Pinzhu Huang

Harvard University

H指数:19

被引数:1,320

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A novel cell-permeable LOXL2 inhibitor PAT-1251 potently suppresses biliary liver fibrosis via collagen crosslinking-dependent and -independent mechanisms

一种新型细胞通透性LOXL2抑制剂PAT-1251通过依赖和不依赖胶原交联的机制有效抑制胆汁性肝纤维化

Hepatology Communications

IF4.6

2026-01-011

PRE

Is neoadjuvant chemoradiotherapy necessary for locally advanced rectal cancer above the anterior peritoneal reflection?

对于位于腹膜反折之上的局部晚期直肠癌，新辅助化放疗是否必要？

Future Oncology

IF2.6

2025-11-100

PRE

CD103-Positive Tumor-Infiltrating Lymphocytes Predict a Favorable Prognosis in Colorectal Cancer with Liver Metastasis

CD103阳性肿瘤浸润淋巴细胞预示肝转移性结直肠癌预后良好

Annals of Surgical Oncology

IF3.5

2025-11-060

PRE

Single-cell atlas of human liver and blood immune cells across fatty liver disease stages reveals distinct signatures linked to liver dysfunction and fibrogenesis

人类肝脏和血液免疫细胞在脂肪肝疾病各阶段的单细胞图谱揭示了与肝功能障碍和纤维化生成相关的独特特征

Nature Immunology

IF27.6

2025-08-290

PRE

A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients

单核和空间转录组图谱揭示了COVID-19患者肝脏中的拓扑结构、功能及再生性器官损伤

GENOME BIOLOGY

IF9.4

2025-03-142

Pita-Juarez, Yered; Karagkouni, Dimitra; Kalavros, Nikolaos; Melms, Johannes C.; Niezen, Sebastian; Delorey, Toni M.; Essene, Adam L.; Brook, Olga R.; Pant, Deepti; Skelton-Badlani, Disha; Naderi, Pourya; Huang, Pinzhu; Pan, Liuliu; Hether, Tyler; Andrews, Tallulah S.; Ziegler, Carly G. K.; Reeves, Jason; Myloserdnyy, Andriy; Chen, Rachel; Nam, Andy; Phelan, Stefan; Liang, Yan; Gregory, Mark; He, Shanshan; Patrick, Michael; Rane, Tushar; Wardhani, Aster; Amin, Amit Dipak; Biermann, Jana; Hibshoosh, Hanina; Veregge, Molly; Kramer, Zachary; Jacobs, Christopher; Yalcin, Yusuf; Phillips, Devan; Slyper, Michal; Subramanian, Ayshwarya; Ashenberg, Orr; Bloom-Ackermann, Zohar; Tran, Victoria M.; Gomez, James; Sturm, Alexander; Zhang, Shuting; Fleming, Stephen J.; Warren, Sarah; Beechem, Joseph; Hung, Deborah; Babadi, Mehrtash; Padera Jr, Robert F.; Macparland, Sonya A.; Bader, Gary D.; Imad, Nasser; Solomon, Isaac H.; Miller, Eric; Riedel, Stefan; Porter, Caroline B. M.; Villani, Alexandra-Chloe; Tsai, Linus T. -Y.; Hide, Winston; Szabo, Gyongyi; Hecht, Jonathan; Rozenblatt-Rosen, Orit; Shalek, Alex K.; Izar, Benjamin; Popov, Yury V.; Jiang, Z. Gordon; Vlachos, Ioannis S.

Contrast-enhanced intraoperative ultrasound improved hepatic recurrence-free survival in initially unresectable colorectal cancer liver metastases

DIGESTIVE AND LIVER DISEASE

IF3.8

2025-02-010

PRE

Transposon-based oncogene integration in Abcb4(Mdr2)-/-mice recapitulates high susceptibility to cholangiocarcinoma in primary sclerosing cholangitis

基于转座子的癌基因整合在Abcb4(Mdr2)-/-小鼠中重现了原发性硬化性胆管炎对胆管癌的高易感性。

JOURNAL OF HEPATOLOGY

IF33

2025-01-010

OAAI

Tinengotinib (TT-00420) in combination with atezolizumab (atezo) in Chinese patients (pts) with biliary tract carcinoma (BTC): Efficacy and safety results from a phase Ib/II study