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Multicomponent Lipid Nanoparticles for RNA Transfection Gretskaya, Nataliya; Akimov, Mikhail; Andreev, Dmitry; Zalygin, Anton; Belitskaya, Ekaterina; Zinchenko, Galina; Fomina-Ageeva, Elena; Mikhalyov, Ilya; Vodovozova, Elena; Bezuglov, Vladimir 分享 收藏
Co-delivery of paclitaxel and etoposide prodrug by human serum albumin and PLGA nanoparticles: synergistic cytotoxicity in brain tumour cells 通过人血清白蛋白和PLGA纳米颗粒共递送紫杉醇和依托泊苷前药: 在脑肿瘤细胞中的协同细胞毒性 Kovshova, Tatyana; Mantrov, Sergey; Boiko, Svetlana; Malinovskaya, Julia; Merkulova, Maria; Osipova, Nadezhda; Moiseeva, Natalia; Akimov, Mikhail; Dudina, Polina; Senchikhin, Ivan; Ermolenko, Yulia; Gelperina, Svetlana 分享 收藏
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In Vivo Targeted Metabolomic Profiling of Prostanit, a Novel Anti-PAD NO-Donating Alprostadil-Based Drug Shestakova, Ksenia M.; Moskaleva, Natalia E.; Mesonzhnik, Natalia, V; Kukharenko, Alexey, V; Serkov, Igor, V; Lyubimov, Igor I.; Fomina-Ageeva, Elena, V; Bezuglov, Vladimir V.; Akimov, Mikhail G.; Appolonova, Svetlana A. 分享 收藏
Capmatinib in MET Exon 14-Mutated or MET-Amplified Non-Small-Cell Lung Cancer 卡马替尼在MET外显子14突变或MET扩增的非小细胞肺癌中的应用 Wolf, Juergen; Seto, Takashi; Han, Ji-Youn; Reguart, Noemi; Garon, Edward B.; Groen, Harry J. M.; Tan, Daniel S. W.; Hida, Toyoaki; de Jonge, Maja; Orlov, Sergey V.; Smit, Egbert F.; Souquet, Pierre-Jean; Vansteenkiste, Johan; Hochmair, Maximilian; Felip, Enriqueta; Nishio, Makoto; Thomas, Michael; Ohashi, Kadoaki; Toyozawa, Ryo; Overbeck, Tobias R.; de Marinis, Filippo; Kim, Tae-Min; Laack, Eckart; Robeva, Anna; Le Mouhaer, Sylvie; Waldron-Lynch, Maeve; Sankaran, Banu; Balbin, O. Alejandro; Cui, Xiaoming; Giovannini, Monica; Akimov, Mikhail; Heist, Rebecca S. 分享 收藏
Novel bexarotene derivatives: Synthesis and cytotoxicity evaluation for glioma cells in 2D and 3D in vitro models 新型bexarotene衍生物: 2D和3D体外模型中神经胶质瘤细胞的合成和细胞毒性评估 Gretskaya, Natalia M.; Gamisonia, Alina M.; Dudina, Polina, V; Zakharov, Stanislav S.; Sherstyanykh, Galina; Akasov, Roman; Burov, Sergey; Serkov, Igor, V; Akimov, Mikhail G.; Bezuglov, Vladimir V.; Markvicheva, Elena 分享 收藏
Capmatinib in patients with METex14-mutated advanced non-small cell lung cancer who received prior immunotherapy: The phase II GEOMETRY mono-1 study Vansteenkiste, J. F.; Smit, E. F.; Groen, H. J. M.; Garon, E. B.; Heist, R. S.; Hida, T.; Nishio, M.; Kokowski, K.; Grohe, C.; Reguart, N.; Mansfield, A. S.; Robeva, A.; Ghebremariam, S.; Waldron-Lynch, M.; Akimov, M.; Nwana, N.; Giovannini, M.; Wolf, J. 分享 收藏
Molecular correlates of response to capmatinib in advanced non-small-cell lung cancer: clinical and biomarker results from a phase I trial Schuler, M.; Berardi, R.; Lim, W-T; de Jonge, M.; Bauer, T. M.; Azaro, A.; Gottfried, M.; Han, J-Y; Lee, D. H.; Wollner, M.; Hong, D. S.; Vogel, A.; Delmonte, A.; Akimov, M.; Ghebremariam, S.; Cui, X.; Nwana, N.; Giovannini, M.; Kim, T. M. 分享 收藏
Biomarker analysis of patients with METΔex14 mutated non small-cell lung cancer (NSCLC) treated with capmatinib in the GEOMETRY mono-1 study Heist, Rebecca S.; Garon, Edward B.; Tan, Daniel S. W.; Groen, Harry J. M.; Seto, Takashi; Smit, Egbert F.; Fairchild, Lauren; Balbin, Alejandro; Yan, Ming; Giovannini, Monica; Akimov, Mikhail; Sankaran, Banu; Nwana, Ngozi; Wolf, Juergen 分享 收藏
Ocular toxicity of AUY922 in pigmented and albino rats AUY922对色素沉着和白化病大鼠的眼毒性 Roman, Danielle; VerHoeve, James; Schadt, Heiko; Vicart, Axel; Walker, Ursula Junker; Turner, Oliver; Richardson, Terrilyn A.; Wolford, Suzanne T.; Miller, Paul E.; Zhou, Wei; Lu, Hong; Akimov, Mikhail; Kluwe, William 分享 收藏
Comprehensive genomic profiling of advanced cancers identifies MET exon 14 alterations that are sensitive to MET inhibitors Frampton, G.; Ali, S.; Rosenzweig, M.; Chmielecki, J.; Bauer, T.; Akimov, M.; Peters, M.; Bufill, J.; Lee, C.; Ou, I.; Salgia, R.; Yelensky, R.; Morosini, D.; Ross, J.; Philip, S.; Miller, V. 分享 收藏
Activation of MET via Diverse Exon 14 Splicing Alterations Occurs in Multiple Tumor Types and Confers Clinical Sensitivity to MET Inhibitors Frampton, Garrett M.; Ali, Siraj M.; Rosenzweig, Mark; Chmielecki, Juliann; Lu, Xinyuan; Bauer, Todd M.; Akimov, Mikhail; Bufill, Jose A.; Lee, Carrie; Jentz, David; Hoover, Rick; Ou, Sai-Hong Ignatius; Salgia, Ravi; Brennan, Tim; Chalmers, Zachary R.; Jaeger, Savina; Huang, Alan; Elvin, Julia A.; Erlich, Rachel; Fichtenholtz, Alex; Gowen, Kyle A.; Greenbowe, Joel; Johnson, Adrienne; Khaira, Depinder; McMahon, Caitlin; Sanford, Eric M.; Roels, Steven; White, Jared; Greshock, Joel; Schlegel, Robert; Lipson, Doron; Yelensky, Roman; Morosini, Deborah; Ross, Jeffrey S.; Collisson, Eric; Peters, Malte; Stephens, Philip J.; Miller, Vincent A. 分享 收藏
Phase 1/1B trial of the heat shock protein 90 inhibitor NVP-AUY922 as monotherapy or in combination with bortezomib in patients with relapsed or refractory multiple myeloma Seggewiss-Bernhardt, Ruth; Bargou, Ralf C.; Goh, Yeow Tee; Stewart, A. Keith; Spencer, Andrew; Alegre, Adrian; Blade, Joan; Ottmann, Oliver G.; Fernandez-Ibarra, Cristina; Lu, Hong; Pain, Scott; Akimov, Mikhail; Iyer, Swaminathan Padmanabhan 分享 收藏
A first-in-human phase I, dose-escalation, multicentre study of HSP990 administered orally in adult patients with advanced solid malignancies Spreafico, A.; Delord, J-P; De Mattos-Arruda, L.; Berge, Y.; Rodon, J.; Cottura, E.; Bedard, P. L.; Akimov, M.; Lu, H.; Pain, S.; Kaag, A.; Siu, L. L.; Cortes, J. 分享 收藏
Inhibition of HSP90 with AUY922 Induces Synergy in HER2-Amplified Trastuzumab-Resistant Breast and Gastric Cancer Wainberg, Zev A.; Anghel, Adrian; Rogers, Amy M.; Desai, Amrita J.; Kalous, Ondrej; Conklin, Dylan; Ayala, Raul; O'Brien, Neil A.; Quadt, Cornelia; Akimov, Mikhail; Slamon, Dennis J.; Finn, Richard S. 分享 收藏
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