未登录 Hypothalamic sex-specific metabolic shift by canagliflozin during aging Jayarathne, Hashan S. M.; Sullivan, Ryan; Stilgenbauer, Lukas; Debarba, Lucas K.; Kuchumov, Artur; Koshko, Lisa; Scofield, Sydney; Liu, Wanqing; Ginsburg, Brett C.; Miller, Richard A.; Sadagurski, Marianna 分享 收藏
Selective ITK blockade induces antitumor responses and enhances efficacy to immune checkpoint inhibitors in preclinical models Hsu, Lih-Yun; Pawar, Rahul D.; Li, Dan; Ghosh, Poorva; Nguyen, Kevin; Williams, Carlene; Song, Yuqin; Ding, Ning; Verner, Erik; Miller, Richard A. 分享 收藏
Anti-CD73 antibody activates human B cells, enhances humoral responses and induces redistribution of B cells in patients with cancer Miller, Richard A.; Luke, Jason John; Hu, Shenshen; Mahabhashyam, Suresh; Jones, William B.; Marron, Thomas; Merchan, Jaime R.; Hughes, Brett G. M.; Willingham, Stephen B. 分享 收藏
IMMUNOTHERAPY WITH B CELL ACTIVATING ANTIBODY CPI-006 IN PATIENTS (PTS) WITH MILD TO MODERATE COVID-19 STIMULATES ANTI-SARS-COV-2 ANTIBODY RESPONSE, MEMORY B CELLS AND MEMORY T EFFECTOR CELLS Criner, Gerard; Mobasher, Mehrdad; Hill, Craig; Hu, Shenshen; Mahabhashyam, Suresh; Brody, Joshua; Marron, Thomas; Willingham, Stephen; Miller, Richard 分享 收藏
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Adenosine 2A Receptor Blockade as an Immunotherapy for Treatment-Refractory Renal Cell Cancer 腺苷2A受体阻断作为治疗难治性肾细胞癌的免疫疗法 Fong, Lawrence; Hotson, Andrew; Powderly, John D.; Sznol, Mario; Heist, Rebecca S.; Choueiri, Toni K.; George, Saby; Hughes, Brett G. M.; Hellmann, Matthew D.; Shepard, Dale R.; Rini, Brian I.; Kummar, Shivaani; Weise, Amy M.; Riese, Matthew J.; Markman, Ben; Emens, Leisha A.; Mahadevan, Daruka; Luke, Jason J.; Laport, Ginna; Brody, Joshua D.; Hernandez-Aya, Leonel; Bonomi, Philip; Goldman, Jonathan W.; Berim, Lyudmyla; Renouf, Daniel J.; Goodwin, Rachel A.; Munneke, Brian; Ho, Po Y.; Hsieh, Jessica; McCaffery, Ian; Kwei, Long; Willingham, Stephen B.; Miller, Richard A. 分享 收藏
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CPI-818: A selective inhibitor of interleukin-2-inducible T-cell kinase (ITK) that inhibits T-cell receptor signaling, promotes Th1 skewing, and achieves objective tumor responses when administered to dogs with T cell lymphomas Janc, James W.; Hill, Craig M.; Ng, Patrick P.; Hoston, Andrew N.; Madriaga, Antonett; Dao-Pick, Trang P.; Yeung, Kitman S.; Hudson, Ryan; Beausoleil, Anne-Marie; Bradley, Erin; Verner, Erik; Thamm, Douglas H.; Miller, Richard A.; Buggy, Joseph J. 分享 收藏
Merkel cell polyomavirus is uncommon in New Zealand Merkel cell carcinomas Woodhouse, B.; Robb, T. J.; Hearn, J. I.; Houseman, P. S.; Hayward, G.; Miller, R.; Restall, A. P.; Findlay, M.; Lawrence, B.; Print, C. G.; Parker, K.; Blenkiron, C. 分享 收藏
Inhibition of A2AR induces anti-tumor immunity alone and in combination with anti-PD-L1 in preclinical and clinical studies Willingham, Stephen; Hotson, Andrew; Ho, Po; Choy, Carmen; Walter, Kim; Yusko, Erik; Benzeno, Sharon; Laport, Ginna; Miller, Richard; McCaffery, Ian 分享 收藏
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CPI-444, an oral adenosine A2a receptor (A2aR) antagonist, demonstrates clinical activity in patients with advanced solid tumors Emens, Leisha; Powderly, John; Fong, Lawrence; Brody, Joshua; Forde, Patrick; Hellmann, Matthew; Hughes, Brett; Kummar, Shivaani; Loi, Sherene; Luke, Jason; Mahadevan, Daruka; Markman, Benjamin; McCaffery, Ian; Miller, Richard; Laport, Ginna 分享 收藏
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Evaluation of Resveratrol, Green Tea Extract, Curcumin, Oxaloacetic Acid, and Medium-Chain Triglyceride Oil on Life Span of Genetically Heterogeneous Mice Strong, Randy; Miller, Richard A.; Astle, Clinton M.; Baur, Joseph A.; de Cabo, Rafael; Fernandez, Elizabeth; Guo, Wen; Javors, Martin; Kirkland, James L.; Nelson, James F.; Sinclair, David A.; Teter, Bruce; Williams, David; Zaveri, Nurulain; Nadon, Nancy L.; Harrison, David E. 分享 收藏
The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy 布鲁顿酪氨酸激酶抑制剂PCI-32765阻断b细胞活化,在自身免疫性疾病和b细胞恶性肿瘤模型中有效 Honigberg, Lee A.; Smith, Ashley M.; Sirisawad, Mint; Verner, Erik; Loury, David; Chang, Betty; Li, Shyr; Pan, Zhengying; Thamm, Douglas H.; Miller, Richard A.; Buggy, Joseph J. 分享 收藏
Synthesis and biologic properties of hydrophilic sapphyrins, a new class of tumor-selective inhibitors of gene expression Wang, Zhong; Lecane, Philip S.; Thiemann, Patricia; Fan, Qing; Cortez, Cecilia; Ma, Xuan; Tonev, Danielle; Miles, Dale; Naumovski, Louie; Miller, Richard A.; Magda, Darren; Cho, Dong-Gyu; Sessler, Jonathan L.; Pike, Brian L.; Yeligar, Samantha M.; Karaman, Mazen W.; Hacia, Joseph G. 分享 收藏