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Clinical benefit and predictors of response to momelotinib after ruxolitinib failure: A cooperative real-world study 美洛替尼在鲁索利替尼治疗失败后的临床获益及疗效预测因素：一项合作性真实世界研究 Francesca Palandri MD, PhD; Monia Marchetti MD, PhD; Elena M. Elli MD; Alessandro Isidori MD; Ilaria Gianesello MD; Chiara Sartor MD, PhD; Novella Pugliese MD; Maria Di Perna MD; Erika Morsia MD; Susanna Gallo MD; Federico Itri MD; Vittorio Montefusco MD; Elena Crisà MD; Annalisa Biagi MD; Eloise Beggiato MD; Olga Mulas MD, PhD; Giulia Benevolo MD; Elisabetta Abruzzese MD; Marco Santoro MD; Alessandra Iurlo MD; Elisabetta Calistri MD; Marco Rossi MD; Bruno Martino MD; Mario Tiribelli MD, PhD; Carmen Fava MD, PhD; Arbana Dizdari MD; Monica Crugnola MD; Andrea Duminuco MD, PhD; Amedeo Votto MD; Selene Guerzoni MD; Giovanni Caocci MD, PhD; Fabrizio Pane MD, PhD; Francesco Lanza MD, PhD; Filippo Branzanti MSc; Alessandra Dedola MD; Flavia Salvatore MD; Florian H. Heidel MD, PhD; Massimo Breccia MD, PhD; Giuseppe A. Palumbo MD, PhD; Andrew T. Kuykendall MD; Alessandro Lucchesi MD, PhD; Sara Galimberti MD, PhD 分享 收藏
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SETD2 loss of function is a recurrent event in advanced-phase chronic myeloid leukemia and contributes to genomic instability SETD2功能缺失是进展期慢性髓性白血病中的常见事件，并导致基因组不稳定。 Mancini, Manuela; De Santis, Sara; Monaldi, Cecilia; Castagnetti, Fausto; Iezza, Miriam; Iurlo, Alessandra; Cattaneo, Daniele; Galimberti, Sara; Cerrano, Marco; Capodanno, Isabella; Bonifacio, Massimiliano; Rossi, Maura; Agostinelli, Claudio; Meggendorfer, Manja; Haferlach, Torsten; Cavo, Michele; Gugliotta, Gabriele; Soverini, Simona 分享 收藏
Circulating Levels of PF4/CXCL4 in Patients With BCR::ABL1-Negative Myeloproliferative Neoplasms: A New Potential Prognostic Factor for Disease Progression BCR::ABL1阴性骨髓增殖性肿瘤患者中PF4/CXCL4的循环水平：疾病进展的一个新的潜在预后因素 Bellani, Valentina; Cattaneo, Daniele; Abbonante, Vittorio; Bucelli, Cristina; Stella, Simona; Mora, Barbara; Malara, Alessandro; Gianelli, Umberto; Balduini, Alessandra; Iurlo, Alessandra 分享 收藏
Bone Marrow CD34+/lin- Cells of Patients with Chronic-Phase Chronic Myeloid Leukemia (CP-CML) After 12 Months of Nilotinib Treatment Exhibit a Different Gene Expression Signature Compared to the Diagnosis and the Corresponding Cells from Healthy Subjects 慢性期慢性髓性白血病（CP-CML）患者接受尼洛替尼治疗12个月后的骨髓CD34+/lin-细胞，其基因表达特征与诊断时及健康受试者对应的细胞存在差异。 Trojani, Alessandra; Pungolino, Ester; Di Camillo, Barbara; Bossi, Luca Emanuele; Palumbo, Cassandra; D'adda, Mariella; Perego, Alessandra; Turrini, Mauro; Elena, Chiara; Borin, Lorenza Maria; Iurlo, Alessandra; Malato, Simona; Spina, Francesco; Latargia, Maria Luisa; Spedini, Pierangelo; Artale, Salvatore; Anghilieri, Michela; Carraro, Maria Cristina; Bucelli, Cristina; Beghini, Alessandro; Cairoli, Roberto 分享 收藏
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Long-Term Safety and Effectiveness of Ponatinib Treatment in Patients with TKI Intolerance: Subgroup Analysis of the Observational Study of Ponatinib Treatment in Patients with CML in Italy (OITI) Ponatinib治疗在TKI不耐受患者中的长期安全性和有效性：意大利慢性粒细胞白血病患者Ponatinib治疗观察研究（OITI）的亚组分析 Breccia, Massimo; Iurlo, Alessandra; Pane, Fabrizio; Scortechini, Anna Rita; Attolico, Immacolata; Santoro, Marco; Cerrano, Marco; Lunghi, Francesca; Maggi, Alessandro; Di Renzo, Nicola; Sargentini, Valeria; Piciocchi, Alfonso; Tringali, Claudia; Malato, Alessandra 分享 收藏
Tyrosine Kinase Inhibitors Discontinuation in Chronic Myeloid Leukemia: Observational Study of 673 Patients in Italy 酪氨酸激酶抑制剂在慢性髓性白血病中的停药：意大利673例患者的观察性研究 Bonuomo, Valentina; Koumantakis, Emanuele; Grano, Selene; Berchialla, Paola; Castagnetti, Fausto; Martino, Bruno; Elena, Chiara; Bocchia, Monica; Capodanno, Isabella; Intermesoli, Tamara; Miggiano, Maria Cristina; Gambacorti-Passerini, Carlo; Iurlo, Alessandra; Lunghi, Francesca; Luciano, Luigiana; Abruzzese, Elisabetta; Carella, Angelo Michele; Breccia, Massimo; Ferrara, Felicetto; Crescenzi, Sabrina Leonetti; Scappini, Barbara; De Gobbi, Marco; Sora, Federica; Rapezzi, Davide; Luzi, Debora; Galimberti, Sara; Crugnola, Monica; Scortechini, Anna Rita; Maggi, Alessandro; Bonifacio, Massimiliano; Annunziata, Mario; Caocci, Giovanni; Beltrami, Germana; Cavazzini, Francesco; Pietrantuono, Giuseppe; Campiotti, Leonardo; Stagno, Fabio; Musolino, Caterina; Cilloni, Daniela; Saglio, Giuseppe; Fava, Carmen 分享 收藏
Baseline Features, Treatment Choice and Early Frontline TKI Permanent Discontinuation in Patients with Newly Diagnosed Chronic Myeloid Leukemia Aged 50-60 Years: A Campus CML Study 基线特征、治疗选择及早期一线TKI永久停药在50-60岁新诊断慢性髓性白血病患者中的研究：一项Campus CML研究 Latagliata, Roberto; Capodanno, Isabella; Miggiano, Maria Cristina; Bucelli, Cristina; Crescenzi, Sabrina Leonetti; Russo, Sabina; Carmosino, Ida; Romano, Atelda; Sora, Federica; Bonifacio, Massimiliano; Luciano, Luigiana; Caocci, Giovanni; Loglisci, Giuseppina; Elena, Chiara; Lunghi, Francesca; Mullai, Rikard; Attolico, Immacolata; Binotto, Gianni; Crisa, Elena; Sportoletti, Paolo; Cavazzini, Francesco; Di Veroli, Ambra; Scortechini, Anna Rita; Leporace, Anna Paola; Maggi, Alessandro; Crugnola, Monica; Stagno, Fabio; Santoro, Marco; Murgano, Pamela; Rapezzi, Davide; Luzi, Debora; Vincelli, Jolanda Donatella; Galimberti, Sara; Bocchia, Monica; Fava, Carmen; Malato, Alessandra; Abruzzese, Elisabetta; Pizzuti, Michele; Iurlo, Alessandra; Saglio, Giuseppe; Specchia, Giorgina; Breccia, Massimo; Tiribelli, Mario 分享 收藏
Cytokine Modulation Correlates Strongly with Symptom Improvement in Patients with Myelofibrosis Treated with Nuvisertib (TP-3654), an Investigational Selective PIM1 Kinase Inhibitor 细胞因子调节与接受Nuvisertib（TP-3654）治疗骨髓纤维化患者的症状改善显著相关，Nuvisertib是一种在研的选择性PIM1激酶抑制剂。 Rein, Lindsay A. M.; El Chaer, Firas; Yuda, Junichiro; Shimoda, Kazuya; Rampal, Raajit; Scandura, Joseph M.; Takami, Akiyoshi; Mccloskey, James; Ichii, Michiko; Shirane, Shuichi; Iurlo, Alessandra; Bose, Prithviraj; Lucchesi, Alessandro; Benevolo, Giulia; Amanam, Idoroenyi; Vachhani, Pankit; Tantravahi, Srinivas K.; Rotta, Marcello; Onishi, Yasushi; Kiladjian, Jean-Jacques; Rinaldi, Ciro; Granacher, Nikki; Bradley, Terrence; Patel, Anand Ashwin; Loschi, Michael; Alimam, Samah; Cheung, Stanley; Ribrag, Vincent; Kabir, Sujan; Seki, Masataka; Pharmd, Karen Ansaldo; Guffanti, Guia; Lee, Jinny; Warner, Steven L.; Foulks, Jason M.; Mesa, Ruben 分享 收藏
Efficacy and safety of fedratinib in patients with myelofibrosis previously treated with ruxolitinib (FREEDOM2): results from a multicentre, open-label, randomised, controlled, phase 3trial Harrison, Claire N.; Mesa, Ruben; Talpaz, Moshe; Al-Ali, Haifa Kathrin; Xicoy, Blanca; Passamonti, Francesco; Palandri, Francesca; Benevolo, Giulia; Vannucchi, Alessandro Maria; Mediavilla, Clemence; Iurlo, Alessandra; Kim, Inho; Rose, Shelonitda; Brown, Patrick; Hernandez, Christopher; Wang, Jia; Kiladjian, Jean-Jacques 分享 收藏
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