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Identification of immunogenic HLA-A*02:01 epitopes associated with HCC for immunotherapy development Maino, Anthony; Bourova-Flin, Ekaterina; Decaens, Thomas; Khochbin, Saadi; Jilkova, Zuzana Macek; Rousseaux, Sophie; Plumas, Joel; Saas, Philippe; Chaperot, Laurence; Manches, Olivier 分享 收藏
Preliminary clinical results of a therapeutic cancer vaccine PDC*lung01 in combination with anti-PD-1 in patients (pts) with stage IV NSCLC Theelen, Willemijn; Perol, Maurice; Cuppens, Kristof; Demedts, Ingel; Borm, Frank; Biesma, Bonne; Wauters, Els; Colinet, Benoit; Buchmeier, Eva-Lotte; Althoff, Friederike; Pons-Tostivint, Elvire; Van de Kerkhove, Charlotte; Moro-Sibilot, Denis; Sibille, Anne; Derijcke, Sofie; Skrzypski, Marcin; Plumas, Joel; De Vos, Beatrice; Debruyne, Channa; Cantero, Frederique; Adriaenssens, Stefanie; Renard, Florence; Vansteenkiste, Johan 分享 收藏
PDC*lung01: An innovative therapeutic cancer vaccine induces specific immune responses in combination with anti- PD-1 treatment in patients with non-small cell lung cancer Plumas, Joel; Sibille, Anne; Demedts, Ingel; Pons-Tostivint, Elvire; Van de Kerkhove, Charlotte; Derijcke, Sofie; Theelen, Willemijn; Biesma, Bonne; Borm, Frank; Wauters, Els; Collodoro, Mike; Al Badawy, Kays; Duchayne, Camille; Debruyne, Channa; Devos, Beatrice; Colinet, Benoit; Moro-Sibilot, Denis; Perol, Maurice; Buchmeier, Eva-Lotte; Skrzypski, Marcin; Cuppens, Kristof; Vansteenkiste, Johan 分享 收藏
Open-label, dose escalation, phase I/II study to assess safety, tolerability, immunogenicity and preliminary clinical activity of the therapeutic cancer vaccine PDC*lung01 with or without anti-programmed death-1 (PD-1) treatment in patients with non-small cell lung cancer (NSCLC) Vansteenkiste, J. F.; Demedts, I.; Pons-Tostivint, E.; Biesma, B.; Borm, F.; Colinet, B.; Cuppens, K.; Derijcke, S.; Greillier, L.; Juergens, J.; Moro-Sibilot, D.; Perol, M.; Sebastian, M.; Skrzypski, M.; Theelen, W.; Van De Kerkhove, C.; Collodoro, M.; Plumas, J.; Debruyne, C.; Sibille, A. 分享 收藏
Engineering a Human Plasmacytoid Dendritic Cell-Based Vaccine to Prime and Expand Multispecific Viral and Tumor Antigen-Specific T-Cells 设计一种基于人浆细胞样树突状细胞的疫苗，以引发和扩增多特异性病毒和肿瘤抗原特异性T细胞 Lenogue, Kevin; Walencik, Alexandre; Laulagnier, Karine; Molens, Jean-Paul; Benlalam, Houssem; Dreno, Brigitte; Coulie, Pierre; Pule, Martin; Chaperot, Laurence; Plumas, Joel 分享 收藏
An innovative plasmacytoid dendritic cell line-based cancer vaccine primes and expands antitumor T-cells in melanoma patients in a first-in-human trial Charles, Julie; Chaperot, Laurence; Hannani, Dalil; Costa, Juliana; Templier, Isabelle; Trabelsi, Sabiha; Gil, Hugo; Moisan, Anaick; Persoons, Virginie; Hegelhofer, Harald; Schir, Edith; Quesada, Jean-Louis; Mendoza, Christophe; Aspord, Caroline; Manches, Olivier; Coulie, Pierre G.; Khammari, Amir; Dreno, Brigitte; Leccia, Marie-Therese; Plumas, Joel 分享 收藏
T-cell receptor diversity as a prognostic biomarker in melanoma patients T细胞受体多样性作为黑色素瘤患者的预后生物标志物 Charles, Julie; Mouret, Stephane; Challende, Isabelle; Leccia, Marie-Therese; De Fraipont, Florence; Perez, Solene; Plantier, Nadia; Plumas, Joel; Manuel, Manuarii; Chaperot, Laurence; Aspord, Caroline 分享 收藏
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The features of circulating and tumor-infiltrating γδ T cells in melanoma patients display critical perturbations with prognostic impact on clinical outcome 黑色素瘤患者中循环和肿瘤浸润性 γ δ T细胞的特征显示出严重的扰动，对临床结果具有预后影响 Girard, Pauline; Charles, Julie; Cluzel, Camille; Degeorges, Emmanuelle; Manches, Olivier; Plumas, Joel; De Fraipont, Florence; Leccia, Marie-Therese; Mouret, Stephane; Chaperot, Laurence; Aspord, Caroline 分享 收藏
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The MEK1/2-ERK Pathway Inhibits Type I IFN Production in Plasmacytoid Dendritic Cells Janovec, Vaclav; Aouar, Besma; Font-Haro, Albert; Hofman, Tomas; Trejbalova, Katerina; Weber, Jan; Chaperot, Laurence; Plumas, Joel; Olive, Daniel; Dubreuil, Patrice; Nunes, Jacques A.; Stranska, Ruzena; Hirsch, Ivan 分享 收藏
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Co-delivery of the NKT agonist -galactosylceramide and tumor antigens to cross-priming dendritic cells breaks tolerance to self-antigens and promotes antitumor responses Ghinnagow, Reem; De Meester, Julie; Cruz, Luis Javier; Aspord, Caroline; Corgnac, Stephanie; Macho-Fernandez, Elodie; Soulard, Daphnee; Fontaine, Josette; Chaperot, Laurence; Charles, Julie; Soncin, Fabrice; Mami-Chouaib, Fathia; Plumas, Joel; Faveeuw, Christelle; Trottein, Francois 分享 收藏
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Epigenetic regulator CXXC5 recruits DNA demethylase Tet2 to regulate TLR7/9-elicited IFN response in pDCs Ma, Shixin; Wan, Xiaoling; Deng, Zihou; Shi, Lei; Hao, Congfang; Zhou, Zhenyuan; Zhou, Chun; Fang, Yiyuan; Liu, Jinghua; Yang, Jing; Chen, Xia; Li, Tiantian; Zang, Aiping; Yin, Shigang; Li, Bin; Plumas, Joel; Chaperot, Laurence; Zhang, Xiaoming; Xu, Guoliang; Jiang, Lubin; Shen, Nan; Xiong, Sidong; Gao, Xiaoming; Zhang, Yan; Xiao, Hui 分享 收藏
Systemic Delivery of Tumor-Targeted Bax-Derived Membrane-Active Peptides for the Treatment of Melanoma Tumors in a Humanized SCID Mouse Model Karageorgis, Anastassia; Claron, Michael; Juge, Romain; Aspord, Caroline; Thoreau, Fabien; Leloup, Claire; Kucharczak, Jerome; Plumas, Joel; Henry, Maxime; Hurbin, Amandine; Verdie, Pascal; Martinez, Jean; Subra, Gilles; Dumy, Pascal; Boturyn, Didier; Aouacheria, Abdel; Coll, Jean-Luc 分享 收藏
Tartrate-Resistant Acid Phosphatase Deficiency in the Predisposition to Systemic Lupus Erythematosus An, Jie; Briggs, Tracy A.; Dumax-Vorzet, Audrey; Alarcon-Riquelme, Marta E.; Belot, Alexandre; Beresford, Michael; Bruce, Ian N.; Carvalho, Claudia; Chaperot, Laurence; Frostegard, Johan; Plumas, Joel; Rice, Gillian I.; Vyse, Timothy J.; Wiedeman, Alice; Crow, Yanick J.; Elkon, Keith B. 分享 收藏
NFATC3 promotes IRF7 transcriptional activity in plasmacytoid dendritic cells Bao, Musheng; Wang, York; Liu, Ying; Shi, Peiqing; Lu, Hongbo; Sha, Wenwen; Weng, Leiyun; Hanabuchi, Shino; Qin, Jun; Plumas, Joel; Chaperot, Laurence; Zhang, Zhiqiang; Liu, Yong-Jun 分享 收藏
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