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Antimicrobial activity, membrane interaction and structural features of short arginine-rich antimicrobial peptides 富含精氨酸的短抗菌肽的抗菌活性、膜相互作用和结构特征 Agrillo, Bruna; Porritiello, Alessandra; Gratino, Lorena; Balestrieri, Marco; Proroga, Yolande Therese; Mancusi, Andrea; Cozzi, Loredana; Vicenza, Teresa; Dardano, Principia; Miranda, Bruno; Escriba, Pablo V.; Gogliettino, Marta; Palmieri, Gianna 分享 收藏
A Phase 1/2A trial of idroxioleic acid: first-in-class sphingolipid regulator and glioma cell autophagy inducer with antitumor activity in refractory glioma idroxioleic acid的1/2A期试验: 在难治性神经胶质瘤中具有抗肿瘤活性的一流鞘脂调节剂和神经胶质瘤细胞自噬诱导剂 Lopez, Juanita; Lai-Kwon, Julia; Molife, Rhoda; Welsh, Liam; Tunariu, Nina; Roda, Desamparados; Fernandez-Garcia, Paula; Llado, Victoria; McNicholl, Adrian G.; Rossello, Catalina A.; Taylor, Richard J.; Azaro, Analia; Rodon, Jordi; Sludden, Julieann; Veal, Gareth J.; Plummer, Ruth; Urruticoechea, Ander; Lahuerta, Ainhara; Mujika, Karmele; Escriba, Pablo V. 分享 收藏
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Multifaceted Analyses of Isolated Mitochondria Establish the Anticancer Drug 2-Hydroxyoleic Acid as an Inhibitor of Substrate Oxidation and an Activator of Complex IV-Dependent State 3 Respiration Mishra, Kumudesh; Peter, Maria; Nardiello, Anna Maria; Keller, Guy; Llado, Victoria; Fernandez-Garcia, Paula; Kahlert, Ulf D.; Barasch, Dinorah; Saada, Ann; Torok, Zsolt; Balogh, Gabor; Escriba, Pablo V.; Piotto, Stefano; Kakhlon, Or 分享 收藏
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Lipids in Pathophysiology and Development of the Membrane Lipid Therapy: New Bioactive Lipids 病理生理学中的脂质和膜脂质疗法的发展: 新的生物活性脂质 Torres, Manuel; Parets, Sebastia; Fernandez-Diaz, Javier; Beteta-Gobel, Roberto; Rodriguez-Lorca, Raquel; Roman, Ramon; Llado, Victoria; Rossello, Catalina A.; Fernandez-Garcia, Paula; Escriba, Pablo V. 分享 收藏
Safety of idroxioleic acid in combination with standard of care (temozolomide and/or radiation therapy) in newly diagnosed glioblastoma patients: A phase Ib trial Balana, C.; del Barco Berron, S.; Stradella, A.; Villanueva Vazquez, R.; Cuesta, A.; Torres, J. V.; Roma, J.; Taylor, R.; Escriba, P. V.; Llobet, E.; McNicholl, A. G. 分享 收藏
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Minerval (2-hydroxyoleic acid) causes cancer cell selective toxicity by uncoupling oxidative phosphorylation and compromising bioenergetic compensation capacity Massalha, Wessal; Markovits, Mark; Pichinuk, Edward; Feinstein-Rotkopf, Yael; Tarshish, Mark; Mishra, Kumudesh; Llado, Victoria; Weil, Miguel; Escriba, Pablo V.; Kakhlon, Or 分享 收藏
Guaiacol as a drug candidate for treating adult polyglucosan body disease Kakhlon, Or; Ferreira, Igor; Solmesky, Leonardo J.; Khazanov, Netaly; Lossos, Alexander; Alvarez, Rafael; Yetil, Deniz; Pampou, Sergey; Weil, Miguel; Senderowitz, Hanoch; Escriba, Pablo; Yue, Wyatt W.; Akman, H. Orhan 分享 收藏
Triacylglycerol mimetics regulate membrane interactions of glycogen branching enzyme: implications for therapy Alvarez, Rafael; Casas, Jesus; Lopez, David J.; Ibarguren, Maitane; Suari-Rivera, Ariadna; Teres, Silvia; Guardiola-Serrano, Francisca; Lossos, Alexander; Busquets, Xavier; Kakhlon, Or; Escriba, Pablo V. 分享 收藏
2-hydroxyoleic acid (2-OHOA), a novel activator of sphingomyelin synthase with antitumor activity in refractory glioblastoma: results of the first-in-human dose-escalation (DE) study in patients with advanced solid tumors (AST) and refractory gliomas/glioblastomas Lopez, Juanita S.; Fontes, Mariane; Coleman, Niamh; Azar, Analia; Drew, Yvette; Escriba, Pablo; Busquets, Xavier; Veal, Gareth; Tur, Vicenc; Perier, Antoine; Sicart, Elisabet; Molife, Rhoda; Plummer, Ruth; Rodon, Jordi 分享 收藏
G protein-membrane interactions I: Gαi1 myristoyl and palmitoyl modifications in protein-lipid interactions and its implications in membrane microdomain localization (vol 1851, pg 1511, 2015) Alvarez, Rafael; Lopez, David J.; Casas, Jesus; Llado, Victoria; Higuera, Monica; Nagy, Tuende; Barcelo, Miguel; Busquets, Xavier; Escriba, Pablo V. 分享 收藏