Leon P. Pybus - Publications, H-index & Citations

Leon P. Pybus

Pontificia Universidad Catolica de Chile

9H指数

24论文数

494被引数

收录论文 12

发表时间

Engineering TPT1-mediated apoptosis resistance for improved mammalian cell biomanufacturing 利用TPT1介导的凋亡抗性工程改造以改善哺乳动物细胞生物制造

Metabolic Engineering

IF6.8

2026-09-01

PREAI

Bravo-Venegas, Javier; Betts, Zeynep; Kalsi, Devika; Pybus, Leon P.; Orellana, Camila A.; Altamirano, Claudia; Dickson, Alan J.; Torres, Mauro

Reconstruction of arginine deiminase pathway sustains a higher-energy state in mammalian cells 精氨酸脱亚胺酶通路的重构在哺乳动物细胞中维持更高的能量状态

Metabolic Engineering

IF6.8

2026-02-10

OAAI

Mauro Torres; Matthew Reaney; Kate Meeson; Devika Kalsi; Leon P. Pybus; Alan J. Dickson

From Discovery to Delivery: A Rapid and Targeted Proteomics Workflow for Monitoring Chinese Hamster Ovary Biomanufacturing 从发现到交付：一种用于监测中国仓鼠卵巢生物制造的快速且靶向的蛋白质组学工作流程

Molecular & Cellular Proteomics

IF5.5

2025-06-01

OAAI

Charles Eldrid; Ellie Hawke; Kathleen M. Cain; Kate Meeson; Joanne Watson; Reynard Spiess; Luke Johnston; William Smith; Matthew Russell; Robyn Hoare; John Raven; Jean-Marc Schwartz; Magnus Rattray; Leon Pybus; Alan Dickson; Andrew Pitt; Perdita Barran

Flux Sampling Suggests Metabolic Signatures of High Antibody-Producing CHO Cells

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2025-04-01

OAAI

Meeson, Kate E.; Watson, Joanne; Rosser, Susan; Hawke, Ellie; Pitt, Andrew; Moses, Tessa; Pybus, Leon; Rattray, Magnus; Dickson, Alan J.; Schwartz, Jean-Marc

Use of tRNA gene barriers improves stability of transgene expression in CHO cells tRNA基因屏障的使用提高了CHO细胞中转基因表达的稳定性

BIOTECHNOLOGY JOURNAL

IF3.1

2024-08-08

OAAI

Sizer, Rebecca E.; Ingram, Richard M.; Swan, Caroline; Biggs, Emma K.; Pybus, Leon P.; White, Robert J.

Dissecting cell death pathways in fed-batch bioreactors

BIOTECHNOLOGY JOURNAL

IF3.1

2023-12-07

OAAI

Mentlak, David A.; Raven, John; Moses, Tessa; Massie, Fraser; Barber, Nicholas; Hoare, Robyn; Burton, Graeme; Young, Alison; Pybus, Leon P.; Rosser, Susan; White, Robert J.; Ungar, Daniel; Bryant, Nia J.

Coupling picodroplet microfluidics with plate imaging for the rapid creation of biomanufacturing suitable cell lines with high probability and improved multi-step assurance of monoclonality

BIOTECHNOLOGY JOURNAL

IF3.1

2021-10-25

PREAI

Pybus, Leon P.; Kalsi, Devika; Matthews, Joe T.; Hawke, Ellie; Barber, Nicholas; Richer, Rachel; Young, Alison; Saunders, Fay L.

Microbioreactor for lower cost and faster optimisation of protein production

ANALYST

IF3.3

2020-01-01

OAAI

Parekh, Mayur; Ali, AbdulAziz; Ali, Zulfiqur; Bateson, Simon; Abugchem, Fathi; Pybus, Leon; Lennon, Christopher