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林

林慧 (Hui-Yi Lin)

Xian Jiaotong University
H指数:60
被引数:1.4万

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Polygenic risk score with KLK3 SNP-SNP interaction pairs for predicting prostate cancer aggressiveness

基于KLK3 SNP-SNP相互作用对的遗传风险评分预测前列腺癌侵袭性

Communications Medicine
IF6.3
2026-05-280
OAAI
Hui-Yi Lin; Indrani Sarkar; Harun Mazumder; Po-Yu Huang; Kenneth R. Muir; Johanna Schleutker; Nora Pashayan; Jyotsna Batra; David E. Neal; Henrik Grönberg; Sune F. Nielsen; Børge G. Nordestgaard; Catherine M. Tangen; Robert J. MacInnis; Alicja Wolk; Demetrius Albanes; Ruth C. Travis; Janet L. Stanford; Lorelei A. Mucci; Adam S. Kibel; Olivier Cussenot; Sonja I. Berndt; Stella Koutros; Karina Dalsgaard Sørensen; Cezary Cybulski; Eli Marie Grindedal; Josef Hoegel; Christiane Maier; Robert J. Hamilton; Barry S. Rosenstein; Ana Vega; Manolis Kogevinas; Fredrik Wiklund; Kathryn L. Penney; Manuel R. Teixeira; Hermann Brenner; Esther M. John; Radka Kaneva; Christopher J. Logothetis; Susan L. Neuhausen; Kim De Ruyck; Piet Ost; Marija Gamulin; Nawaid Usmani; Frank Claessens; Jose Esteban Castelao; Paul A. Townsend; Zsofia Kote-Jarai; Christopher A. Haiman; Rosalind A. Eeles; Jong Y. Park
Mitochondrial fatty acid oxidation as the target for blocking therapy-resistance and inhibiting tumor recurrence: The proof-of-principle model demonstrated for ovarian cancer cells

线粒体脂肪酸氧化作为阻断疗法抗性并抑制肿瘤复发的靶点：针对卵巢癌细胞的原理验证模型

Journal of Advanced Research
IF13
2025-03-170
OAAI
Hui Lin; Lingfang Wang; Hanwen Chen; Yuqing Shen; Conghui Wang; Yite Xue; Zhi Zheng; Yanan Zhang; Dajing Xia; Yihua Wu; Fenfen Wang; Xiao Li; Xiaodong Cheng; ·Hui Wang; Junfen Xu; Weiguo Lu
Cluster effect for SNP-SNP interaction pairs for predicting complex traits

预测复杂性状的snp-snp相互作用对的聚类效应

SCIENTIFIC REPORTS
IF3.9
2024-08-120
OAAI
Lin, Hui-Yi; Mazumder, Harun; Sarkar, Indrani; Huang, Po-Yu; Eeles, Rosalind A.; Kote-Jarai, Zsofia; Muir, Kenneth R.; Schleutker, Johanna; Pashayan, Nora; Batra, Jyotsna; Neal, David E.; Nielsen, Sune F.; Nordestgaard, Borge G.; Groenberg, Henrik; Wiklund, Fredrik; Macinnis, Robert J.; Haiman, Christopher A.; Travis, Ruth C.; Stanford, Janet L.; Kibel, Adam S.; Cybulski, Cezary; Khaw, Kay-Tee; Maier, Christiane; Thibodeau, Stephen N.; Teixeira, Manuel R.; Cannon-Albright, Lisa; Brenner, Hermann; Kaneva, Radka; Pandha, Hardev; Park, Jong Y.
Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants

通过多祖先全基因组发现187种新的风险变异来表征前列腺癌风险

NATURE GENETICS
IF31.8
2023-11-0928
OA
Wang, Anqi; Shen, Jiayi; Rodriguez, Alex A.; Saunders, Edward J.; Chen, Fei; Janivara, Rohini; Darst, Burcu F.; Sheng, Xin; Xu, Yili; Chou, Alisha J.; Benlloch, Sara; Dadaev, Tokhir; Brook, Mark N.; Plym, Anna; Sahimi, Ali; Hoffman, Thomas J.; Takahashi, Atushi; Matsuda, Koichi; Momozawa, Yukihide; Fujita, Masashi; Laisk, Triin; Figueredo, Jessica; Muir, Kenneth; Ito, Shuji; Liu, Xiaoxi; Uchio, Yuji; Kubo, Michiaki; Kamatani, Yoichiro; Lophatananon, Artitaya; Wan, Peggy; Andrews, Caroline; Lori, Adriana; Choudhury, Parichoy P.; Schleutker, Johanna; Tammela, Teuvo L. J.; Sipeky, Csilla; Auvinen, Anssi; Giles, Graham G.; Southey, Melissa C.; MacInnis, Robert J.; Cybulski, Cezary; Wokolorczyk, Dominika; Lubinski, Jan; Rentsch, Christopher T.; Cho, Kelly; Mcmahon, Benjamin H.; Neal, David E.; Donovan, Jenny L.; Hamdy, Freddie C.; Martin, Richard M.; Nordestgaard, Borge G.; Nielsen, Sune F.; Weischer, Maren; Bojesen, Stig E.; Roder, Andreas; Stroomberg, Hein V.; Batra, Jyotsna; Chambers, Suzanne; Horvath, Lisa; Clements, Judith A.; Tilly, Wayne; Risbridger, Gail P.; Gronberg, Henrik; Aly, Markus; Szulkin, Robert; Eklund, Martin; Nordstrom, Tobias; Pashayan, Nora; Dunning, Alison M.; Ghoussaini, Maya; Travis, Ruth C.; Key, Tim J.; Riboli, Elio; Park, Jong Y.; Sellers, Thomas A.; Lin, Hui-Yi; Albanes, Demetrius; Weinstein, Stephanie; Cook, Michael B.; Mucci, Lorelei A.; Giovannucci, Edward; Lindstrom, Sara; Kraft, Peter; Hunter, David J.; Penney, Kathryn L.; Turman, Constance; Tangen, Catherine M.; Goodman, Phyllis J.; Thompson, Ian M., Jr.; Hamilton, Robert J.; Fleshner, Neil E.; Finelli, Antonio; Parent, Marie-Elise; Stanford, Janet L.; Ostrander, Elaine A.; Koutros, Stella; Freeman, Laura E. Beane; Stampfer, Meir; Wolk, Alicja; Hakansson, Niclas; Andriole, Gerald L.; Hoover, Robert N.; Machiela, Mitchell J.; Sorensen, Karina Dalsgaard; Borre, Michael; Blot, William J.; Zheng, Wei; Yeboah, Edward D.; Mensah, James E.; Lu, Yong-Jie; Zhang, Hong-Wei; Feng, Ninghan; Mao, Xueying; Wu, Yudong; Zhao, Shan-Chao; Sun, Zan; Thibodeau, Stephen N.; McDonnell, Shannon K.; Schaid, Daniel J.; West, Catharine M. L.; Barnett, Gill; Maier, Christiane; Schnoeller, Thomas; Luedeke, Manuel; Kibel, Adam S.; Drake, Bettina F.; Cussenot, Olivier; Cancel-Tassin, Geraldine; Menegaux, Florence; Truong, Therese; Koudou, Yves Akoli; John, Esther M.; Grindedal, Eli Marie; Maehle, Lovise; Khaw, Kay-Tee; Ingles, Sue A.; Stern, Mariana C.; Vega, Ana; Gomez-Caamano, Antonio; Fachal, Laura; Rosenstein, Barry S.; Kerns, Sarah L.; Ostrer, Harry; Teixeira, Manuel R.; Paulo, Paula; Brandao, Andreia; Watya, Stephen; Lubwama, Alexander; Bensen, Jeannette T.; Butler, Ebonee N.; Mohler, James L.; Taylor, Jack A.; Kogevinas, Manolis; Dierssen-Sotos, Trinidad; Castano-Vinyals, Gemma; Cannon-Albright, Lisa; Teerlink, Craig C.; Huff, Chad D.; Pilie, Patrick; Yu, Yao; Bohlender, Ryan J.; Gu, Jian; Strom, Sara S.; Multigner, Luc; Blanchet, Pascal; Brureau, Laurent; Kaneva, Radka; Slavov, Chavdar; Mitev, Vanio; Leach, Robin J.; Brenner, Hermann; Chen, Xuechen; Holleczek, Bernd; Schoettker, Ben; Klein, Eric A.; Hsing, Ann W.; Kittles, Rick A.; Murphy, Adam B.; Logothetis, Christopher J.; Kim, Jeri; Neuhausen, Susan L.; Steele, Linda; Ding, Yuan Chun; Isaacs, William B.; Nemesure, Barbara; Hennis, Anselm J. M.; Carpten, John; Pandha, Hardev; Michael, Agnieszka; De Ruyck, Kim; De Meerleer, Gert; Ost, Piet; Xu, Jianfeng; Razack, Azad; Lim, Jasmine; Teo, Soo-Hwang; Newcomb, Lisa F.; Lin, Daniel W.; Fowke, Jay H.; Neslund-Dudas, Christine M.; Rybicki, Benjamin A.; Gamulin, Marija; Lessel, Davor; Kulis, Tomislav; Usmani, Nawaid; Abraham, Aswin; Singhal, Sandeep; Parliament, Matthew; Claessens, Frank; Joniau, Steven; Van den Broeck, Thomas; Gago-Dominguez, Manuela; Castelao, Jose Esteban; Martinez, Maria Elena; Larkin, Samantha; Townsend, Paul A.; Aukim-Hastie, Claire; Bush, William S.; Aldrich, Melinda C.; Crawford, Dana C.; Srivastava, Shiv; Cullen, Jennifer; Petrovics, Gyorgy; Casey, Graham; Wang, Ying; Tettey, Yao; Lachance, Joseph; Tang, Wei; Biritwum, Richard B.; Adjei, Andrew A.; Tay, Evelyn; Truelove, Ann; Niwa, Shelley; Yamoah, Kosj; Govindasami, Koveela; Chokkalingam, Anand P.; Keaton, Jacob M.; Hellwege, Jacklyn N.; Clark, Peter E.; Jalloh, Mohamed; Gueye, Serigne M.; Niang, Lamine; Ogunbiyi, Olufemi; Shittu, Olayiwola; Amodu, Olukemi; Adebiyi, Akindele O.; Aisuodionoe-Shadrach, Oseremen I.; Ajibola, Hafees O.; Jamda, Mustapha A.; Oluwole, Olabode P.; Nwegbu, Maxwell; Adusei, Ben; Mante, Sunny; Darkwa-Abrahams, Afua; Diop, Halimatou; Gundell, Susan M.; Roobol, Monique J.; Jenster, Guido; van Schaik, Ron H. N.; Hu, Jennifer J.; Sanderson, Maureen; Kachuri, Linda; Varma, Rohit; McKean-Cowdin, Roberta; Torres, Mina; Preuss, Michael H.; Loos, Ruth J. F.; Zawistowski, Matthew; Zollner, Sebastian; Lu, Zeyun; Van Den Eeden, Stephen K.; Easton, Douglas F.; Ambs, Stefan; Edwards, Todd L.; Magi, Reedik; Rebbeck, Timothy R.; Fritsche, Lars; Chanock, Stephen J.; Berndt, Sonja I.; Wiklund, Fredrik; Nakagawa, Hidewaki; Witte, John S.; Gaziano, J. Michael; Justice, Amy C.; Mancuso, Nick; Terao, Chikashi; Eeles, Rosalind A.; Kote-Jarai, Zsofia; Madduri, Ravi K.; Conti, David V.; Haiman, Christopher A.

研究方向

代谢性疾病GPCR新靶点的探索与机制解析骨代谢疾病GPCR靶向干预分子机制牙周炎及相关口腔疾病的GPCR靶点发现及干预策略口腔基础医学骨骼与代谢性疾病中G蛋白偶联受体（GPCR）靶点的发现与调控机制类固醇激素及内源性代谢分子的膜受体代谢性疾病和骨骼发育中的调控机制靶向干预策略粘附GPCR变构纳米抗体的开发及治疗潜力CCKBR通路选择性偏向性激动阿尔茨海默病治疗结构生物学G蛋白偶联受体ADGRG2孕激素激活GPR126乳腺癌发展Gi通路生物物理学
T
Thomas A. Sellers
H 指数:95论文数:763被引数:3.3万
J
Jong Y. Park
H 指数:54论文数:410被引数:1.1万
P
Paul D.P. Pharoah
H 指数:150论文数:1,771被引数:9.6万
H
Hermann Brenner
H 指数:202论文数:3,279被引数:32.3万
R
Rosalind A. Eeles
H 指数:136论文数:1,135被引数:8.8万
B
Børge G. Nordestgaard
H 指数:192论文数:1,788被引数:16.4万
C
Cezary Cybulski
H 指数:67论文数:629被引数:2.0万
J
Johanna Schleutker
H 指数:64论文数:378被引数:2.6万
A
Anna R. Giuliano
H 指数:85论文数:687被引数:3.0万
E
Ellen L. Goode
H 指数:82论文数:991被引数:2.8万