Pulido, Ines; Ollosi, Stephen; Aparisi, Salvador; Becker, Jeffrey H.; Aliena-Valero, Alicia; Benet, Marta; Rodriguez, Maria L.; Lopez, Adrian; Tamayo-Torres, Eva; Chulia-Peris, Lourdes; Garcia-Canaveras, Juan Carlos; Soucheray, Margaret; Dalheim, Annika, V; Salom, Juan B.; Qiu, Wei; Kaja, Simon; Fernandez-Coronado, Javier Alcacer; Alandes, Sandra; Alcacer, Javier; Al-Shahrour, Fatima; Borgia, Jeffrey A.; Juan, Oscar; Nishimura, Michael, I; Lahoz, Agustin; Carretero, Julian; Shimamura, Takeshi

CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC

CANCER RESEARCH

IF16.6

2019-09-0347

OAAI

Becker, Jeffrey H.; Gao, Yandi; Soucheray, Margaret; Pulido, Ines; Kikuchi, Eiki; Rodriguez, Maria L.; Gandhi, Rutu; Lafuente-Sanchis, Aranzazu; Aupi, Miguel; Alcacer Fernandez-Coronado, Javier; Martin-Martorell, Paloma; Cremades, Antonio; Galbis-Caravajal, Jose M.; Alcacer, Javier; Christensen, Camilla L.; Simms, Patricia; Hess, Ashley; Asahina, Hajime; Kahle, Michael P.; Al-Shahrour, Fatima; Borgia, Jeffrey A.; Lahoz, Agustin; Insa, Amelia; Juan, Oscar; Janne, Pasi A.; Wong, Kwok-Kin; Carretero, Julian; Shimamura, Takeshi

Inhibition of mutant EGFR in NSCLC promotes endothelin-1-mediated NSCLC disease progression and angiogenesis

CANCER RESEARCH

IF16.6

2018-07-010

PRE

A new role for LKB1 to regulate Heat Shock Protein 90 activity

CANCER RESEARCH

IF16.6

2018-07-010

PRE

Metabolic vulnerabilities of mesenchymal-like EGFR-mutant NSCLC cells with acquired resistance to tyrosine kinase inhibitors

CANCER RESEARCH

IF16.6

2018-07-010

PRE

Suppression of Adaptive Responses to Targeted Cancer Therapy by Transcriptional Repression

CANCER DISCOVERY

IF33.3

2018-01-0794

OAAI

Rusan, Maria; Li, Kapsok; Li, Yvonne; Christensen, Camilla L.; Abraham, Brian J.; Kwiatkowski, Nicholas; Buczkowski, Kevin A.; Bockorny, Bruno; Chen, Ting; Li, Shuai; Rhee, Kevin; Zhang, Haikuo; Chen, Wankun; Terai, Hideki; Tavares, Tiffany; Leggett, Alan L.; Li, Tianxia; Wang, Yichen; Zhang, Tinghu; Kim, Tae-Jung; Hong, Sook-Hee; Poudel-Neupane, Neermala; Silkes, Michael; Mudianto, Tenny; Tan, Li; Shimamura, Takeshi; Meyerson, Matthew; Bass, Adam J.; Watanabe, Hideo; Gray, Nathanael S.; Young, Richard A.; Wong, Kwok-Kin; Hammerman, Peter S.

Suppression of adaptive responses to targeted therapies by transcriptional inhibition

CANCER RESEARCH

IF16.6

2017-07-010

PRE

TGFa upregulation mediates growth retardation in EGFR T790M mutant non-small cell lung cancer

CANCER RESEARCH

IF16.6

2016-07-150

PRE

Heterogeneity in Tumors and Resistance to EGFR TKI Therapy-Response

CANCER RESEARCH

IF16.6

2016-05-121

PREAI

STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment

STK11/LKB1缺乏促进中性粒细胞募集和促炎细胞因子产生，从而抑制肺肿瘤微环境中的T细胞活性

CANCER RESEARCH

IF16.6

2016-02-29482

Koyama, Shohei; Akbay, Esra A.; Li, Yvonne Y.; Aref, Amir R.; Skoulidis, Ferdinandos; Herter-Sprie, Grit S.; Buczkowski, Kevin A.; Liu, Yan; Awad, Mark M.; Denning, Warren L.; Diao, Lixia; Wang, Jing; Parra-Cuentas, Edwin R.; Wistuba, Ignacio I.; Soucheray, Margaret; Tran Thai; Asahina, Hajime; Kitajima, Shunsuke; Altabef, Abigail; Cavanaugh, Jillian D.; Rhee, Kevin; Gao, Peng; Zhang, Haikuo; Fecci, Peter E.; Shimamura, Takeshi; Hellmann, Matthew D.; Heymach, John V.; Hodi, F. Stephen; Freeman, Gordon J.; Barbie, David A.; Dranoff, Glenn; Hammerman, Peter S.; Wong, Kwok-Kin

Takeshi Shimamura

个人简介

教育背景

工作经历

荣誉奖项

研究方向