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Event-free survival in early polycythemia vera patients correlates with molecular response to ropeginterferon alfa-2b or hydroxyurea/best available therapy (PROUD-PV/CONTINUATION-PV) 早期真性红细胞增多症患者的无事件生存率与对alfa-2b或羟基脲/最佳可用疗法 (PROUD-PV/CONTINUATION-PV) 的分子反应相关 Kiladjian, Jean-Jacques; Klade, Christoph; Georgiev, Pencho; Krochmalczyk, Dorota; Gercheva-Kyuchukova, Liana; Egyed, Miklos; Dulicek, Petr; Illes, Arpad; Pylypenko, Halyna; Sivcheva, Lylia; Mayer, Jiri; Yablokova, Vera; Krejcy, Kurt; Empson, Victoria; Hasselbalch, Hans C.; Kralovics, Robert; Gisslinger, Heinz 分享 收藏
Pelabresib plus ruxolitinib for JAK inhibitor-naive myelofibrosis: a randomized phase 3 trial Pelabresib联合ruxolitinib治疗JAK抑制剂初治骨髓纤维化：一项随机III期试验 Rampal, Raajit K.; Grosicki, Sebastian; Chraniuk, Dominik; Abruzzese, Elisabetta; Bose, Prithviraj; Gerds, Aaron T.; Vannucchi, Alessandro M.; Palandri, Francesca; Lee, Sung-Eun; Gupta, Vikas; Lucchesi, Alessandro; Oh, Stephen T.; Kuykendall, Andrew T.; Patriarca, Andrea; alvarez-Larran, Alberto; Mesa, Ruben; Kiladjian, Jean-Jacques; Talpaz, Moshe; Scandura, Joseph M.; Lavie, David; Harris, Morgan; Kays, Sarah-Katharina; Li, Qing; Boxhammer, Rainer; Brown, Barbara; Jegg, Anna-Maria; Harrison, Claire N.; Mascarenhas, John 分享 收藏
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Comprehensive analysis of mesenchymal cells reveals a dysregulated TGF-β/WNT/ HOXB7 axis in patients with myelofibrosis Ganesan, Saravanan; Awan-Toor, Sarah; Guidez, Fabien; Maslah, Nabih; Rahimy, Rifkath; Aoun, Celine; Gou, Panhong; Guiguen, Chloe; Soret, Juliette; Ravdan, Odonchimeg; Bisio, Valeria; Dulphy, Nicolas; Lobry, Camille; Schlageter, Marie-Helene; Souyri, Michele; Giraudier, Stephane; Kiladjian, Jean-Jacques; Chomienne, Christine; Cassinat, Bruno 分享 收藏
Biomarkers of Renal Health in Patients (pts) Treated with Fedratinib in the FREEDOM and FREEDOM2 Trials Fedratinib治疗的FREEDOM和FREEDOM2试验中患者的肾脏健康生物标志物 Gupta, Vikas; Chen, Yizhe; Brown, Patrick; Jeyaraju, Danny; Talpaz, Moshe; Mesa, Ruben; Pilot, Richard; Hernandez, Christopher; Wang, Jia; Kiladjian, Jean-Jacques; Vannucchi, Alessandro; Harrison, Claire 分享 收藏
ROP-ET: A Prospective Phase III Trial Investigating the Efficacy and Safety of Ropeginterferon Alfa-2b in Essential Thrombocythemia Patients with Limited Treatment Options ROP-ET：一项前瞻性III期试验，旨在研究罗普司坦alfa-2b在治疗治疗选择有限的真性红细胞增多症患者中的有效性和安全性 Kiladjian, Jean-Jacques; Marin, Francisca Ferrer; Al-Ali, Haifa Kathrin; Alvarez-Larran, Alberto; Beggiato, Eloise; Bieniaszewska, Maria; Breccia, Massimo; Buxhofer-Ausch, Veronika; Cerna, Olga; Crisan, Ana Manuela; Danaila, Catalin; De Stefano, Valerio; Dohner, Konstanze; Empson, Victoria; Tybor, Joanna Gora; Griesshammer, Martin; Grosicki, Sebastian; Guglielmelli, Paola; Gutierrez Sr, Valentin Garcia; Heidel, Florian; Illes, Arpad; James, Chloe; Koschmieder, Steffen; Maria-Theresa, Krauth; Krejcy, Kurt; Lazaroiu, Mihaela Cornelia; Mayer, Jiri; Nagy, Zsolt; Palandri, Francesca; Pappa, Vasiliki; Reiter, Andreas; Sacha, Tomasz; Schlager, Stefanie; Schmidt, Stefan Ulrich; Terpos, Evangelos; Tomuleasa, Ciprian; Torregrosa, Jose Miguel; Unger, Martin; Woelfler, Albert; Xicoy, Blanca; Klade, Christoph 分享 收藏
Odyssey: A First-in-Human Study of the Aldehyde Dehydrogenase (ALDH) Inhibitor Abd-3001 in Patients with Refractory/Relapsed Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS) 奥德赛研究：一项关于醛脱氢酶（ALDH）抑制剂Abd-3001在难治/复发性急性髓系白血病（AML）或高风险骨髓增生异常综合征（MDS）患者中的首次人体研究 Benajiba, Lina; Colle, Julien; Heiblig, Mael; Loron, Sandrine; Soret-Dulphy, Juliette; Berchard, Paul; Yazir, Muhube; Basset, Laurent; Venton, Geoffroy; Larcher, Marie-Virginie; De Oliveira, Rafael Daltro; Fossard, Gaelle; Martin, Guillaume; Perez, Mileidys; Ceylan, Ismael; Pelletier, Annick; Kiladjian, Jean-Jacques; Costello, Regis 分享 收藏
Imetelstat Versus Best Available Therapy in Patients with Intermediate-2 or High-Risk Myelofibrosis Relapsed or Refractory to Janus Kinase Inhibitor in IMpactMF, a Randomized, Open-Label, Phase 3 Trial 伊美特尔stat 与最佳可用疗法在 IMpactMF 随机、开放标签、III 期试验中对接受过或难治于 Janus 激酶抑制剂的中间-2 或高风险骨髓纤维化患者中的比较 Mascarenhas, John O.; Harrison, Claire; Bose, Prithviraj; Kiladjian, Jean-Jacques; Lucchesi, Alessandro; Vannucchi, Alessandro Maria; Berry, Tymara; Riggs, Jennifer; Peng, Lixian; Huang, Fei; Wan, Ying; Rodolf, Vivian; Ho, Judy; Navada, Shyamala; Komrokji, Rami S. 分享 收藏
SH283 L oss of Function Variants Are Potential Drivers of Severe Thrombocytosis Awan-Toor, Sarah; Castorena, Jimena; Clay, Denis; Soret-Dulphy, Juliette; De Oliveira, Rafael Daltro; Drouet, Ludovic; Pasquer, Helene; Luque-Paz, Damien; Ugo, Valerie; Verger, Emmanuelle; Maslah, Nabih; Benajiba, Lina; Giraudier, Stephane; Kiladjian, Jean-Jacques; Cassinat, Bruno; Velazquez, Laura 分享 收藏
Updated Results from the Phase 3 Manifest-2 Study of Pelabresib in Combination with Ruxolitinib for Janus Kinase Inhibitor-Naive Patients with Myelofibrosis 佩拉布雷昔布与鲁索利替尼联合治疗Janus激酶抑制剂初治骨髓纤维化患者的III期Manifest-2研究最新结果 Mascarenhas, John O.; Grosicki, Sebastian; Chraniuk, Dominik; Abruzzese, Elisabetta; Bose, Prithviraj; Gerds, Aaron T.; Vannucchi, Alessandro M.; Palandri, Francesca; Lee, Sung-Eun; Gupta, Vikas; Lucchesi, Alessandro; Oh, Stephen; Kuykendall, Andrew T.; Patriarca, Andrea; Alvarez-Larran, Alberto; Mesa, Ruben; Kiladjian, Jean-Jacques; Talpaz, Moshe; Harris, Morgan; Kays, Sarah-Katharina; Li, Qing; Brown, Barbara; Jegg, Anna-Maria; Harrison, Claire; Rampal, Raajit 分享 收藏
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