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Development and validation of the Normalized Organoid Growth Rate (NOGR) metric in brightfield imaging-based assays Deben, Christophe; de la Hoz, Edgar Cardenas; Fortes, Felicia Rodrigues; Le Compte, Maxim; Seghers, Sofie; Vanlanduit, Steve; Vercammen, Hendrik; van den Bogert, Bert; Dusetti, Nelson; Lin, Abraham; Roeyen, Geert; Peeters, Marc; Prenen, Hans; Lardon, Filip; Smits, Evelien 分享 收藏
Auranofin repurposing for lung and pancreatic cancer: low CA12 expression as a marker of sensitivity in patient-derived organoids, with potentiated efficacy by AKT inhibition Deben, Christophe; Boullosa, Laurie Freire; Fortes, Felicia Rodrigues; de la Hoz, Edgar Cardenas; Le Compte, Maxim; Seghers, Sofie; Peeters, Marc; Vanlanduit, Steve; Lin, Abraham; Dijkstra, Krijn K.; Van Schil, Paul; Hendriks, Jeroen M. H.; Prenen, Hans; Roeyen, Geert; Lardon, Filip; Smits, Evelien 分享 收藏
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IL-15-secreting CAR natural killer cells directed toward the pan-cancer target CD70 eliminate both cancer cells and cancer-associated fibroblasts IL-15-secreting针对泛癌症靶标CD70的CAR自然杀伤细胞可消除癌细胞和癌症相关的成纤维细胞 van den Eynde, Astrid; Gehrcken, Laura; Verhezen, Tias; Lau, Ho Wa; Hermans, Christophe; Lambrechts, Hilde; Flieswasser, Tal; Quatannens, Delphine; Roex, Gils; Zwaenepoel, Karen; Marcq, Elly; Joye, Philippe; De La Hoz, Edgar Cardenas; Deben, Christophe; Gasparini, Alessia; Montay-Gruel, Pierre; Le Compte, Maxim; Lion, Eva; Lardon, Filip; Van Laere, Steven; Siozopoulou, Vasiliki; Campillo-Davo, Diana; De Waele, Jorrit; Pauwels, Patrick; Jacobs, Julie; Smits, Evelien; Van Audenaerde, Jonas R. M. 分享 收藏
Single-organoid analysis reveals clinically relevant treatment-resistant and invasive subclones in pancreatic cancer 单类器官分析揭示了胰腺癌中临床相关的治疗抗性和侵袭性亚克隆 Le Compte, Maxim; De La Hoz, Edgar Cardenas; Peeters, Sofia; Fortes, Felicia Rodrigues; Hermans, Christophe; Domen, Andreas; Smits, Evelien; Lardon, Filip; Vandamme, Timon; Lin, Abraham; Vanlanduit, Steve; Roeyen, Geert; Van Laere, Steven; Prenen, Hans; Peeters, Marc; Deben, Christophe 分享 收藏
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Targeting CD70 in combination with chemotherapy to enhance the anti-tumor immune effects in non-small cell lung cancer 靶向CD70联合化疗增强非小细胞肺癌抗肿瘤免疫效应 Flieswasser, Tal; van den Eynde, Astrid; Boullosa, Laurie Freire; Melis, Joeran; Hermans, Christophe; Merlin, Celine; Lau, Ho Wa; Van Audenaerde, Jonas; Lardon, Filip; Smits, Evelien; Pauwels, Patrick; Jacobs, Julie 分享 收藏
Auranofin Synergizes with the PARP Inhibitor Olaparib to Induce ROS-Mediated Cell Death in Mutant p53 Cancers Boullosa, Laurie Freire; Van Loenhout, Jinthe; Flieswasser, Tal; Hermans, Christophe; Merlin, Celine; Lau, Ho Wa; Marcq, Elly; Verschuuren, Marlies; De Vos, Winnok H.; Lardon, Filip; Smits, Evelien L. J.; Deben, Christophe 分享 收藏
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OrBITS: label-free and time-lapse monitoring of patient derived organoids for advanced drug screening OrBITS: 用于高级药物筛选的患者衍生类器官的无标签和延时监测 Deben, Christophe; de la Hoz, Edgar Cardenas; Le Compte, Maxim; Van Schil, Paul; Hendriks, Jeroen M. H.; Lauwers, Patrick; Yogeswaran, Suresh Krishan; Lardon, Filip; Pauwels, Patrick; Van Laere, Steven; Bogaerts, Annemie; Smits, Evelien; Vanlanduit, Steve; Lin, Abraham 分享 收藏
Optimization of the Solvent and In Vivo Administration Route of Auranofin in a Syngeneic Non-Small Cell Lung Cancer and Glioblastoma Mouse Model Boullosa, Laurie Freire; Van Loenhout, Jinthe; Hermans, Christophe; Lau, Ho Wa; Merlin, Celine; Marcq, Elly; Takhsha, Farnaz Sedigheh; Martinet, Wim; De Meyer, Guido R. Y.; Lardon, Filip; Smits, Evelien L. J.; Deben, Christophe 分享 收藏
The prognostic impact of the immune signature in head and neck squamous cell carcinoma 免疫标记对头颈部鳞状细胞癌预后的影响 Baysal, Hasan; Siozopoulou, Vasiliki; Zaryouh, Hannah; Hermans, Christophe; Lau, Ho Wa; Lambrechts, Hilde; Fransen, Erik; De Pauw, Ines; Jacobs, Julie; Peeters, Marc; Pauwels, Patrick; Vermorken, Jan Baptist; Smits, Evelien; Lardon, Filip; De Waele, Jorrit; Wouters, An 分享 收藏
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Prognostic implications of cellular senescence in resected non-small cell lung cancer br 切除的非小细胞肺癌中细胞衰老的预后意义 Domen, Andreas; Deben, Christophe; De Pauw, Ines; Hermans, Christophe; Lambrechts, Hilde; Verswyvel, Jasper; Siozopoulou, Vasiliki; Pauwels, Patrick; Demaria, Marco; van de Wiel, Mick; Janssens, Annelies; Hendriks, Jeroen M. H.; Van Schil, Paul; Vermorken, Jan B.; Vandamme, Timon; Prenen, Hans; Peeters, Marc; Lardon, Filip; Wouters, An 分享 收藏
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The effect of local non-thermal plasma therapy on the cancer-immunity cycle in a melanoma mouse model Lin, Abraham; De Backer, Joey; Quatannens, Delphine; Cuypers, Bart; Verswyvel, Hanne; de la Hoz, Edgar Cardenas; Ribbens, Bart; Siozopoulou, Vasiliki; van Audenaerde, Jonas; Marcq, Elly; Lardon, Filip; Laukens, Kris; Vanlanduit, Steve; Smits, Evelien; Bogaerts, Annemie 分享 收藏