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收藏分享 收藏 分享 收藏 Immunization with V987H-stabilized Spike glycoprotein protects K18-hACE2 mice and golden Syrian hamsters upon SARS-CoV-2 infectionV987H-stabilized刺突糖蛋白预防接种可保护SARS-CoV-2感染后的K18-hACE2小鼠和金叙利亚仓鼠
Avila-Nieto, Carlos; Vergara-Alert, Julia; Amengual-Rigo, Pep; Ainsua-Enrich, Erola; Brustolin, Marco; de la Concepcion, Maria Luisa Rodriguez; Pedreno-Lopez, Nuria; Rodon, Jordi; Urrea, Victor; Pradenas, Edwards; Marfil, Silvia; Ballana, Ester; Riveira-Munoz, Eva; Perez, Monica; Roca, Nuria; Tarres-Freixas, Ferran; Cantero, Guillermo; Pons-Grifols, Anna; Rovirosa, Carla; Aguilar-Gurrieri, Carmen; Ortiz, Raquel; Barajas, Ana; Trinite, Benjamin; Lepore, Rosalba; Munoz-Basagoiti, Jordana; Perez-Zsolt, Daniel; Izquierdo-Useros, Nuria; Valencia, Alfonso; Blanco, Julia; Guallar, Victor; Clotet, Bonaventura; Segales, Joaquim; Carrillo, Jorge 分享 收藏 Virus-like particle-mediated delivery of structure-selected neoantigens demonstrates immunogenicity and antitumoral activity in mice结构选择的新抗原的病毒样颗粒介导的递送在小鼠中显示出免疫原性和抗肿瘤活性Barajas, Ana; Amengual-Rigo, Pep; Pons-Grifols, Anna; Ortiz, Raquel; Carmona, Oriol Gracia; Urrea, Victor; de la Iglesia, Nuria; Blanco-Heredia, Juan; Anjos-Souza, Carla; Varela, Ismael; Trinite, Benjamin; Tarres-Freixas, Ferran; Rovirosa, Carla; Lepore, Rosalba; Vazquez, Miguel; de Mattos-Arruda, Leticia; Valencia, Alfonso; Clotet, Bonaventura; Aguilar-Gurrieri, Carmen; Guallar, Victor; Carrillo, Jorge; Blanco, Julia 分享 收藏 Novel Spike-stabilized trimers with improved production protect K18-hACE2 mice and golden Syrian hamsters from the highly pathogenic SARS-CoV-2 Beta variant具有改善产量的新型尖峰稳定三聚体可保护K18-hACE2小鼠和金色叙利亚仓鼠免受高致病性SARS-CoV-2 β 变体的侵害Avila-Nieto, Carlos; Vergara-Alert, Julia; Amengual-Rigo, Pep; Ainsua-Enrich, Erola; Brustolin, Marco; de la Concepcion, Maria Luisa Rodriguez; Pedreno-Lopez, Nuria; Rodon, Jordi; Urrea, Victor; Pradenas, Edwards; Marfil, Silvia; Ballana, Ester; Riveira-Munoz, Eva; Perez, Monica; Roca, Nuria; Tarres-Freixas, Ferran; Carabelli, Julieta; Cantero, Guillermo; Pons-Grifols, Anna; Rovirosa, Carla; Aguilar-Gurrieri, Carmen; Ortiz, Raquel; Barajas, Ana; Trinite, Benjamin; Lepore, Rosalba; Munoz-Basagoiti, Jordana; Perez-Zsolt, Daniel; Izquierdo-Useros, Nuria; Valencia, Alfonso; Blanco, Julia; Clotet, Bonaventura; Guallar, Victor; Segales, Joaquim; Carrillo, Jorge 分享 收藏 Epitope-engineered human hematopoietic stem cells are shielded from CD123-targeted immunotherapy表位工程化的人造血干细胞免受CD123-targeted免疫疗法的影响Marone, Romina; Landmann, Emmanuelle; Devaux, Anna; Lepore, Rosalba; Seyres, Denis; Zuin, Jessica; Burgold, Thomas; Engdahl, Corinne; Capoferri, Giuseppina; Dell'Aglio, Alessandro; Larrue, Clement; Simonetta, Federico; Rositzka, Julia; Rhiel, Manuel; Andrieux, Geoffroy; Gallagher, Danielle N.; Schroder, Markus S.; Wiederkehr, Amelie; Sinopoli, Alessandro; Do Sacramento, Valentin; Haydn, Anna; Garcia-Prat, Laura; Divsalar, Christopher; Camus, Anna; Xu, Liwen; Bordoli, Lorenza; Schwede, Torsten; Porteus, Matthew; Tamburini, Jerome; Corn, Jacob E.; Cathomen, Toni; Cornu, Tatjana I.; Urlinger, Stefanie; Jeker, Lukas T. 分享 收藏 Heterogeneous Infectivity and Pathogenesis of SARS-CoV-2 Variants Beta, Delta and Omicron in Transgenic K18-hACE2 and Wildtype MiceTarres-Freixas, Ferran; Trinite, Benjamin; Pons-Grifols, Anna; Romero-Durana, Miguel; Riveira-Munoz, Eva; Avila-Nieto, Carlos; Perez, Monica; Garcia-Vidal, Edurne; Perez-Zsolt, Daniel; Munoz-Basagoiti, Jordana; Raich-Regue, Dalia; Izquierdo-Useros, Nuria; Andres, Cristina; Anton, Andres; Pumarola, Tomas; Blanco, Ignacio; Noguera-Julian, Marc; Guallar, Victor; Lepore, Rosalba; Valencia, Alfonso; Urrea, Victor; Vergara-Alert, Julia; Clotet, Bonaventura; Ballana, Ester; Carrillo, Jorge; Segales, Joaquim; Blanco, Julia 分享 收藏 Target highlights in CASP14: Analysis of models by structure providersCASP14中的目标亮点: 结构提供者对模型的分析Alexander, Leila T.; Lepore, Rosalba; Kryshtafovych, Andriy; Adamopoulos, Athanassios; Alahuhta, Markus; Arvin, Ann M.; Bomble, Yannick J.; Bottcher, Bettina; Breyton, Cecile; Chiarini, Valerio; Chinnam, Naga Babu; Chiu, Wah; Fidelis, Krzysztof; Grinter, Rhys; Gupta, Gagan D.; Hartmann, Marcus D.; Hayes, Christopher S.; Heidebrecht, Tatjana; Ilari, Andrea; Joachimiak, Andrzej; Kim, Youngchang; Linares, Romain; Lovering, Andrew L.; Lunin, Vladimir V.; Lupas, Andrei N.; Makbul, Cihan; Michalska, Karolina; Moult, John; Mukherjee, Prasun K.; Nutt, William Sam; Oliver, Stefan L.; Perrakis, Anastassis; Stols, Lucy; Tainer, John A.; Topf, Maya; Tsutakawa, Susan E.; Valdivia-Delgado, Mauricio; Schwede, Torsten 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Previous SARS-CoV-2 Infection Increases B.1.1.7 Cross-Neutralization by Vaccinated IndividualsTrinite, Benjamin; Pradenas, Edwards; Marfil, Silvia; Rovirosa, Carla; Urrea, Victor; Tarres-Freixas, Ferran; Ortiz, Raquel; Rodon, Jordi; Vergara-Alert, Julia; Segales, Joaquim; Guallar, Victor; Lepore, Rosalba; Izquierdo-Useros, Nuria; Trujillo, Gloria; Trape, Jaume; Gonzalez-Fernandez, Carolina; Flor, Antonia; Perez-Vidal, Rafel; Toledo, Ruth; Chamorro, Anna; Paredes, Roger; Blanco, Ignacio; Grau, Eulalia; Massanella, Marta; Carrillo, Jorge; Clotet, Bonaventura; Blanco, Julia 分享 收藏 Neoantigen prediction and computational perspectives towards clinical benefit: recommendations from the ESMO Precision Medicine Working GroupDe Mattos-Arruda, L.; Vazquez, M.; Finotello, F.; Lepore, R.; Porta, E.; Hundal, J.; Amengual-Rigo, P.; Ng, C. K. Y.; Valencia, A.; Carrillo, J.; Chan, T. A.; Guallar, V.; McGranahan, N.; Blanco, J.; Griffith, M. 分享 收藏 Target highlights in CASP13: Experimental target structures through the eyes of their authorsLepore, Rosalba; Kryshtafovych, Andriy; Alahuhta, Markus; Veraszto, Harshul A.; Bomble, Yannick J.; Bufton, Joshua C.; Bullock, Alex N.; Caba, Cody; Cao, Hongnan; Davies, Owen R.; Desfosses, Ambroise; Dunne, Matthew; Fidelis, Krzysztof; Goulding, Celia W.; Gurusaran, Manickam; Gutsche, Irina; Harding, Christopher J.; Hartmann, Marcus D.; Hayes, Christopher S.; Joachimiak, Andrzej; Leiman, Petr G.; Loppnau, Peter; Lovering, Andrew L.; Lunin, Vladimir V.; Michalska, Karolina; Mir-Sanchis, Ignacio; Mitra, Alok; Moult, John; Phillips, George N., Jr.; Pinkas, Daniel M.; Rice, Phoebe A.; Tong, Yufeng; Topf, Maya; Walton, Jonathan D.; Schwede, Torsten 分享 收藏 Genome-wide RNA-seq analysis indicates that the DAG1 transcription factor promotes hypocotyl elongation acting on ABA, ethylene and auxin signalingLorrai, Riccardo; Gandolfi, Francesco; Boccaccini, Alessandra; Ruta, Veronica; Possenti, Marco; Tramontano, Anna; Costantino, Paolo; Lepore, Rosalba; Vittorioso, Paola 分享 收藏 SWISS-MODEL: homology modelling of protein structures and complexes瑞士模型: 蛋白质结构和复合物的同源建模Waterhouse, Andrew; Bertoni, Martino; Bienert, Stefan; Studer, Gabriel; Tauriello, Gerardo; Gumienny, Rafal; Heer, Florian T.; de Beer, Tjaart A. P.; Rempfer, Christine; Bordoli, Lorenza; Lepore, Rosalba; Schwede, Torsten 分享 收藏 分享 收藏 分享 收藏 An expanded evaluation of protein function prediction methods shows an improvement in accuracy蛋白质功能预测方法的扩展评估显示准确性有所提高Jiang, Yuxiang; Oron, Tal Ronnen; Clark, Wyatt T.; Bankapur, Asma R.; D'Andrea, Daniel; Lepore, Rosalba; Funk, Christopher S.; Kahanda, Indika; Verspoor, Karin M.; Ben-Hur, Asa; Koo, Da Chen Emily; Penfold-Brown, Duncan; Shasha, Dennis; Youngs, Noah; Bonneau, Richard; Lin, Alexandra; Sahraeian, Sayed M. E.; Martelli, Pier Luigi; Profiti, Giuseppe; Casadio, Rita; Cao, Renzhi; Zhong, Zhaolong; Cheng, Jianlin; Altenhoff, Adrian; Skunca, Nives; Dessimoz, Christophe; Dogan, Tunca; Hakala, Kai; Kaewphan, Suwisa; Mehryary, Farrokh; Salakoski, Tapio; Ginter, Filip; Fang, Hai; Smithers, Ben; Oates, Matt; Gough, Julian; Toronen, Petri; Koskinen, Patrik; Holm, Liisa; Chen, Ching-Tai; Hsu, Wen-Lian; Bryson, Kevin; Cozzetto, Domenico; Minneci, Federico; Jones, David T.; Chapman, Samuel; Dukka, B. K. C.; Khan, Ishita K.; Kihara, Daisuke; Ofer, Dan; Rappoport, Nadav; Stern, Amos; Cibrian-Uhalte, Elena; Denny, Paul; Foulger, Rebecca E.; Hieta, Reija; Legge, Duncan; Lovering, Ruth C.; Magrane, Michele; Melidoni, Anna N.; Mutowo-Meullenet, Prudence; Pichler, Klemens; Shypitsyna, Aleksandra; Li, Biao; Zakeri, Pooya; ElShal, Sarah; Tranchevent, Leon-Charles; Das, Sayoni; Dawson, Natalie L.; Lee, David; Lees, Jonathan G.; Sillitoe, Ian; Bhat, Prajwal; Nepusz, Tamas; Romero, Alfonso E.; Sasidharan, Rajkumar; Yang, Haixuan; Paccanaro, Alberto; Gillis, Jesse; Sedeno-Cortes, Adriana E.; Pavlidis, Paul; Feng, Shou; Cejuela, Juan M.; Goldberg, Tatyana; Hamp, Tobias; Richter, Lothar; Salamov, Asaf; Gabaldon, Toni; Marcet-Houben, Marina; Supek, Fran; Gong, Qingtian; Ning, Wei; Zhou, Yuanpeng; Tian, Weidong; Falda, Marco; Fontana, Paolo; Lavezzo, Enrico; Toppo, Stefano; Ferrari, Carlo; Giollo, Manuel; Piovesan, Damiano; Tosatto, Silvio C. E.; del Pozo, Angela; Fernandez, Jose M.; Maietta, Paolo; Valencia, Alfonso; Tress, Michael L.; Benso, Alfredo; Di Carlo, Stefano; Politano, Gianfranco; Savino, Alessandro; Rehman, Hafeez Ur; Re, Matteo; Mesiti, Marco; Valentini, Giorgio; Bargsten, Joachim W.; van Dijk, Aalt D. J.; Gemovic, Branislava; Glisic, Sanja; Perovic, Vladmir; Veljkovic, Veljko; Veljkovic, Nevena; Almeida-e-Silva, Danillo C.; Vencio, Ricardo Z. N.; Sharan, Malvika; Vogel, Joerg; Kansakar, Lakesh; Zhang, Shanshan; Vucetic, Slobodan; Wang, Zheng; Sternberg, Michael J. E.; Wass, Mark N.; Huntley, Rachael P.; Martin, Maria J.; O'Donovan, Claire; Robinson, Peter N.; Moreau, Yves; Tramontano, Anna; Babbitt, Patricia C.; Brenner, Steven E.; Linial, Michal; Orengo, Christine A.; Rost, Burkhard; Greene, Casey S.; Mooney, Sean D.; Friedberg, Iddo; Radivojac, Predrag 分享 收藏 
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