Jack W. Singer - Publications, H-index & Citations

Jack W. Singer

vanderbilt university

99H指数

603论文数

3.5W被引数

收录论文 36

发表时间

Assessing cardiac safety in oncology drug development

AMERICAN HEART JOURNAL

IF3.5

2019-08-01

OAAI

Seltzer, Jonathan H.; Gintant, Gary; Amiri-Kordestani, Laleh; Singer, Jack; Koplowitz, Luana Pesco; Moslehi, Javid J.; Barac, Ana; Yu, Anthony F.

Inhibition of interleukin-1 receptor-associated kinase-1 is a therapeutic strategy for acute myeloid leukemia subtypes

LEUKEMIA

IF13.4

2018-03-29

OAAI

Hosseini, Mona M.; Kurtz, Stephen E.; Abdelhamed, Sherif; Mahmood, Shawn; Davare, Monika A.; Kaempf, Andy; Elferich, Johannes; McDermott, Jason E.; Liu, Tao; Payne, Samuel H.; Shinde, Ujwal; Rodland, Karin D.; Mori, Motomi; Druker, Brian J.; Singer, Jack W.; Agarwal, Anupriya

Targeting JAK2 reduces GVHD and xenograft rejection through regulation of T cell differentiation 靶向JAK2通过调节T细胞分化减少GVHD和异种移植排斥反应

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-01-30

OAAI

Betts, Brian C.; Bastian, David; Iamsawat, Supinya; Hung Nguyen; Heinrichs, Jessica L.; Wu, Yongxia; Daenthanasanmak, Anusara; Veerapathran, Anandharaman; O'Mahony, Alison; Walton, Kelly; Reff, Jordan; Horna, Pedro; Sagatys, Elizabeth M.; Lee, Marie C.; Singer, Jack; Chang, Ying-Jun; Liu, Chen; Pidala, Joseph; Anasetti, Claudio; Yu, Xue-Zhong

Pacritinib versus best available therapy for the treatment of myelofibrosis irrespective of baseline cytopenias (PERSIST-1): an international, randomised, phase 3 trial

LANCET HAEMATOLOGY

IF17.7

2017-05-01

245

OAAI

Mesa, Ruben A.; Vannucchi, Alessandro M.; Mead, Adam; Egyed, Miklos; Szoke, Anita; Suvorov, Aleksandr; Jakucs, Janos; Perkins, Andrew; Prasad, Ritam; Mayer, Jiri; Demeter, Judit; Ganly, Peter; Singer, Jack W.; Zhou, Huafeng; Dean, James P.; te Boekhorst, Peter A.; Nangalia, Jyoti; Kiladjian, Jean-Jacques; Harrison, Claire N.

Phase 1/2 study of pacritinib, a next generation JAK2/FLT3 inhibitor, in myelofibrosis or other myeloid malignancies

JOURNAL OF HEMATOLOGY & ONCOLOGY

IF40.4

2016-12-08

OAAI

Verstovsek, Srdan; Odenike, Olatoyosi; Singer, Jack W.; Granston, Tanya; Al-Fayoumi, Suliman; Deeg, H. Joachim

Synergistic effect of pacritinib with erlotinib on JAK2-mediated resistance in epidermal growth factor receptor mutation-positive non-small cell lung cancer

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Ochi, Nobuaki; Isozaki, Hideko; Takeyama, Masami; Singer, Jack W.; Yamane, Hiromichi; Honda, Yoshihiro; Kiura, Katsuyuki; Takigawa, Nagio

Investigation of the absorption, metabolism, excretion, and mass balance of [14C]-pacritinib in healthy subjects: a phase I study

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Al-Fayoumi, Suliman; Amberg, Sherri; Zhou, Huafeng; Millard, Lindsey; Singer, Jack W.; Dean, James P.

Synergistic effect of pacritinib with erlotinib on JAK2-mediated resistance in epidermal gowth factor receptor mutation-positive non-small cell lung Cancer

EXPERIMENTAL CELL RESEARCH

IF3.5

2016-06-01

PREAI

Ochi, Nobuaki; Isozaki, Hideko; Takeyama, Masami; Singer, Jack W.; Yamane, Hiromichi; Honda, Yoshihiro; Kiura, Katsuyuki; Takigawa, Nagio

IVIG Infusions Deplete Donor-Specific HLA Antibodies in Lung Transplant Recipients

JOURNAL OF HEART AND LUNG TRANSPLANTATION

IF6

2016-04-01

OAAI

Kukreja, J.; Kopchaliiska, D.; Dincheva, G.; Bush, E.; Leard, L.; Brzezinski, M.; Hays, S.; Singer, J.; Rajalingam, R.

The Cost-effectiveness of Pixantrone for Third/Fourth-line Treatment of Aggressive Non-Hodgkin's Lymphoma

CLINICAL THERAPEUTICS

IF3.6

2016-03-01

OAAI

Muszbek, Noemi; Kadambi, Ananth; Lanitis, Tereza; Hatswell, Anthony J.; Patel, Dilip; Wang, Lixia; Singer, Jack W.; Pettengell, Ruth

Tolerability and toxicological profile of pixantrone (Pixuvri®) in juvenile mice. Comparative study with doxorubicin

REPRODUCTIVE TOXICOLOGY

IF2.8

2014-07-01

PREAI

Longo, Monica; Della Torre, Paola; Allievi, Cecilia; Morisetti, Alberto; Al-Fayoumi, Suliman; Singer, Jack W.

Evolution of the Association Between Obesity and Survival after Adult Lung Transplantation in the Lung Allocation Score Era

JOURNAL OF HEART AND LUNG TRANSPLANTATION

IF6

2014-04-01

OAAI

Snyder, M. E.; Peterson, E. R.; Singer, J.; Shah, R.; Golden, J.; Shin, J.; Wickersham, N.; Kawut, S. M.; Desai, A.; Katz, P.; Hays, S.; Kukreja, J.; Sonett, J. R.; Arcasoy, S. M.; D'Ovidio, F.; Ware, L. B.; Christie, J. D.; Lederer, D. J.

Comparison of pixantrone-based regimen (CPOP-R) with doxorubicin-based therapy (CHOP-R) for treatment of diffuse large B-cell lymphoma 基于pixantrone的方案 (cpop-r) 与基于阿霉素的疗法 (chop-r) 治疗弥漫性大b细胞淋巴瘤的比较

ANNALS OF ONCOLOGY

IF65.4

2013-10-01

OAAI

Herbrecht, R.; Cernohous, P.; Engert, A.; Le Gouill, S.; Macdonald, D.; Machida, C.; Myint, H.; Saleh, A.; Singer, J.; Wilhelm, M.; van der Jagt, R.

The Novel Anthracenedione, Pixantrone, Lacks Redox Activity and Inhibits Doxorubicinol Formation in Human Myocardium: Insight to Explain the Cardiac Safety of Pixantrone in Doxorubicin-Treated Patients

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2013-02-01

PREAI

Salvatorelli, Emanuela; Menna, Pierantonio; Paz, Odalys Gonzalez; Chello, Massimo; Covino, Elvio; Singer, Jack W.; Minotti, Giorgio

Pixantrone Dimaleate in Combination With Fludarabine, Dexamethasone, and Rituximab in Patients With Relapsed or Refractory Indolent Non-Hodgkin Lymphoma

CANCER

IF5.1

2011-06-16

OAAI

Srokowski, Tomasz P.; Liebmann, James E.; Modiano, Manuel R.; Cohen, Gary I.; Pro, Barbara; Romaguera, Jorge E.; Kuepfer, Christine; Singer, Jack W.; Fayad, Luis E.

Radiopharmaceutical reimbursement rates

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

IF55

2008-06-04

PREAI

Singer, Jack W.

Phase III trial comparing paclitaxel poliglumex vs docetaxel in the second-line treatment of non-small-cell lung cancer

BRITISH JOURNAL OF CANCER

IF6.8

2008-05-13

142

OAAI

Paz-Ares, L.; Ross, H.; O'Brien, M.; Riviere, A.; Gatzemeier, U.; Von Pawel, J.; Kaukel, E.; Freitag, L.; Digel, W.; Bischoff, H.; Garcia-Campelo, R.; Iannotti, N.; Reiterer, P.; Bover, I.; Prendiville, J.; Eisenfeld, A. J.; Oldham, F. B.; Bandstra, B.; Singer, J. W.; Bonomi, P.

Cul3 is required for stem cell differentiation and prevents the generation of hepatic tumor stem cells

JOURNAL OF HEPATOLOGY

IF33

2008-01-01

PREAI

Kossatz, U.; Singer, J.; Manns, M.; Malek, N.

Biological and clinical characterization of paclitaxel poliglumex (PPX, CT-2103), a macromolecular polymer-drug conjugate

INTERNATIONAL JOURNAL OF NANOMEDICINE

IF6.5

2006-12-01

130

OAAI

Chipman, Stewart D.; Oldham, Fred B.; Pezzoni, Gabriella; Singer, Jack W.

Antileukemic activity of lysophosphatidic acid acyltransferase-β inhibitor CT32228 in chronic myelogenous leukemia sensitive and resistant to imatinib

CLINICAL CANCER RESEARCH

IF10.2

2006-11-03

OAAI

La Rosee, Paul; Jia, Taiping; Demehri, Shadmer; Haertel, Nicolai; de Vries, Peter; Bonham, Lynn; Hollenback, David; Singer, Jack W.; Melo, Junia V.; Druker, Brian J.; Deininger, Michael W.

研究方向