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Pulmonary dynamic hyperinflation augments pulmonary capillary wedge pressure during exercise in patients with heart failure with preserved ejection fraction 肺动态过度充气在运动期间加重心力衰竭伴射血分数保留患者的肺毛细血管楔压。 Leahy, Michael; MacNamara, James; Brazile, Tiffany; Wakeham, Denis; Samels, Mitchel; Hearon, Christopher; Tomlinson, Andrew; Balmain, Bryce; Babb, Tony; Levine, Benjamin; Sarma, Satyam 分享 收藏
The Effect of Anemia on the Mechanisms of Exercise Intolerance in Adults with HFpEF 贫血对成人HFpEF运动不耐受机制的影响 Manferdelli, Giorgio; Wakeham, Denis; Leahy, Michael; Skow, Rachel; Kissel, Claire; Brazile, Tiffany; MacNamara, James; Fadel, Paul; Haykowsky, Mark; Levine, Benjamin; Sarma, Satyam; Hearon, Christopher 分享 收藏
Blood Volume Prediction Equations Do Not Precisely Estimate Blood Volume in Adults with Heart Failure with Preserved Ejection Fraction (HFpEF) 血容量预测方程不能精确估计射血分数保留的心力衰竭（HFpEF）成年患者的血容量 Sooda, Meera; Wakeham, Denis; Samels, Mitchel; Brazile, Tiffany; Leahy, Michael; Manferdelli, Giorgio; Macnamara, James; Sarma, Satyam; Hearon, Christopher; Levine, Benjamin 分享 收藏
Oxygen uptake kinetics are not a specific marker of peripheral limitations to exercise among adults with heart failure with preserved ejection fraction 氧摄取动力学并非心力衰竭伴射血分数保留的成人中运动外周限制的特异性标志物。 Zuazua, Michael; Leahy, Michael; Campain, Joseph; Wakeham, Denis; Brazile, Tiffany; Samels, Mitchel; Macnamara, James; Sarma, Satyam; Hearon, Christopher; Levine, Benjamin 分享 收藏
Technical development and validation of a clinically applicable microenvironment classifier as a biomarker of tumour hypoxia for soft tissue sarcoma Forker, Laura J.; Bibby, Becky; Yang, Lingjian; Lane, Brian; Irlam, Joely; Mistry, Hitesh; Khan, Mairah; Valentine, Helen; Wylie, James; Shenjere, Patrick; Leahy, Michael; Gaunt, Piers; Billingham, Lucinda; Seddon, Beatrice M.; Grimer, Rob; Robinson, Martin; Choudhury, Ananya; West, Catharine 分享 收藏
Long-term efficacy update of crizotinib in patients with advanced, inoperable inflammatory myofibroblastic tumour from EORTC trial 90101 CREATE Schoffski, Patrick; Kubickova, Michaela; Wozniak, Agnieszka; Blay, Jean-Yves; Strauss, Sandra J.; Stacchiotti, Silvia; Switaj, Tomasz; Bucklein, Veit; Leahy, Michael G.; Italiano, Antoine; Isambert, Nicolas; Debiec-Rychter, Maria; Sciot, Raf; Lee, Che-Jui; Speetjens, Frank M.; Nzokirantevye, Axelle; Neven, Anouk; Kasper, Bernd 分享 收藏
Imatinib in combination with phosphoinositol kinase inhibitor buparlisib in patients with gastrointestinal stromal tumour who failed prior therapy with imatinib and sunitinib: a Phase 1b, multicentre study Gelderblom, Hans; Jones, Robin L.; George, Suzanne; Morales, Claudia Valverde; Benson, Charlotte; Blay, Jean-Yves; Renouf, Daniel J.; Doi, Toshihiko; Le Cesne, Axel; Leahy, Michael; Hertle, Sabine; Aimone, Paola; Brandt, Ulrike; Schoffski, Patrick 分享 收藏
Prospective precision medicine trial of crizotinib (C) in patients (pts) with advanced, inoperable inflammatory myofibroblastic tumor (IMFT) with and without ALK alterations: EORTC phase II study 90101 CREATE Schoffski, Patrick; Sufliarsky, Jozef; Gelderblom, Hans; Blay, Jean-Yves; Strauss, Sandra J.; Stacchiotti, Silvia; Rutkowski, Piotr; Lindner, Lars H.; Leahy, Michael G.; Italiano, Antoine; Isambert, Nicolas; Debiec-Rychter, Maria; Sciot, Raf; Van Cann, Thomas; Marreaud, Sandrine; Nzokirantevye, Axelle; Collette, Sandra; Wozniak, Agnieszka 分享 收藏
Crizotinib in patients with advanced, inoperable inflammatory myofibroblastic tumours with and without anaplastic lymphoma kinase gene alterations (European Organisation for Research and Treatment of Cancer 90101 CREATE): a multicentre, single-drug, prospective, non-randomised phase 2 trial Schoffski, Patrick; Sufliarsky, Jozef; Gelderblom, Hans; Blay, Jean-Yves; Strauss, Sandra J.; Stacchiotti, Silvia; Rutkowski, Piotr; Lindner, Lars H.; Leahy, Michael G.; Italiano, Antoine; Isambert, Nicolas; Debiec-Rychter, Maria; Sciot, Raf; Van Cann, Thomas; Marreaud, Sandrine; Nzokirantevye, Axelle; Collette, Sandra; Wozniak, Agnieszka 分享 收藏
The tyrosine kinase inhibitor crizotinib does not have clinically meaningful activity in heavily pre-treated patients with advanced alveolar rhabdomyosarcoma with FOXO rearrangement: European Organisation for Research and Treatment of Cancer phase 2 trial 90101 'CREATE' Schoffski, Patrick; Wozniak, Agnieszka; Leahy, Michael G.; Aamdal, Steinar; Rutkowski, Piotr; Bauer, Sebastian; Richter, Stephan; Gruenwald, Viktor; Debiec-Rychter, Maria; Sciot, Raf; Geoerger, Birgit; Marreaud, Sandrine; Collette, Sandra; Nzokirantevye, Axelle; Strauss, Sandra J. 分享 收藏
Activity and safety of crizotinib in patients with alveolar soft part sarcoma with rearrangement of TFE3: European Organization for Research and Treatment of Cancer (EORTC) phase II trial 90101 'CREATE' Schoffski, P.; Wozniak, A.; Kasper, B.; Aamdal, S.; Leahy, M. G.; Rutkowski, P.; Bauer, S.; Gelderblom, H.; Italiano, A.; Lindner, L. H.; Hennig, I.; Strauss, S.; Zakotnik, B.; Anthoney, A.; Albiges, L.; Blay, J. -Y.; Reichardt, P.; Sufliarsky, J.; van der Graaf, W. T. A.; Debiec-Rychter, M.; Sciot, R.; Van Cann, T.; Marreaud, S.; Raveloarivahy, T.; Collette, S.; Stacchiotti, S. 分享 收藏
Activity and safety of crizotinib in patients with advanced clear-cell sarcoma with MET alterations: European Organization for Research and Treatment of Cancer phase II trial 90101 'CREATE' Schoffski, P.; Wozniak, A.; Stacchiotti, S.; Rutkowski, P.; Blay, J. -Y.; Lindner, L. H.; Strauss, S. J.; Anthoney, A.; Duffaud, F.; Richter, S.; Gruenwald, V.; Leahy, M. G.; Reichardt, P.; Sufliarsky, J.; van der Graaf, W. T.; Sciot, R.; Debiec-Rychter, M.; van Cann, T.; Marreaud, S.; Lia, M.; Raveloarivahy, T.; Collette, L.; Bauer, S. 分享 收藏
Doxorubicin-based adjuvant chemotherapy in soft tissue sarcoma: pooled analysis of two STBSG-EORTC phase III clinical trials Le Cesne, A.; Ouali, M.; Leahy, M. G.; Santoro, A.; Hoekstra, H. J.; Hohenberger, P.; Van Coevorden, F.; Rutkowski, P.; Van Hoesel, R.; Verweij, J.; Bonvalot, S.; Steward, W. P.; Gronchi, A.; Hogendoorn, P. C. W.; Litiere, S.; Marreaud, S.; Blay, J. Y.; Van der Graaf, W. T. A. 分享 收藏
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Randomised phase III trial of trabectedin versus doxorubicin-based chemotherapy as first-line therapy in translocation-related sarcomas 在易位相关的肉瘤中，基于trabe的化疗与基于阿霉素的化疗作为一线治疗的随机III期试验 Blay, Jean-Yves; Leahy, Michael G.; Binh Bui Nguyen; Patel, Shreyaskumar R.; Hohenberger, Peter; Santoro, Armando; Staddon, Arthur P.; Penel, Nicolas; Piperno-Neumann, Sophie; Hendifar, Andrew; Lardelli, Pilar; Nieto, Antonio; Alfaro, Vicente; Chawla, Sant P. 分享 收藏
Brostallicin versus doxorubicin as first-line chemotherapy in patients with advanced or metastatic soft tissue sarcoma: An European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group randomised phase II and pharmacogenetic study Gelderblom, H.; Blay, J. Y.; Seddon, B. M.; Leahy, M.; Ray-Coquard, I.; Sleijfer, S.; Kerst, J. M.; Rutkowski, P.; Bauer, S.; Ouali, M.; Marreaud, S.; van der Straaten, R. J. H. M.; Guchelaar, H-J; Weitman, S. D.; Hogendoorn, P. C. W.; Hohenberger, P. 分享 收藏
Rationale and design of a UK database for a rare cancer type: the GEM Registry for gastrointestinal stromal tumours Bulusu, V. R.; Fullarton, J.; Leahy, M.; Morgan, C.; Rasheed, A.; Taniere, P.; Toh, S.; Verrill, M.; White, J.; Judson, I. 分享 收藏
Detection of oncogenic kinase mutations in circulating plasma DNA and correlation with clinical benefit in the phase III GRID study of regorafenib vs placebo in TKI-refractory metastatic GIST. Demetri, George D.; Jeffers, Michael; Reichardt, Peter; Kang, Yoon-Koo; Blay, Jean-Yves; Rutkowski, Piotr; Gelderblom, Hans; Hohenberger, Peter; Leahy, Michael; von Mehren, Margaret; Joensuu, Heikki; Badalamenti, Giuseppe; Blackstein, Martin; Le Cesne, Axel; Schoffski, Patrick; Maki, Robert G.; Bauer, Sebastian; Binh Bui Nguyen; Xu, Jianming; Nishida, Toshirou; Chung, John; Lathia, Chetan D.; Kappeler, Christian; Kuss, Iris; Laurent, Dirk; Casali, Paolo G. 分享 收藏
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