John H. Wolfe - Publications, H-index & Citations

John H. Wolfe

research institute of children’s hospital of philadelphia

60H指数

304论文数

1.3W被引数

收录论文 73

发表时间

Effect of Disease Progression on CSF-Directed AAV Gene Therapy in a Large Brain Animal Model of Lysosomal Storage Disease 疾病进展对溶酶体贮积症大型脑动物模型中CSF导向的AAV基因治疗的影响

Molecular Therapy Methods & Clinical Development

IF4.7

2025-08-11

OAAI

Jacqueline E. Hunter; Caitlyn M. Molony; Wojciech K. Panek; Charles H. Vite; Sanjeev Chawla; Harish Poptani; John H. Wolfe

Choroid plexus-targeted viral gene therapy for alpha-mannosidosis, a prototypical neurometabolic lysosomal storage disease

HUMAN MOLECULAR GENETICS

IF3.2

2025-01-16

OAAI

Choi, Eun-Young; Wolfe, John H.; Kaler, Stephen G.

Systemic immunosuppression promotes survival and integration of subretinally implanted human ESC-derived photoreceptor precursors in dogs 系统性免疫抑制促进犬视网膜下植入的人ESC来源的感光细胞前体的存活和整合

STEM CELL REPORTS

IF5.1

2022-08-01

OAAI

Ripolles-Garcia, Ana; Dolgova, Natalia; Phillips, M. Joseph; Savina, Svetlana; Ludwig, Allison L.; Stuedemann, Sara A.; Nlebedum, Uchenna; Wolfe, John H.; Garden, Oliver A.; Maminishkis, Arvydas; Amaral, Juan; Bharti, Kapil; Gamm, David M.; Aguirre, Gustavo D.; Beltran, William A.

Global CNS correction in a large brain model of human alpha-mannosidosis by intravascular gene therapy

BRAIN

IF11.7

2020-07-16

OAAI

Yoon, Sea Young; Hunter, Jacqueline E.; Chawla, Sanjeev; Clarke, Dana L.; Molony, Caitlyn; O'Donnell, Patricia A.; Bagel, Jessica H.; Kumar, Manoj; Poptani, Harish; Vite, Charles H.; Wolfe, John H.

Integrated analysis of proteome and transcriptome changes in the mucopolysaccharidosis type VII mouse hippocampus

MOLECULAR GENETICS AND METABOLISM

IF3.5

2016-05-01

OAAI

Parente, Michael K.; Rozen, Ramona; Seeholzer, Steven H.; Wolfe, John H.

Clinical Improvement of Alpha-mannosidosis Cat Following a Single Cisterna Magna Infusion of AAV1

MOLECULAR THERAPY

IF12

2016-01-01

OAAI

Yoon, Sea Young; Bagel, Jessica H.; O'Donnell, Patricia A.; Vite, Charles H.; Wolfe, John H.

Diffusion Tensor Imaging for Assessing Brain Gray and White Matter Abnormalities in a Feline Model of α-Mannosidosis 扩散张量成像评估猫 α-甘露糖苷病模型的脑灰质和白质异常

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

IF3

2015-12-15

OAAI

Kumar, Manoj; Duda, Jeff T.; Yoon, Sea Young; Bagel, Jessica; O'Donnell, Patricia; Vite, Charles; Pickup, Stephen; Gee, James C.; Wolfe, John H.; Poptani, Harish

Ex Vivo Gene Therapy for Lysosomal Storage Disease in the CNS: Patient iPSC-Derived Neural Stem Cells Correct Pathology in the MPS VII Mouse Brain

MOLECULAR THERAPY

IF12

2015-05-01

OAAI

Griffin, Tagan A.; Anderson, Hayley C.; Wolfe, John H.

Ex Vivo Gene Therapy Using Patient iPSC-Derived NSCs Reverses Pathology in the Brain of a Homologous Mouse Model

STEM CELL REPORTS

IF5.1

2015-05-01

OAAI

Griffin, Tagan A.; Anderson, Hayley C.; Wolfe, John H.

Long-distance Axonal Transport of AAV9 Is Driven by Dynein and Kinesin-2 and Is Trafficked in a Highly Motile Rab7-positive Compartment

MOLECULAR THERAPY

IF12

2014-03-01

105

OAAI

Castle, Michael J.; Perlson, Eran; Holzbaur, Erika L. F.; Wolfe, John H.

High-Resolution Magnetic Resonance Microscopy and Diffusion Tensor Imaging to Assess Brain Structural Abnormalities in the Murine Mucopolysaccharidosis VII Model

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

IF3

2014-01-01

OAAI

Kumar, Manoj; Nasrallah, Ilya M.; Kim, Sungheon; Ittyerah, Ranjit; Pickup, Stephen; Li, Joel; Parente, Michael K.; Wolfe, John H.; Poptani, Harish

Engraftment of nonintegrating neural stem cells differentially perturbs cortical activity in a dose-dependent manner

MOLECULAR THERAPY

IF12

2013-12-01

OAAI

Weerakkody, Tanya N.; Patel, Tapan P.; Yue, Cuiyong; Takano, Hajime; Anderson, Hayley C.; Meaney, David F.; Coulter, Douglas A.; Wolfe, John H.

Transplantation of CD15-Enriched Murine Neural Stem Cells Increases Total Engraftment and Shifts Differentiation Toward the Oligodendrocyte Lineage

STEM CELLS TRANSLATIONAL MEDICINE

IF4.9

2013-05-16

OAAI

Chaubey, Sushma; Wolfe, John H.

Progress in gene therapy for neurological disorders

NATURE REVIEWS NEUROLOGY

IF33.1

2013-04-23

199

OAAI

Simonato, Michele; Bennett, Jean; Boulis, Nicholas M.; Castro, Maria G.; Fink, David J.; Goins, William F.; Gray, Steven J.; Lowenstein, Pedro R.; Vandenberghe, Luk H.; Wilson, Thomas J.; Wolfe, John H.; Glorioso, Joseph C.

Translating the Genomics Revolution: The Need for an International Gene Therapy Consortium for Monogenic Diseases

MOLECULAR THERAPY

IF12

2013-02-01

OAAI

Tremblay, Jacques P.; Xiao, Xiao; Aartsma-Rus, Annemieke; Barbas, Carlos; Blaus, Helen M.; Bogdanove, Adam J.; Boycott, Kym; Brauns, Serge; Breakefield, Xandra O.; Bueren, Juan A.; Buschmann, Michael; Byrne, Barry J.; Calos, Michele; Cathomen, Toni; Chamberlain, Jeffrey; Chuah, Marinee; Cornetta, Kenneth; Davies, Kay E.; Dickson, J. George; Duchateau, Philippe; Flotte, Terence R.; Gaudet, Daniel; Gersbach, Charles A.; Gilbert, Renald; Glorioso, Joseph; Herzog, Roland W.; High, Katherine A.; Huang, Wenlin; Huard, Johnny; Joung, J. Keith; Liu, Depei; Liu, Dexi; Lochmueller, Hanns; Lustig, Lawrence; Martens, Jeffrey; Massie, Bernard; Mavilio, Fulvio; Mendell, Jerry R.; Nathwani, Amit; Ponder, Katherine; Porteus, Matthew; Puymirat, Jack; Samulski, Jude; Takeda, Shin'ichi; Thrasher, Adrian; VandenDriessche, Thierry; Wei, Yuquan; Wilson, James M.; Wilton, Steve D.; Wolfe, John H.; Gao, Guangping

Expanding the use of simulation in open vascular surgical training

JOURNAL OF VASCULAR SURGERY

IF3.6

2012-09-01

OAAI

Pandey, Vikas A.; Wolfe, John H. N.

The changing management of primary mycotic aortic aneurysms

JOURNAL OF VASCULAR SURGERY

IF3.6

2011-08-01

OAAI

Vallejo, Nadia; Picardo, Natasha Emma; Bourke, Patricia; Bicknell, Colin; Cheshire, Nicholas J. W.; Jenkins, Michael P.; Wolfe, John; Gibbs, Richard G. J.

Dosage Thresholds for AAV2 and AAV8 Photoreceptor Gene Therapy in Monkey

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2011-06-22

195

OAAI

Vandenberghe, Luk H.; Bell, Peter; Maguire, Albert M.; Cearley, Cassia N.; Xiao, Ru; Calcedo, Roberto; Wang, Lili; Castle, Michael J.; Maguire, Alexandra C.; Grant, Rebecca; Wolfe, John H.; Wilson, James M.; Bennett, Jean

Hybrid Repair of the Aortic Arch in Patients with Extensive Aortic Disease

EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY

IF6.8

2010-12-01

OAAI

Antoniou, G. A.; Mireskandari, M.; Bicknell, C. D.; Cheshire, N. J. W.; Gibbs, R. G.; Hamady, M.; Wolfe, J. H. N.; Jenkins, M. P.

Hybrid Treatment of Complex Aortic Arch Disease with Supra-aortic Debranching and Endovascular Stent Graft Repair

EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY

IF6.8

2010-06-01

150

OAAI

Antoniou, G. A.; El Sakka, K.; Hamady, M.; Wolfe, J. H. N.

研究方向