John O’Leary - Publications, H-index & Citations

John O’Leary

Trinity College Dublin

59H指数

517论文数

1.4W被引数

收录论文 134

发表时间

Androgen drives early endosome vesicular trafficking machinery expression to alter Appl1 endosome and leptin signaling in prostate cancer 雄激素驱动早期内体囊泡转运机制的表达，以改变前列腺癌中Appl1内体和瘦素信号通路

Cell Communication and Signaling

IF8.9

2026-09-09

OAAI

Bukuru D. Nturubika; Courtney R. Moore; Jessica M. Logan; Clifford Young; Madison T. Hindes; Ruth Williams; Ian R. D. Johnson; Peter Hoffmann; Natansh D. Modi; Hugo Albrecht; John J. O’Leary; Philip A. Gregory; Douglas A. Brooks

Size-exclusion chromatography as a clinically applicable method for extracellular vesicles collection as liquid biopsies shows potential diagnostic relevance and correlation with poorer outcome in common cancer types 尺寸排阻色谱法作为临床适用的细胞外囊泡液体活检收集方法，显示出潜在的诊断相关性并与常见癌症类型的较差预后相关

Translational Oncology

IF4.1

2026-08-01

PREAI

Belenyesi, Szilard-Krisztian; Patmore, Sean; Hurley, Sinead; Oner, Ezgi; Saini, Volga M.; Kanjuga, Marika; Lewis, Faye; Menon, Meghana S.; Cahill, Christina; Tierney, Antonia; Deac, Oana; Martinez, Maria Jose Santos; Lowery, Maeve A.; O'Leary, John J.; Gately, Kathy; O'Toole, Sharon; O'Driscoll, Lorraine

Lipid metabolism in γδ T-cell activation: Implications for immunotherapy in ovarian cancer γδ T细胞活化中的脂质代谢：对卵巢癌免疫疗法的启示

Translational Oncology

IF4.1

2026-07-27

OAAI

Karolina Stirblyte; Yazid Ghanem; Mark Bates; Steven G. Gray; Feras Abu Saadeh; Cara Martin; Sharon O'Toole; John J. O'Leary; Derek G. Doherty; Bashir M. Mohamed

Crosstalk Between Inflammasome Signalling and Epithelial-Mesenchymal Transition in Cancer and Benign Disease: Mechanistic Insights, Context-Dependence, and Therapeutic Opportunities 炎症小体信号与上皮-间质转化在癌症和良性疾病中的串扰：机制洞察、情境依赖性和治疗机遇

Cells

IF5.2

2026-03-03

OAAI

Abdul L. Shakerdi; Emma Finnegan; Yin-Yin Sheng; Karlo Vidovic; Jessica M. Logan; Mark P. Ward; Sharon A. O’Toole; Cara Martin; Stavros Selemidis; Doug Brooks; John J. O’Leary; Prerna Tewari

TLR7-mediated inflammation drives PD-L1 upregulation and T cell exhaustion during influenza A virus infection TLR7介导的炎症驱动流感A病毒感染期间PD-L1上调和T细胞耗竭

iScience

IF4.1

2026-01-22

OAAI

Mark A. Miles; Stella Liong; Felicia Liong; John J. O’Leary; Doug A. Brooks; Stavros Selemidis

Pathogenesis-Guided Biomarker Assessment: A Shift in Prostate Cancer Diagnostics 基于发病机制的生物标志物评估：前列腺癌诊断领域的一次转变

International Journal of Molecular Sciences

IF4.9

2025-12-05

OAAI

Jessica M. Logan; Victoria Malone; John J. O’Leary; Doug A. Brooks

Implications of Altered Endosomal–Lysosomal Biogenesis in Melanoma Pathogenesis 溶酶体-溶酶体生物发生改变在黑色素瘤发病机制中的意义

International Journal of Molecular Sciences 2025, Vol. 26, Page 10113

IF0

2025-10-17

OAAI

Giang T. Lam; Carmela Martini; Alexandra Sorvina; Shane M. Hickey; Madison T. Hindes; David Waugh; John J. O’Leary; Douglas A. Brooks; Jessica M. Logan

Circulating tumour cells are a prognostic indicator in advanced high-grade serous ovarian cancer and are associated with platelets and immune cells following dissemination 循环肿瘤细胞是晚期高级别浆液性卵巢癌的预后指标，且在播散后与血小板和免疫细胞相关联。

British Journal of Cancer

IF6.8

2025-10-10

OAAI

Mark P. Ward; Faye Lewis; Catherine O’Gorman; Lucy A. Norris; Sarah E. Lochrin; Laura E. Kane; Tanya E. Kelly; Bashir M. Mohamed; Ashitha Ramesh; Roisin O’Connor; Elaine Kilgour; Brian Henderson; Marika Kanjuga; Sinead Hurley; Laura Edgerton; Prerna Tewari; Kathy Gately; Lorraine O’Driscoll; Karsten Hokamp; Siobhan Cashman; Gavin McManus; Doug A. Brooks; Stavros Selemidis; Niamh Coleman; John Kennedy; Waseem Kamran; James P. Beirne; Patrick Maguire; Feras Abu Saadeh; Karen Cadoo; Cara M. Martin; John J. O’Leary; Sharon A. O’Toole

Reply to: In reference to “A pilot study evaluating the feasibility of enriching and detecting circulating tumour cells from peripheral and ovarian veins in rare epithelial ovarian carcinomas”回复：关于“一项评估从外周静脉和卵巢静脉中富集和检测罕见上皮性卵巢癌细胞的可行性研究”

european journal of oncology

IF0

2025-06-02

PREAI

Faye Lewis; Mark P. Ward; Feras Abu Saadeh; John J. O'Leary; Sharon A. O'Toole

Exploring the Contribution of TLR7 to Sex-Based Disparities in Respiratory Syncytial Virus (RSV)-Induced Inflammation and Immunity

VIRUSES-BASEL

IF3.5

2025-03-16

OAAI

Miles, Mark A.; Huttmann, Thomas D.; Liong, Stella; Liong, Felicia; O'Leary, John J.; Brooks, Doug A.; Selemidis, Stavros

Genetics And Survival Outcomes In Young-Onset Ovarian Cancer: Insights From An 18-Year Tertiary Referral Center Study 遗传因素与年轻发病卵巢癌的生存结局：一项为期18年的三级转诊中心研究的启示

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

IF4.7

2025-02-01

PREAI

Mcnevin, Ciara; Dillion, Rachel; Hollingsworth, Simon; Lewis, Faye; Hurley, Sinead; Norris, Lucy A.; Ward, Mark; Donachie, Vicky; Maguire, Patrick J.; Alken, Scheryll; Coleman, Niamh; Kamran, Waseem; Abu Saadeh, Feras; O'Gorman, Catherine; Donnell, Dearbhaile O.; D'Arcy, Tom; O'Leary, John; Finn, Stephen; O'Toole, Sharon A.; Cadoo, Karen

Metabolic reprogramming, malignant transformation and metastasis: Lessons from chronic lymphocytic leukaemia and prostate cancer 代谢重编程、恶性转化和转移：从慢性淋巴细胞白血病和前列腺癌中得到的启示

CANCER LETTERS

IF10.1

2025-02-01

PREAI

Hindes, Madison T.; Mcelligott, Anthony M.; Best, Oliver G.; Ward, Mark P.; Selemidis, Stavros; Miles, Mark A.; Nturubika, Bukuru D.; Gregory, Philip A.; Anderson, Paul H.; Logan, Jessica M.; Butler, Lisa M.; Waugh, David J.; O'Leary, John J.; Hickey, Shane M.; Thurgood, Lauren A.; Brooks, Douglas A.

Chemotherapy alters thrombomodulin and factor VIIIc expression resulting in acquired activated protein C resistance and enhanced thrombin generation in cancer associated thrombosis

THROMBOSIS RESEARCH

IF3.4

2025-02-01

OAAI

Ward, M. P.; Ibrahim, E. M.; O'Toole, S. A.; Marchocki, Z.; O'Leary, J. J.; Abu Saadeh, F.; Norris, L. A.

Unravelling the biological and clinical challenges of circulating tumour cells in epithelial ovarian carcinoma

CANCER LETTERS

IF10.1

2024-11-01

OAAI

Lewis, Faye; Beirne, James; Henderson, Brian; Norris, Lucy; Cadoo, Karen; Kelly, Tanya; Martin, Cara; Hurley, Sinead; Kanjuga, Marika; O'Driscoll, Lorraine; Gately, Kathy; Oner, Ezgi; Saini, Volga M.; Brooks, Doug; Selemidis, Stavros; Kamran, Waseem; Haughey, Niamh; Maguire, Patrick; O'Gorman, Catherine; Abu Saadeh, Feras; Ward, Mark P.; O'Leary, John J.; O'Toole, Sharon A.

Biomarkers in high grade serous ovarian cancer 高级别浆液性卵巢癌的生物标志物

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

IF8.3

2024-11-01

PREAI

Bates, Mark; Mohamed, Bashir M.; Lewis, Faye; O'Toole, Sharon; O'Leary, John J.

Altered expression of vesicular trafficking machinery in prostate cancer affects lysosomal dynamics and provides insight into the underlying biology and disease progression

BRITISH JOURNAL OF CANCER

IF6.8

2024-08-31

OAAI

Nturubika, Bukuru D.; Guardia, Carlos M.; Gershlick, David C.; Logan, Jessica M.; Martini, Carmela; Heatlie, Jessica K.; Lazniewska, Joanna; Moore, Courtney; Lam, Giang T.; Li, Ka L.; Ung, Ben S-Y; Brooks, Robert D.; Hickey, Shane M.; Bert, Andrew G.; Gregory, Philip A.; Butler, Lisa M.; O'Leary, John J.; Brooks, Douglas A.; Johnson, Ian R. D.

Potential role of the CD39-CD73 ATP-adenosine pathway in platelet mediated dissemination of circulating tumour cells

BRITISH JOURNAL OF CANCER

IF6.8

2024-08-11

PREAI

Ward, Mark P.; O'Toole, Sharon A.; O'Leary, John J.

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

MOLECULAR ONCOLOGY

IF4.5

2024-08-06

OAAI

Saini, Volga; Oner, Ezgi; Ward, Mark P.; Hurley, Sinead; Henderson, Brian David; Lewis, Faye; Finn, Stephen P.; Fitzmaurice, Gerard J.; O'Leary, John J.; O'Toole, Sharon; O'Driscoll, Lorraine; Gately, Kathy

Low dose aspirin prevents endothelial dysfunction in the aorta and foetal loss in pregnant mice infected with influenza A virus

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-04-04

OAAI

Coward-Smith, Madison; Liong, Stella; Oseghale, Osezua; Erlich, Jonathan R.; Miles, Mark A.; Liong, Felicia; Brassington, Kurt; Bozinovski, Steven; Vlahos, Ross; Brooks, Robert D.; Brooks, Doug A.; O'Leary, John J.; Selemidis, Stavros

Exploring the role of sporadic BRAF and KRAS mutations during colorectal cancer pathogenesis: A spotlight on the contribution of the endosome-lysosome system

CANCER LETTERS

IF10.1

2024-03-01

OAAI

Tang, Jingying; Lam, Giang T.; Brooks, Robert D.; Miles, Mark; Useckaite, Zivile; Johnson, Ian R. D.; Ung, Ben S. -Y.; Martini, Carmela; Karageorgos, Litsa; Hickey, Shane M.; Selemidis, Stavros; Hopkins, Ashley M.; Rowland, Andrew; Vather, Ryash; O'Leary, John J.; Brooks, Douglas A.; Caruso, Maria C.; Logan, Jessica M.

研究方向