stiffness-driven invadopodia formation in HCC 协同调节在HCC中基质刚度驱动的invadopodia形成中起作用 Zhang, Xi; Zhao, Yingying; Li, Miao; Wang, Mimi; Qian, Jiali; Wang, Zhiming; Wang, Yaohui; Wang, Fan; Guo, Kun; Gao, Dongmei; Zhao, Yan; Chen, Rongxin; Ren, Zhenggang; Song, Haiyan; Cui, Jiefeng 分享 收藏
A Phase 3 Study of Pembrolizumab versus Placebo for Previously Treated Patients from Asia with Hepatocellular Carcinoma: Health-Related Quality of Life Analysis from KEYNOTE-394 Qin, Shukui; Fang, Weijia; Ren, Zhenggang; Ou, Shuangyan; Lim, Ho Yeong; Zhang, Feng; Lee, Kin Chung; Choi, Hye Jin; Tong, Jiandong; Tao, Min; Xu, Aibing; Cheng, Ashley; Lu, Chang-Hsien; Chiu, Chang-Fang; Wahid, Mohamed Ibrahim Abdul; Kamble, Shital; Norquist, Josephine M.; Zhong, Wenyan; Li, Chen; Chen, Zhendong 分享 收藏
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