Lee J. Martin - Publications, H-index & Citations

Lee J. Martin

johns hopkins university

86H指数

333论文数

2.7W被引数

收录论文 90

发表时间

Calretinin and Parvalbumin Trapping of TDP43 and XRCC1 Instructs Neocortical Interneuron Death in Neonatal Hypoxic-Ischemic Encephalopathy 钙视网膜蛋白和帕尔瓦布明捕获TDP43和XRCC1指导新生儿缺氧缺血性脑病中大脑新皮层 interneuron 的死亡

Biomolecules

IF4.8

2026-04-22

OAAI

Lee J. Martin; Rebecca N. Ichord; Caitlin E. O’Brien; Sophie Yohannan; Danay Fernandez; Annalise Garrido; Naya Amauri; Dongseok Park; Jordan Benderoth; Jennifer K. Lee

Human Mutant Dynactin Subunit 1 Causes Profound Motor Neuron Disease Consistent with Possible Mechanisms Involving Axonopathy, Mitochondriopathy, Protein Nitration, and T-Cell-Mediated Cytolysis 人类突变动力素亚基1导致严重运动神经元疾病，其机制可能与轴突病变、线粒体病变、蛋白质亚硝基化及T细胞介导的细胞溶解有关。

Biomolecules 2025, Vol. 15, Page 1637

IF4.8

2025-11-21

OAAI

Victor Xie; Maria Clara Franco; Lee J. Martin

Human Apolipoprotein E ε4 Allele Modulates Energy Substrate Availability, Seizure Burden, Mortality and Hippocampal Injury, Cell Death, and Inflammation after Neonatal Hypoxic-Ischemic Brain Injury 人类载脂蛋白E ε4等位基因调节新生儿缺氧缺血性脑损伤后的能量底物可用性、癫痫负担、死亡率以及海马体损伤、细胞死亡和炎症。

DEVELOPMENTAL NEUROSCIENCE

IF2

2025-09-01

OAAI

Nazareth, Michelle; Duck, Sarah Ann; Fassinger, Abigail; Elmore, Genesis; Pinto, Charles; Nugent, Michael; St. Pierre, Mark; Lechner, Charles; Jantzie, Lauren L.; Northington, Frances J.; Vannucci, Susan J.; Martin, Lee J.; Chavez-Valdez, Raul

Hypothermia Shifts Neurodegeneration Phenotype in Neonatal Human Hypoxic-Ischemic Encephalopathy but Not in Related Piglet Models: Possible Relationship to Toxic Conformer and Intrinsically Disordered Prion-like Protein Accumulation 低温在新生儿缺氧缺血性脑病中改变了神经退行性表型，但在相关的猪模型中并未发生：可能与毒性构象和内在无序朊病毒样蛋白积累有关

CELLS

IF5.2

2025-04-12

OAAI

Martin, Lee J.; Lee, Jennifer K.; Niedzwiecki, Mark V.; Almira, Adriana Amrein; Javdan, Cameron; Chen, May W.; Olberding, Valerie; Brown, Stephen M.; Park, Dongseok; Yohannan, Sophie; Putcha, Hasitha; Zheng, Becky; Garrido, Annalise; Benderoth, Jordan; Kisner, Chloe; Ghaemmaghami, Javid; Northington, Frances J.; Kratimenos, Panagiotis

Human-robot interactions and experiences of staff and service robots in aged care

SCIENTIFIC REPORTS

IF3.9

2025-01-20

OAAI

Macalupu, Valeria; Miller, Evonne; Martin, Lee; Caldwell, Glenda

Neocortical cholinergic pathology after neonatal brain injury is increased by Alzheimer's disease-related genes in mice

NEUROBIOLOGY OF DISEASE

IF5.6

2024-10-01

OAAI

Doucette, Leslie; Turnbill, Victoria; Carlin, Katherine; Cavanagh, Andrew; Sollinger, Benjamin; Kuter, Nazli; Flock, Debra L.; Robinson, Shenandoah; Chavez-Valdez, Raul; Jantzie, Lauren; Martin, Lee J.; Northington, Frances J.

In vivo mapping of cellular resolution neuropathology in brain ischemia with diffusion MRI

SCIENCE ADVANCES

IF12.5

2024-07-19

OAAI

Wu, Dan; Lee, Hong-Hsi; Ba, Ruicheng; Turnbill, Victoria; Wang, Xiaoli; Luo, Yu; Walczak, Piotr; Fieremans, Els; Novikov, Dmitry S.; Martin, Lee J.; Northington, Frances J.; Zhang, Jiangyang

Proteasome localization and activity in pig brain and in vivo small molecule screening for activators

FRONTIERS IN CELLULAR NEUROSCIENCE

IF4

2024-02-26

OAAI

Almira, Adriana Amrein; Chen, May W.; El Demerdash, Nagat; Javdan, Cameron; Park, Dongseok; Lee, Jennifer K.; Martin, Lee J.

Hypothermic Protection in Neocortex Is Topographic and Laminar, Seizure Unmitigating, and Partially Rescues Neurons Depleted of RNA Splicing Protein Rbfox3/NeuN in Neonatal Hypoxic-Ischemic Male Piglets

CELLS

IF5.2

2023-10-15

OAAI

Primiani, Christopher T.; Lee, Jennifer K.; O'Brien, Caitlin E.; Chen, May W.; Perin, Jamie; Kulikowicz, Ewa; Santos, Polan; Adams, Shawn; Lester, Bailey; Rivera-Diaz, Natalia; Olberding, Valerie; Niedzwiecki, Mark V.; Ritzl, Eva K.; Habela, Christa W.; Liu, Xiuyun; Yang, Zeng-Jin; Koehler, Raymond C.; Martin, Lee J.

Aberrant DNA and RNA Methylation Occur in Spinal Cord and Skeletal Muscle of Human SOD1 Mouse Models of ALS and in Human ALS: Targeting DNA Methylation Is Therapeutic

CELLS

IF5.2

2022-10-31

OAAI

Martin, Lee J.; Adams, Danya A.; Niedzwiecki, Mark, V; Wong, Margaret

Oleuropein Activates Neonatal Neocortical Proteasomes, but Proteasome Gene Targeting by AAV9 Is Variable in a Clinically Relevant Piglet Model of Brain Hypoxia-Ischemia and Hypothermia

CELLS

IF5.2

2021-08-18

OAAI

El Demerdash, Nagat; Chen, May W.; O'Brien, Caitlin E.; Adams, Shawn; Kulikowicz, Ewa; Martin, Lee J.; Lee, Jennifer K.

Multi-Parametric Evaluation of Cerebral Hemodynamics in Neonatal Piglets Using Non-Contrast-Enhanced Magnetic Resonance Imaging Methods

JOURNAL OF MAGNETIC RESONANCE IMAGING

IF3.5

2021-05-06

OAAI

Liu, Dapeng; Jiang, Dengrong; Tekes, Aylin; Kulikowicz, Ewa; Martin, Lee J.; Lee, Jennifer K.; Liu, Peiying; Qin, Qin

Chronic Intermittent Mild Whole-Body Hypothermia Is Therapeutic in a Mouse Model of ALS

CELLS

IF5.2

2021-02-04

OAAI

Martin, Lee J.; Niedzwiecki, Mark V.; Wong, Margaret

Human Motor Neurons With SOD1-G93A Mutation Generated From CRISPR/Cas9 Gene-Edited iPSCs Develop Pathological Features of Amyotrophic Lateral Sclerosis

FRONTIERS IN CELLULAR NEUROSCIENCE

IF4

2020-11-19

OAAI

Kim, Byung Woo; Ryu, Jiwon; Jeong, Ye Eun; Kim, Juhyun; Martin, Lee J.

Combining Hypothermia and Oleuropein Subacutely Protects Subcortical White Matter in a Swine Model of Neonatal Hypoxic-Ischemic Encephalopathy

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

IF3

2020-11-19

OAAI

Lee, Jennifer K.; Santos, Polan T.; Chen, May W.; O'Brien, Caitlin E.; Kulikowicz, Ewa; Adams, Shawn; Hardart, Henry; Koehler, Raymond C.; Martin, Lee J.

Accumulation of PSA-NCAM marks nascent neurodegeneration in the dorsal hippocampus after neonatal hypoxic-ischemic brain injury in mice

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

IF4.5

2020-07-23

OAAI

Chavez-Valdez, Raul; Lechner, Charles; Emerson, Paul; Northington, Frances J.; Martin, Lee J.

Mean Diffusivity in Striatum Correlates With Acute Neuronal Death but Not Lesser Neuronal Injury in a Pilot Study of Neonatal Piglets With Encephalopathy

JOURNAL OF MAGNETIC RESONANCE IMAGING

IF3.5

2020-05-12

OAAI

Lee, Jennifer K.; Liu, Dapeng; Raven, Erika P.; Jiang, Dengrong; Liu, Peiying; Qin, Qin; Kulikowicz, Ewa; Santos, Polan T.; Adams, Shawn; Zhang, Jiangyang; Koehler, Raymond C.; Martin, Lee J.; Tekes, Aylin

DNA damage accumulates and responses are engaged in human ALS brain and spinal motor neurons and DNA repair is activatable in iPSC-derived motor neurons with SOD1 mutations

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2020-01-31

OAAI

Kim, Byung Woo; Jeong, Ye Eun; Wong, Margaret; Martin, Lee J.

Amyloid β toxic conformer has dynamic localization in the human inferior parietal cortex in absence of amyloid plaques

SCIENTIFIC REPORTS

IF3.9

2018-11-15

OAAI

Kageyama, Yusuke; Saito, Atsushi; Pletnikova, Olga; Rudow, Gay L.; Irie, Yumi; An, Yang; Murakami, Kazuma; Irie, Kazuhiro; Resnick, Susan M.; Fowler, David R.; Martin, Lee J.; Troncoso, Juan C.

Proteasome Biology Is Compromised in White Matter After Asphyxic Cardiac Arrest in Neonatal Piglets

JOURNAL OF THE AMERICAN HEART ASSOCIATION

IF5.3

2018-10-16

OAAI

Santos, Polan T.; O'Brien, Caitlin E.; Chen, May W.; Hopkins, C. Danielle; Adams, Shawn; Kulikowicz, Ewa; Singh, Rashmi; Koehler, Raymond C.; Martin, Lee J.; Lee, Jennifer K.

研究方向