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Challenges in predicting outcomes for watch and wait follicular lymphoma patients: insights into clinical, pathological, and molecular factors 预测观察等待策略下滤泡性淋巴瘤患者预后的挑战:临床、病理及分子因素的见解 Hesius, Eva A. M.; Stewart, James P.; Kroeze, Leonie I.; van der Spek, Ellen; Issa, Djamila; Nooijen, Peet; Luijks, Jeroen; Gonzalez, David; Groenen, Patricia J. T. A.; van Spriel, Annemiek B.; Blijlevens, Nicole M. A.; van den Brand, Michiel; Stevens, Wendy B. C. 分享 收藏
Validation Of Next Generation Sequencing Using EuroClonality-NDC Panel In Primary Cutaneous Lymphomas and comparison with Traditional PCR Techniques Hatzakis, A.; Pugh, M.; Hock, Y. L.; Rooke, B.; Murray, D.; Alluri, U.; Shah, F.; Kashipaz, R. Amel; Vydianath, B.; de Castro, D. Gonzalez; Taniere, P.; Scarisbrick, J. 分享 收藏
Comprehensive genetic analysis by targeted sequencing identifies risk factors and predicts patient outcome in Mantle Cell Lymphoma: results from the EU-MCL network trials Khouja, Mouhamad; Jiang, Linmiao; Pal, Karol; Stewart, Peter James; Regmi, Binaya; Schwarz, Martin; Klapper, Wolfram; Alig, Stefan K.; Darzentas, Nikos; Kluin-Nelemans, Hanneke C.; Hermine, Olivier; Dreyling, Martin; de Castro, David Gonzalez; Hoster, Eva; Pott, Christiane 分享 收藏
Nilotinib in KIT-driven advanced melanoma: Results from the phase II single-arm NICAM trial 尼洛替尼治疗试剂盒驱动的晚期黑色素瘤: II期单臂NICAM试验的结果 Larkin, James; Marais, Richard; Porta, Nuria; de Castro, David Gonzalez; Parsons, Lisa; Messiou, Christina; Stamp, Gordon; Thompson, Lisa; Edmonds, Kim; Sarker, Sarah; Banerji, Jane; Lorigan, Paul; Evans, Thomas R. Jeffry; Corrie, Pippa; Marshall, Ernest; Middleton, Mark R.; Nathan, Paul; Nicholson, Steve; Ottensmeier, Christian; Plummer, Ruth; Bliss, Judith; Valpione, Sara; Turajlic, Samra 分享 收藏
TP53 Mutations Identified Using NGS Comprise the Overwhelming Majority of TP53 Disruptions in CLL: Results From a Multicentre Study Catherwood, Mark A.; Wren, Dorte; Chiecchio, Laura; Cavalieri, Doriane; Donaldson, David; Lawless, Sarah; ElHassadi, Ezzat; Hayat, Amjad; Cahill, Mary R.; O'Shea, Derville; Sargent, Jeremy; Stewart, Peter; Maurya, Manisha; Quinn, John; Murphy, Philip; de Castro, David Gonzalez; Mills, Ken; Cross, Nicholas C. P.; Forconi, Francesco; Iyengar, Sunil; Schuh, Anna; Thornton, Patrick 分享 收藏
FGF7-FGFR2 autocrine signaling increases growth and chemoresistance of fusion-positive rhabdomyosarcomas Milton, Christopher I.; Selfe, Joanna; Aladowicz, Ewa; Man, Stella Y. K.; Bernauer, Carolina; Missiaglia, Edoardo; Walters, Zoe S.; Gatz, Susanne A.; Kelsey, Anna; Generali, Melanie; Box, Gary; Valenti, Melanie; de Haven-Brandon, Alexis; Galiwango, David; Hayes, Angela; Clarke, Matthew; Izquierdo, Elisa; Gonzalez De Castro, David; Raynaud, Florence I.; Kirkin, Vladimir; Shipley, Janet M. 分享 收藏
The impact ofSAMHD1expression and mutation status in mantle cell lymphoma: An analysis of theMCLYounger and Elderly trial Roider, Tobias; Wang, Xi; Huettl, Katrin; Mueller-Tidow, Carsten; Klapper, Wolfram; Rosenwald, Andreas; Stewart, James Peter; de Castro, David Gonzalez; Dreger, Peter; Hermine, Olivier; Kluin-Nelemans, Hanneke C.; Grabe, Niels; Dreyling, Martin; Pott, Christiane; Ott, German; Hoster, Eva; Dietrich, Sascha 分享 收藏
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Genomic landscape of platinum resistant and sensitive testicular cancers 铂类耐药和敏感睾丸癌的基因组景观 Loveday, Chey; Litchfield, Kevin; Proszek, Paula Z.; Cornish, Alex J.; Santo, Flavia; Levy, Max; Macintyre, Geoff; Holryod, Amy; Broderick, Peter; Dudakia, Darshna; Benton, Barbara; Al Bakir, Maise; Hiley, Crispin; Grist, Emily; Swanton, Charles; Huddart, Robert; Powles, Tom; Chowdhury, Simon; Shipley, Janet; O'Connor, Simon; Brenton, James D.; Reid, Alison; de Castro, David Gonzalez; Houlston, Richard S.; Turnbull, Clare 分享 收藏
NUQA: Estimating Cancer Spatial and Temporal Heterogeneity and Evolution through Alignment-Free Methods Roddy, Aideen C.; Jurek-Loughrey, Anna; Souza, Jose; Gilmore, Alan; O'Reilly, Paul G.; Stupnikov, Alexey; de Castro, David Gonzalez; Prise, Kevin M.; Salto-Tellez, Manuel; McArt, Darragh G. 分享 收藏
Analysis of KRAS, NRAS, BRAF, PIK3CA and TP53 mutations in a large prospective series of locally advanced rectal cancer patients Sclafani, Francesco; Wilson, Sanna Hulkki; Cunningham, David; De Castro, David Gonzalez; Kalaitzaki, Eleftheria; Begum, Ruwaida; Wotherspoon, Andrew; Capdevila, Jaume; Glimelius, Bengt; Rosello, Susana; Thomas, Janet; Tait, Daina; Brown, Gina; Oates, Jacqui; Chau, Ian 分享 收藏
Investigating the potential clinical benefit of Selumetinib in resensitising advanced iodine refractory differentiated thyroid cancer to radioiodine therapy (SEL-I-METRY): protocol for a multicentre UK single arm phase II trial Brown, Sarah R.; Hall, Andrew; Buckley, Hannah L.; Flanagan, Louise; de Castro, David Gonzalez; Farnell, Kate; Moss, Laura; Gregory, Rebecca; Newbold, Kate; Du, Yong; Flux, Glenn; Wadsley, Jonathan 分享 收藏
Ultra-Sensitive Mutation Detection and Genome-Wide DNA Copy Number Reconstruction by Error-Corrected Circulating Tumor DNA Sequencing Mansukhani, Sonia; Barber, Louise J.; Kleftogiannis, Dimitrios; Moorcraft, Sing Yu; Davidson, Michael; Woolston, Andrew; Proszek, Paula Zuzanna; Griffiths, Beatrice; Fenwick, Kerry; Herman, Bram; Matthews, Nik; O'Leary, Ben; Hulkki, Sanna; De Castro, David Gonzalez; Patel, Anisha; Wotherspoon, Andrew; Okachi, Aleruchi; Rana, Isma; Begum, Ruwaida; Davies, Matthew N.; Powles, Thomas; von Loga, Katharina; Hubank, Michael; Turner, Nick; Watkins, David; Chau, Ian; Cunningham, David; Lise, Stefano; Starling, Naureen; Gerlinger, Marco 分享 收藏
Detection of EGFR Variants in Plasma A Multilaboratory Comparison of a Real-Time PCR EGFR Mutation Test in Europe Keppens, Cleo; Palma, John F.; Das, Partha M.; Scudder, Sidney; Wen, Wei; Normanno, Nicola; van Krieken, J. Han; Sacco, Alessandra; Fenizia, Francesca; de Castro, David Gonzalez; Hoenigschnabl, Selma; Kern, Izidor; Lopez-Rios, Fernando; Lozano, Maria D.; Marchetti, Antonio; Halfon, Philippe; Schuuring, Ed; Setinek, Ulrike; Sorensen, Boe; Taniere, Phillipe; Tiemann, Markus; Vosmikova, Hana; Dequeker, Elisabeth M. C. 分享 收藏
Treatment and Survival Outcome of BRAF-Mutated Metastatic Colorectal Cancer: A Retrospective Matched Case-Control Study Kayhanian, Hamzeh; Goode, Emily; Sclafani, Francesco; Ang, Joo Ern; Gerlinger, Marco; de Castro, David Gonzalez; Shepherd, Scott; Peckitt, Clare; Rao, Sheela; Watkins, David; Chau, Ian; Cunningham, David; Starling, Naureen 分享 收藏
KRAS and BRAF mutations in circulating tumour DNA from locally advanced rectal cancer 局部晚期直肠癌循环肿瘤DNA的KRAS和BRAF突变 Sclafani, Francesco; Chau, Ian; Cunningham, David; Hahne, Jens C.; Vlachogiannis, George; Eltahir, Zakaria; Lampis, Andrea; Braconi, Chiara; Kalaitzaki, Eleftheria; De Castro, David Gonzalez; Wotherspoon, Andrew; Capdevila, Jaume; Glimelius, Bengt; Tarazona, Noelia; Begum, Ruwaida; Lote, Hazel; Wilson, Sanna Hulkki; Mentrasti, Giulia; Brown, Gina; Tait, Diana; Oates, Jacqueline; Valeri, Nicola 分享 收藏
Investigating the feasibility of tumour molecular profiling in gastrointestinal malignancies in routine clinical practice Moorcraft, S. Y.; de Castro, D. Gonzalez; Cunningham, D.; Jones, T.; Walker, B. A.; Peckitt, C.; Yuan, L. C.; Frampton, M.; Begum, R.; Eltahir, Z.; Wotherspoon, A.; Mendes, L. S. Teixeira; Wilson, S. Hulkki; Gillbanks, A.; Baratelli, C.; Fotiadis, N.; Patel, A.; Braconi, C.; Valeri, N.; Gerlinger, M.; Rao, S.; Watkins, D.; Chau, I.; Starling, N. 分享 收藏
Somatic cancer genetics in the UK: real-world data from phase I of the Cancer Research UK Stratified Medicine Programme Lindsay, Colin R.; Shaw, Emily C.; Blackhall, Fiona; Blyth, Kevin G.; Brenton, James D.; Chaturvedi, Anshuman; Clarke, Noel; Dick, Craig; Evans, Thomas R. J.; Hall, Geoff; Hanby, Andrew M.; Harrison, David J.; Johnston, Stephen R. D.; Mason, Malcolm D.; Morton, Dion; Newton-Bishop, Julia; Nicholson, Andrew G.; Oien, Karin A.; Popat, Sanjay; Rassl, Doris; Sharpe, Rowena; Taniere, Phillipe; Walker, Ian; Wallace, William A.; West, Nicholas P.; Butler, Rachel; de Castro, David Gonzalez; Griffiths, Mike; Johnson, Peter W. M. 分享 收藏
An evaluation of the challenges to developing tumor BRCA1 and BRCA2 testing methodologies for clinical practice Ellison, Gillian; Ahdesmaki, Miika; Luke, Sally; Waring, Paul M.; Wallace, Andrew; Wright, Ronnie; Rothlisberger, Benno; Ludin, Katja; Merkelbach-Bruse, Sabine; Heydt, Carina; Ligtenberg, Marjolijn J. L.; Mensenkamp, Arjen R.; de Castro, David Gonzalez; Jones, Thomas; Vivancos, Ana; Kondrashova, Olga; Pauwels, Patrick; Weyn, Christine; Hahnen, Eric; Hauke, Jan; Soong, Richie; Lai, Zhongwu; Dougherty, Brian; Carr, T. Hedley; Johnson, Justin; Mills, John; Barrett, J. Carl 分享 收藏