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K

Kazuhiro Kakimi

Department of Immunology

49H指数
317论文数
7.4K被引数
收录论文 105
发表时间
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Spatial transcriptomics reveals cell state-level organization and chemokine network architecture within tertiary lymphoid structures空间转录组学揭示三级淋巴结构内细胞状态水平的组织结构和趋化因子网络架构
errCancer Immunology Immunotherapy
IF5.1
err2026-08-31
err0
errOAAI
errAnge Yan; Tomohiro Iwasawa; Nobuyuki Tanaka; Kazuhiro Kakimi; Artem Lysenko; Tatsuhiko Tsunoda
err分享
err收藏
Antiemesis Corticosteroids Potentiate Checkpoint Blockade Efficacy by Normalizing the Immune Microenvironment in Metastatic Murine Breast Cancer (Adv. Sci. 14/2026)抗呕吐皮质类固醇通过调节免疫微环境增强检查点阻断疗法在转移性小鼠乳腺癌中的疗效 (Adv. Sci. 14/2026)
errAdvanced Science
IF14.1
err2026-03-09
err0
errOAAI
errJohn D. Martin; Koji Nagaoka; Myrofora Panagi; Akihiro Hosoi; Fotios Mpkeris; Pengwen Chen; Thahomina T. Khan; Margaret R. Martin; Changbo Sun; Chrysovalantis Voutouri; Maria Louca; Panagiotis Papageorgis; Akira Sumiyoshi; Nobuhiro Nitta; Kazuyoshi Takeda; Ichio Aoki; Kazunori Kataoka; Triantafyllos Stylianopoulos; Kazuhiro Kakimi; Horacio Cabral
err分享
err收藏
NeoPAIR-T: Functional Mapping of Neoantigen–TCR Pairs Using a CRISPR-Engineered Jurkat Reporter SystemNeoPAIR-T: 利用CRISPR工程化Jurkat报告系统对新生抗原–TCR对进行功能映射
errCells
IF5.2
err2026-03-03
err0
errOAAI
errKoji Nagaoka; Yukari Kobayashi; Kazuhiro Kakimi
err分享
err收藏
Antiemesis Corticosteroids Potentiate Checkpoint Blockade Efficacy by Normalizing the Immune Microenvironment in Metastatic Murine Breast Cancer抗呕吐皮质类固醇通过归一化转移性小鼠乳腺癌的免疫微环境来增强检查点阻断的疗效
errAdvanced Science
IF14.1
err2025-11-28
err0
errOAAI
errJohn D. Martin; Koji Nagaoka; Myrofora Panagi; Akihiro Hosoi; Fotios Mpkeris; Pengwen Chen; Thahomina T. Khan; Margaret R. Martin; Changbo Sun; Chrysovalantis Voutouri; Maria Louca; Panagiotis Papageorgis; Akira Sumiyoshi; Nobuhiro Nitta; Kazuyoshi Takeda; Ichio Aoki; Kazunori Kataoka; Triantafyllos Stylianopoulos; Kazuhiro Kakimi; Horacio Cabral
err分享
err收藏
Combination of ionizable lipids with oleic acid and vitamin E scaffolds for RNA cancer vaccine delivery可电离脂质与油酸和维生素E骨架的组合用于RNA癌症疫苗递送
errJournal of Controlled Release
IF11.5
err2025-11-17
err0
PREAI
errJessica Anindita; Hiroki Tanaka; Ryotaro Oyama; Atsuya Matsumaru; Yuta Nakai; Kota Tange; Koji Nagaoka; Hideyuki Nakanishi; Takeshi Kawamura; Toshiya Tanaka; Takefumi Yamashita; Akihiro Kuroda; Sachiyo Nomura; Hiroto Hatakeyama; Keiji Itaka; Tatsuhiko Kodama; Kazuhiro Kakimi; Hidetaka Akita
err分享
err收藏
Neoantigen mRNA vaccines induce progenitor-exhausted T cells that support anti-PD-1 therapy in gastric cancer with peritoneal metastasis新抗原mRNA疫苗诱导祖细胞耗竭型T细胞，支持在伴有腹膜转移的胃癌中抗PD-1疗法
errGastric Cancer
IF5.1
err2025-07-31
err0
errOAAI
errKoji Nagaoka; Hideyuki Nakanishi; Hiroki Tanaka; Jessica Anindita; Takeshi Kawamura; Toshiya Tanaka; Takefumi Yamashita; Akihiro Kuroda; Sachiyo Nomura; Hidetaka Akita; Keiji Itaka; Tatsuhiko Kodama; Kazuhiro Kakimi
err分享
err收藏
Why combine and why neoadjuvant? Tumor immunological perspectives on chemoimmunotherapy in triple-negative breast cancer为何联合，为何新辅助？从肿瘤免疫学角度探讨三阴性乳腺癌的化免疫疗法
errBREAST CANCER
IF2.9
err2025-05-06
err0
errOAAI
errKakimi, Kazuhiro; Sugie, Tomoharu
err分享
err收藏
Tumor immunology and immunotherapy for endometrial cancer
errEXPERT OPINION ON INVESTIGATIONAL DRUGS
IF4.1
err2025-02-11
err0
errOAAI
errMurakami, Kosuke; Takamura, Shiki; Kakimi, Kazuhiro; Matsumura, Noriomi
err分享
err收藏
Optimal radiation dose to induce an abscopal effect by combining carbon-ion radiotherapy and anti-CTLA4 antibody
errNEOPLASIA
IF7.7
err2025-02-01
err1
errOAAI
errMa, Liqiu; Li, Yang; Sakamoto, Yoshimitsu; Xie, Lin; Suzuki, Saaya; Yoshida, Yukari; Sui, Li; Guo, Gang; Wen, Jialing; Ren, Wangcai; Kakimi, Kazuhiro; Osada, Kensuke; Takahashi, Akihisa; Shimokawa, Takashi
err分享
err收藏
Predicting chemotherapy responsiveness in gastric cancer through machine learning analysis of genome, immune, and neutrophil signatures通过基因组，免疫和中性粒细胞特征的机器学习分析预测胃癌的化疗反应性
errGASTRIC CANCER
IF5.1
err2024-12-02
err0
errOAAI
errSasagawa, Shota; Honma, Yoshitaka; Peng, Xinxin; Maejima, Kazuhiro; Nagaoka, Koji; Kobayashi, Yukari; Oosawa, Ayako; Johnson, Todd A.; Okawa, Yuki; Liang, Han; Kakimi, Kazuhiro; Yamada, Yasuhide; Nakagawa, Hidewaki
err分享
err收藏
Nanoenabled IL-15 Superagonist via Conditionally Stabilized Protein-Protein Interactions Eradicates Solid Tumors by Precise Immunomodulation通过条件稳定的蛋白质-蛋白质相互作用的纳米IL-15超级激动剂通过精确的免疫调节根除实体瘤
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-10-02
err0
PREAI
errChen, Pengwen; Li, Shangwei; Nagaoka, Koji; Kakimi, Kazuhiro; Kataoka, Kazunori; Cabral, Horacio
err分享
err收藏
Janus kinase inhibitor overcomes resistance to immune checkpoint inhibitor treatment in peritoneal dissemination of gastric cancer in C57BL/6 J mice
errGASTRIC CANCER
IF5.1
err2024-05-28
err2
errOAAI
errDu, Wan-Ying; Masuda, Hiroki; Nagaoka, Koji; Yasuda, Tomohiko; Kuge, Komei; Seto, Yasuyuki; Kakimi, Kazuhiro; Nomura, Sachiyo
err分享
err收藏
Glioblastoma with high O6-methyl-guanine DNA methyltransferase expression are more immunologically active than tumors with low MGMT expression具有高O6-methyl-guanine DNA甲基转移酶表达的胶质母细胞瘤比具有低MGMT表达的肿瘤具有更高的免疫活性
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-01-15
err2
errOAAI
errKushihara, Yoshihiro; Tanaka, Shota; Kobayashi, Yukari; Nagaoka, Koji; Kikuchi, Miyu; Nejo, Takahide; Yamazawa, Erika; Nambu, Shohei; Kugasawa, Kazuha; Takami, Hirokazu; Takayanagi, Shunsaku; Saito, Nobuhito; Kakimi, Kazuhiro
err分享
err收藏
Immuno-genomic analysis reveals eosinophilic feature and favorable prognosis of female non-smoking esophageal squamous cell carcinomas
errCANCER LETTERS
IF10.1
err2024-01-01
err3
errOAAI
errOkawa, Yuki; Sasagawa, Shota; Kato, Hiroaki; Johnson, Todd A.; Nagaoka, Koji; Kobayashi, Yukari; Hayashi, Akimasa; Shibayama, Takahiro; Maejima, Kazuhiro; Tanaka, Hiroko; Miyano, Satoru; Shibahara, Junji; Nishizuka, Satoshi; Hirano, Satoshi; Seto, Yasuyuki; Iwaya, Takeshi; Kakimi, Kazuhiro; Yasuda, Takushi; Nakagawa, Hidewaki
err分享
err收藏
Tumor steatosis and glutamine synthetase expression in patients with advanced hepatocellular carcinoma receiving atezolizumab plus bevacizumab therapy
errHEPATOLOGY RESEARCH
IF3.4
err2023-06-23
err4
PREAI
errKurebayashi, Yutaka; Tsujikawa, Hanako; Sugimoto, Katsutoshi; Yunaiyama, Daisuke; Araki, Yoichi; Saito, Kazuhiro; Takahashi, Hiroshi; Kakegawa, Tatsuya; Wada, Takuya; Tomita, Yusuke; Abe, Masakazu; Yoshimasu, Yu; Takeuchi, Hirohito; Hirata, Taiki; Sakamaki, Kentaro; Kakimi, Kazuhiro; Nagao, Toshitaka; Itoi, Takao; Sakamoto, Michiie
err分享
err收藏
Increased diversity with reduced diversity evenness of tumor infiltrating T-cells for the successful cancer immunotherapy (vol 8, 1058, 2018)
errSCIENTIFIC REPORTS
IF3.9
err2023-04-26
err2
errOAAI
errHosoi, Akihiro; Takeda, Kazuyoshi; Nagaoka, Koji; Iino, Tamaki; Matsushita, Hirokazu; Ueha, Satoshi; Aoki, Shin; Matsushima, Kouji; Kubo, Masato; Morikawa, Teppei; Kitaura, Kazutaka; Suzuki, Ryuji; Kakimi, Kazuhiro
err分享
err收藏
pH-sensitive polymeric micelles loading IL-12 profoundly inflame the tumor microenvironment to eradicate cold tumors
errCANCER RESEARCH
IF16.6
err2023-04-14
err0
PREAI
errCabral, Horacio; Chen, Pengwen; Nagaoka, Koji; Miyazaki, Takuya; Kataoka, Kazunori; Kakimi, Kazuhiro
err分享
err收藏
Single-Cell Phenotyping of CD73 Expression Reveals the Diversity of the Tumor Immune Microenvironment and Reflects the Prognosis of Bladder CancerCD73表达的单细胞表型揭示了肿瘤免疫微环境的多样性并反映了膀胱癌的预后
errLABORATORY INVESTIGATION
IF4.2
err2023-04-01
err3
PREAI
errIzawa, Mizuki; Tanaka, Nobuyuki; Murakami, Tetsushi; Anno, Tadatsugu; Teranishi, Yu; Takamatsu, Kimiharu; Mikami, Shuji; Kakimi, Kazuhiro; Imamura, Takeshi; Matsumoto, Kazuhiro; Oya, Mototsugu
err分享
err收藏
An IL-12-Based Nanocytokine Safely Potentiates Anticancer Immunity through Spatiotemporal Control of Inflammation to Eradicate Advanced Cold Tumors
errADVANCED SCIENCE
IF14.1
err2023-02-05
err16
errOAAI
errChen, Pengwen; Yang, Wenqian; Nagaoka, Koji; Huang, George Lo; Miyazaki, Takuya; Hong, Taehun; Li, Shangwei; Igarashi, Kazunori; Takeda, Kazuyoshi; Kakimi, Kazuhiro; Kataoka, Kazunori; Cabral, Horacio
err分享
err收藏
Immunotherapies targeting neoantigens are effective in PD-1 blockade-resistant tumors靶向新抗原的免疫疗法在PD-1阻断耐药肿瘤中有效
errINTERNATIONAL JOURNAL OF CANCER
IF4.7
err2022-12-13
err7
PREAI
errSun, Changbo; Nagaoka, Koji; Kobayashi, Yukari; Maejima, Kazuhiro; Nakagawa, Hidewaki; Nakajima, Jun; Kakimi, Kazuhiro
err分享
err收藏

研究方向

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合作学者
合作期刊
A
Alessandro Sette
H 指数: 174 · 论文数: 1.4K
K
Kazunori Kataoka
H 指数: 153 · 论文数: 1.1K
T
Tasuku Honjo
H 指数: 143 · 论文数: 737
M
Masatoshi Kudo
H 指数: 143 · 论文数: 2.8K
K
Kouji Matsushima
H 指数: 130 · 论文数: 787
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