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A

Alfred S.L. Cheng

the chinese university of hong kong

64H指数
474论文数
1.3W被引数
收录论文 150
发表时间
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4D nucleome landscape reveals dissolution of bipartite active X chromosome in liver cancer development四维核体景观揭示双组分活跃X染色体在肝癌发展中的溶解
errNature Cell Biology
IF19.1
err2026-09-11
err0
PREAI
errXiaoli Xie; Delin Tan; Jingyun Mo; Yang Xu; Qingqiang Ni; Ting Liu; Huaiming Wang; Bingjie Chen; Yujia Liao; Yingnan Lin; Wanting Chen; Susu Luo; Qing Fang; Menglan Zhao; Yangyinhui Yu; Cunjing Zheng; Ruolin Cui; Jiaying Wang; Hong Chang; Qing Gong; Alfred Sze-Lok Cheng; Huiqing Jiang; Tingting Li; Jia Wang
err分享
err收藏
Wild-type KRAS activation drives evasion of interferon-mediated immunity and resistance to immunotherapy in hepatocellular carcinoma野生型KRAS的激活驱动干扰素介导免疫的逃避以及对免疫治疗的耐药性在肝细胞癌中。
errNature Communications
IF15.7
err2025-11-11
err0
errOAAI
errMartina Mang Leng Lei; Carmen Oi Ning Leung; Rainbow Wing Hei Leung; Xue Qian Wu; Katherine Po Sin Chung; Catherine Yu Jia Gu; Mandy Sze Man Chan; Wing Ki Chau; Quan Hua Mu; Kai Yu Ng; Man Tong; Jing Ping Yun; Jia Ming Nickolas Teo; Guang Sheng Ling; Patrick Pak Chun Wong; Stephen Lam Chan; Zhe Wen Xiong; Alfred Sze Lok Cheng; Jin Ding; Stephanie Ma; Terence Kin Wah Lee
err分享
err收藏
Towards biomarker-driven cancer immunotherapy: the rising of a protein phosphatase regulator迈向生物标志物驱动的癌症免疫治疗：一种蛋白磷酸酶调节因子的崛起
errSignal Transduction and Targeted Therapy
IF52.7
err2025-10-14
err0
errOAAI
errXiaoyu Liu; Weiqin Yang; Alfred Sze-Lok Cheng
err分享
err收藏
Correction: PPARγ is essential for protection against nonalcoholic steatohepatitis更正：PPARγ对于预防非酒精性脂肪性肝炎至关重要。
errGene Therapy
IF4.5
err2025-09-26
err0
PREAI
errC. W. Wu; E. S. H. Chu; C. N. Y. Lam; A. S. L. Cheng; C. W. Lee; V. W. S. Wong; J. J. Y. Sung; J. Yu
err分享
err收藏
Epigenetic therapeutics to overcome resistance against immune checkpoint inhibitors (ICI) in hepatocellular carcinoma (HCC): a proof-of-concept clinical trial表观遗传疗法以克服肝细胞癌(HCC)中针对免疫检查点抑制剂(ICI)的耐药性：一项概念验证临床试验
errLANCET REGIONAL HEALTH-WESTERN PACIFIC
IF8.1
err2025-02-01
err0
errOAAI
errChan, Stephen; Cheng, Alfred; La Thangue, Nick; Kerr, David
err分享
err收藏
Germline Human Leukocyte Antigen Status is Associated With Immunotherapy-Induced Pneumonitis and Treatment Response in Patients With Non-Small Cell Lung Cancer With High Programmed Death-Ligand 1 Expression
errJTO CLINICAL AND RESEARCH REPORTS
IF3.5
err2025-01-01
err0
errOAAI
errCheung, Alvin H. K.; Mui, Zeta; Yeung, Walter W.; Chow, Chit; Yu, Mandy F.; Chen, Olivia H.; Wong, Kit-Yee; Xie, Fuda; Lau, Yat Ming; Cheng, Alfred S. -L.; Kang, Wei; To, Ka-Fai; Mok, Tony S.; Li, Molly S. C.
err分享
err收藏
PPP1R15A-expressing monocytic MDSCs promote immunosuppressive liver microenvironment in fibrosisassociated hepatocellular carcinoma
errJHEP REPORTS
IF7.5
err2024-07-01
err0
errOAAI
errLiu, Xiaoyu; Liu, Man; Wu, Haoran; Tang, Wenshu; Yang, Weiqin; Chan, Thomas T. H.; Zhang, Lingyun; Chen, Shufen; Xiong, Zhewen; Liang, Jianxin; Si-Tou, Willis Wai-Yiu; Shu, Ting; Li, Jingqing; Cao, Jianquan; Zhong, Chengpeng; Sun, Hanyong; Kwong, Tsz Tung; Leung, Howard H. W.; Wong, John; Lai, Paul Bo-San; To, Ka-Fai; Xiang, Tingxiu; Sung, Joseph Jao-Yiu; Chan, Stephen Lam; Zhou, Jingying; Cheng, Alfred Sze-Lok
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err收藏
Integrative analysis reveals associations between oral microbiota dysbiosis and host genetic and epigenetic aberrations in oral cavity squamous cell carcinoma
errNPJ BIOFILMS AND MICROBIOMES
IF9.2
err2024-04-08
err11
errOAAI
errCai, Liuyang; Zhu, Hengyan; Mou, Qianqian; Wong, Po Yee; Lan, Linlin; Ng, Cherrie W. K.; Lei, Pu; Cheung, Man Kit; Wang, Daijuanru; Wong, Eddy W. Y.; Lau, Eric H. L.; Yeung, Zenon W. C.; Lai, Ronald; Meehan, Katie; Fung, Sherwood; Chan, Kwan Chee A.; Lui, Vivian W. Y.; Cheng, Alfred S. L.; Yu, Jun; Chan, Paul K. S.; Chan, Jason Y. K.; Chen, Zigui
err分享
err收藏
Targeted Protein O-GlcNAcylation Using Bifunctional Small Molecules使用双功能小分子靶向蛋白o-glcnac化
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-04-01
err6
errOAAI
errMa, Bowen; Khan, Khadija Shahed; Xu, Tongyang; Amada, Josefina Xeque; Guo, Zhihao; Huang, Yunpeng; Yan, Yu; Lam, Henry; Cheng, Alfred Sze-Lok; Ng, Billy Wai-Lung
err分享
err收藏
Deciphering the cellular and molecular determinants of immunotherapy resistance in NASH-associated hepatocellular carcinoma by single-cell analysis
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errZhang, Lingyun; Zhang, Yiling; Tang, Wenshu; Xiong, Zhewen; Liu, Xiaoyu; Liang, Zhixian; Tsang, Yuk Wah; Yang, Weiqin; Long, Xiaohang; Cheng, Alfred Sze Lok
err分享
err收藏
HDAC9 as a potential regulator of lenvatinib resistance in hepatocellular carcinoma
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errXie, Yunong; Zhang, Minghe; Liu, Yan; Liu, Linglin; Cheng, Alfred Sze-Lok; Ma, Stephanie; Tong, Man
err分享
err收藏
Accurate identification of structural variations from cancer samples
errBRIEFINGS IN BIOINFORMATICS
IF7.7
err2024-01-16
err1
errOAAI
errLi, Le; Hong, Chenyang; Xu, Jie; Chung, Claire Yik-Lok; Leung, Alden King-Yung; Boncan, Delbert Almerick T.; Cheng, Lixin; Lo, Kwok-Wai; Lai, Paul B. S.; Wong, John; Zhou, Jingying; Cheng, Alfred Sze-Lok; Chan, Ting-Fung; Yue, Feng; Yip, Kevin Y.
err分享
err收藏
The molecular classification of cancer-associated fibroblasts on a pan-cancer single-cell transcriptional atlas泛癌症单细胞转录图谱上癌症相关成纤维细胞的分子分类
errCLINICAL AND TRANSLATIONAL MEDICINE
IF6.8
err2023-12-26
err11
errOAAI
errChen, Bonan; Chan, Wai Nok; Xie, Fuda; Mui, Chun Wai; Liu, Xiaoli; Cheung, Alvin H. K.; Lung, Raymond W. M.; Chow, Chit; Zhang, Zhenhua; Fang, Canbin; Yu, Peiyao; Shi, Shihua; Zhou, Shikun; Chen, Guoming; Wang, Zhangding; Wang, Shouyu; Ding, Xiaofan; Huang, Bing; Liang, Li; Dong, Yujuan; Wong, Chi Chun; Wu, William K. K.; Cheng, Alfred S. L.; Wong, Nathalie; Yu, Jun; Lo, Kwok Wai; Tse, Gary M. K.; Kang, Wei; To, Ka Fai
err分享
err收藏
The E2F1-HOXB9/PBX2-CDK6 axis drives gastric tumorigenesis and serves as a therapeutic target in gastric cancer
errJOURNAL OF PATHOLOGY
IF5.2
err2023-06-05
err5
errOAAI
errZhang, Jinglin; Chen, Bonan; Wang, Yifei; Liu, Xiaoli; Yan, Huan; Wong, Kit Yee; Chan, Aden K. Y.; Cheung, Alvin H. K.; Chow, Chit; Xu, Dazhi; Wang, Shouyu; Huang, Bing; Liang, Li; Ke, Huixing; Wong, Chi Chun; Wu, William K. K.; Cheng, Alfred S. L.; Yu, Jun; Lo, Kwok Wai; To, Ka Fai; Kang, Wei
err分享
err收藏
Neuropathological signatures revealed by transcriptomic and proteomic analysis in Pten-deficient mouse models
errSCIENTIFIC REPORTS
IF3.9
err2023-04-25
err1
errOAAI
errCheung, Stanley K. K.; Kwok, Jacinda; Or, Penelope M. Y.; Wong, Chi Wai; Feng, Bo; Choy, Kwong Wai; Chang, Raymond C. C.; Burbach, J. Peter H.; Cheng, Alfred S. L.; Chan, Andrew M.
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err收藏
Targeting SMARCAL1 as a therapeutic strategy to enhance cGAS/STING signaling in gastric cancer
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errHsu, Po-Yen; Chuang, Yu-Ming; Lin, Shu-Hui; Lee, Yu-Ting; Chen, Yin-Chen; Ng, Enders K. W.; Yeh, Kun-Tu; Cheng, Alfred S. L.; Chan, Michael W. Y.
err分享
err收藏
Compromised browning in white adipose tissue of ageing people
errEUROPEAN JOURNAL OF ENDOCRINOLOGY
IF5.2
err2023-02-08
err1
PREAI
errGu, Ping; Ding, Kai; Lu, Lei; Zhang, Yu; Wang, Wei; Guo, Qingyu; Liao, Yannian; Yang, Bingjie; Wang, Tiantian; Zhou, Changsheng; Lu, Bin; Kong, Alice P. S.; Cheng, Alfred S.; Hui, Hannah Xiaoyan; Shao, Jiaqing
err分享
err收藏
Cold-Induced Reprogramming of Subcutaneous White Adipose Tissue Assessed by Single-Cell and Single-Nucleus RNA Sequencing
errRESEARCH
IF10.7
err2023-01-01
err16
errOAAI
errLiu, Qing; Long, Qiaoyun; Zhao, Jiayu; Wu, Wenjie; Lin, Zexin; Sun, Wei; Gu, Ping; Deng, Tuo; Loomes, Kerry Martin; Wu, Donghai; Kong, Alice P. S.; Zhou, Jingying; Cheng, Alfred S.; Hui, Hannah Xiaoyan
err分享
err收藏
Fibrotic immune microenvironment remodeling mediates superior anti-tumor efficacy of a nano-PD-L1 trap in hepatocellular carcinoma
errMOLECULAR THERAPY
IF12
err2023-01-01
err16
errOAAI
errLiu, Xiaoyu; Zhou, Jingying; Wu, Haoran; Chen, Shufen; Zhang, Lingyun; Tang, Wenshu; Duan, Liang; Wang, Ying; McCabe, Eleanor; Hu, Mengying; Yu, Zhuo; Liu, Hanzhuang; Choi, Chung Hang Jonathan; Sung, Joseph Jao-yiu; Huang, Leaf; Liu, Rihe; Cheng, Alfred Sze-lok
err分享
err收藏
Cancer-associated fibroblasts potentiate colorectal cancer progression by crosstalk of the IGF2-IGF1R and Hippo-YAP1 signaling pathways
errJOURNAL OF PATHOLOGY
IF5.2
err2022-12-17
err27
PREAI
errZhang, Jinglin; Chen, Bonan; Li, Hui; Wang, Yifei; Liu, Xiaoli; Wong, Kit Yee; Chan, Wai Nok; Chan, Aden K. Y.; Cheung, Alvin H. k; Leung, Kam Tong; Dong, Yujuan; Pan, Yi; Ke, Huixing; Liang, Li; Zhou, Zhaocai; Xiao, Jianyong; Wong, Chi Chun; Wu, William K. K.; Cheng, Alfred S. L.; Ma, Brigette B. Y.; Yu, Jun; Lo, Kwok Wai; Kang, Wei; To, Ka Fai
err分享
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研究方向

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合作学者
合作期刊
J
Joseph J.�Y. Sung
H 指数: 171 · 论文数: 2.2K
R
Richard L. Gallo
H 指数: 148 · 论文数: 885
V
Vincent Wai‐Sun Wong
H 指数: 142 · 论文数: 1.2K
余君 封面图
余君 (Jun Yu)
H 指数: 133 · 论文数: 1.8K
J
Jean‐Pierre J. Issa
H 指数: 130 · 论文数: 985
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