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Genetic/Familial High-Risk Assessment: Breast, Ovarian, Pancreatic, and Prostate, Version 2.2026 Featured Updates to the NCCN Guidelines 陈, H.H.; 吉里, V.N.; 戈根斯, M.; 尤尔格伦, M.B.; 卡兰, B.Y.; 诺奎斯特, B.S.; 戴利, M.B.; 帕尔, T.; 阿利利, Z.; 阿伦, B.; 等. NCCN指南(R)要点:遗传/家族高风险评估:乳腺、卵巢、胰腺和前列腺,版本2.2026. J. Natl. Compr. Cancer Netw. 2026, 24, 2–10. [Google Scholar] [CrossRef] [PubMed] Cheng, Heather H.; Giri, Veda N.; Goggins, Michael; Yurgelun, Matthew B.; Karlan, Beth Y.; Norquist, Barbara S.; Daly, Mary B.; Pal, Tuya; Alhilli, Zahraa; Arun, Banu; Churpek, Jane; Colonna, Sarah; Domchek, Susan M.; Escobar, Mauricio R.; Fejerman, Laura; Friedman, Susan; Hagemann, Andrea; Hendrix, Ashley; Huo, Dezheng; Hutton, Mollie L.; Kassem, Nawal; Khan, Seema; Kurian, Allison W.; Laronga, Christine; Mak, Julie S.; Maxwell, Kara N.; Mcdonnell, Kevin; Merajver, Sofia D.; Mersch, Jacqueline; Offit, Kenneth; Plichta, Jennifer; Rash, Dominique; Reiser, Gwen; Senter-Jamieson, Leigha; Shannon, Kristen Mahoney; Welborn, Jeanna; Wick, Myra J.; Wood, Marie; Darlow, Susan; Diwan, Zeenat; Dwyer, Mary 分享 收藏
PRECISION ONCOLOGY FOR HIGH-GRADE GLIOMAS: A TUMOR ORGANOID PLATFORM FOR RAPID, PATIENT-SPECIFIC DRUG SCREENING 高分级胶质瘤的精准肿瘤学：一种用于快速、患者特异性药物筛选的肿瘤类器官平台 Tripathy, Arushi; Ji, Sunjong; Alomary, Yazen; Raghunathan, Reka Chakravarthy; Syed, Safiulla; Ravikumar, Visweswaran; Shankar, Sunita; Serhan, Habib; Huang, Dah-Luen; Hara, Toshiro; Clarke, Nathan; Koschmann, Carl; Merrill, Nathan; Merajver, Sofia; Al-Holou, Wajd 分享 收藏
Patient-derived tumor-oids recapitulate the tumor microenvironment and allow for pre-clinical drug screening across the entire spectrum of pediatric brain tumors 患者来源的类器官能够重现肿瘤微环境，并允许对整个谱系的儿童脑肿瘤进行临床前药物筛选。 Wink, Kelsey; Adam, Tiffany; Serhan, Habib; Beale, David R.; Beck, Maxwell; Wadden, Jack; Gehrand, Ashley; Prensner, John; Upadhyaya, Santhosh; Franson, Andrea; Chen, Kevin; Marupudi, Neena; Garton, Hugh; Magge, Suresh N.; Al-Holou, Wajd; Venneti, Sriram; Mody, Rajen; Chinnaiyan, Arul; Rood, Brian R.; Nazarian, Javad; Mueller, Sabine; Mitra, Siddhartha; Green, Adam L.; Kraya, Adam; Merrill, Nathan; Merajver, Sofia D.; Resnick, Adam; Koptyra, Mateus; Koschmann, Carl 分享 收藏
Combinatorial targeting of avapritinib-driven MAPK activation in pediatric high-grade glioma 阿伐普利尼布诱导的MAPK激活在儿童高级别胶质瘤中的组合靶向治疗 Schwark, Kallen; Miclea, Madeline; Patel, Tirth; Kong, Seongbae; Stanczak, Alina; Lau, Benison; Cartaxo, Rodrigo; Messinger, Dana; Doherty, Robert; Ji, Sunjong; Wadden, Jack; Clausen, Madison; Momen, Fareen; Adam, Tiffany; Wink, Kelsey; Hutchinson, Aria; Niculcea, Michael; Serhan, Habib; Merrill, Nathan; Edmonds, Amy; Mayr, Lisa; Neyazi, Sina; Munoz, Denise; Nuechterlein, Nicholas; Fernandez, Ester Calvo; Califano, Andrea; Pavisic, Jovana; Garton, Hugh; Rao, Rama; Upadhyaya, Santhosh; Skrypek, Mary; Bendel, Anne; Lobbous, Mina; Klawinski, Darren; Merajver, Sofia; Koptyra, Mateusz; Resnick, Adam; Nazarian, Javad; Venneti, Sriram; Waszak, Sebastian; Chavez, Lukas; Beck, Alexander; Gojo, Johannes; Filbin, Mariella; Coppe, Jean-Philippe; Koschmann, Carl 分享 收藏
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Unraveling complexity and leveraging opportunities in uncommon breast cancer subtypes Pareja, Fresia; Bhargava, Rohit; Borges, Virginia F.; Brogi, Edi; Canas Marques, Rita; Cardoso, Fatima; Desmedt, Christine; Harigopal, Malini; Lakhani, Sunil R.; Lee, Adrian; Leone, Jose Pablo; Linden, Hannah; Lord, Christopher J.; Marchio, Caterina; Merajver, Sofia D.; Rakha, Emad; Reis-Filho, Jorge S.; Richardson, Andrea; Sawyer, Elinor; Schedin, Pepper; Schwartz, Christopher J.; Tutt, Andrew; Ueno, Naoto T.; Vincent-Salomon, Anne; Weigelt, Britta; Wen, Y. Hannah; Schnitt, Stuart J.; Oesterreich, Steffi 分享 收藏
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Characterization of circulating tumor cells in patients with metastatic bladder cancer utilizing functionalized microfluidics Niu, Zeqi; Kozminsky, Molly; Day, Kathleen C.; Broses, Luke J.; Henderson, Marian L.; Patsalis, Christopher; Tagett, Rebecca; Qin, Zhaoping; Blumberg, Sarah; Reichert, Zachery R.; Merajver, Sofia D.; Udager, Aaron M.; Palmbos, Phillip L.; Nagrath, Sunitha; Day, Mark L. 分享 收藏
Targeting fatty acid synthase in preclinical models of TNBC brain metastases synergizes with SN-38 and impairs invasion Serhan, Habib A.; Bao, Liwei; Cheng, Xu; Qin, Zhaoping; Liu, Chia-Jen; Heth, Jason A.; Udager, Aaron M.; Soellner, Matthew B.; Merajver, Sofia D.; Morikawa, Aki; Merrill, Nathan M. 分享 收藏
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Molecular correlates of drug response to guide therapy in triple-negative breast cancer Merrill, Nathan; Vandecan, Nathalie; Apfel, Athena; Serhan, Habib; Ulintz, Peter; Bao, Liwei; Cheng, Xu; Morikawa, Aki; Merajver, Sofia; Soellner, Matthew 分享 收藏
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Malic enzyme 2 inhibition reveals metabolic vulnerability in serinedependent triple-negative breast cancer Slayton, Mark D.; Farah, Zackariah A.; Jeon, Jin Heon; Achreja, Abhinav; Krinkel, Ben; Nilaj, Brisilda; Eu, Yi-Hsien; Sung, Justin; Rosenfeld, Alyssa; Lui, Alisa; Collard, Mason; Bao, Liwei; Cheng, Xu; Kleer, Celina; Loomes, Kerry; Nagrath, Deepak; Merajver, Sofia D. 分享 收藏
Longitudinal multi-omics characterization of circulating tumor cells from ALK positive NSCLC patients Chen, Yuru; Fouladdel, Shamileh; Ball, Harrison; Qin, Zhaoping; Liu, Albert; Cheng, Xu; Bao, Liwei; Serhan, Habib; Vandenburg, Bryce; Kathawate, Varun; Goo, Larua; Ulintz, Peter; Merrill, Nathan; Udager, Aaron; Qin, Angel; Merajver, Sofia D.; Nagrath, Sunitha 分享 收藏
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Precision medicine-based platform to guide the treatment of EML4-ALK fusion lung cancers and other NSCLC Merrill, Nathan M.; Udager, Aaron; Qin, Angel; Lagisetty, Kiran; Bao, Liwei; Cheng, Xu; Madhi, Hamadi; Banerjee, Ananya; Jahromi, Marziyeh Salehi; Goo, Laura; Kathawate, Varun; Vandenburg, Bryce; Aikins, Marisa; Slayton, Mark; Ulintz, Peter; Qin, Zhaoping; Liu, Chia-Jen; Serhan, Habib; Jefferies, John; Ali, Muhammad Sajawal; Navani, Vishal; Monument, Michael; Kratz, Johannes; Smith, Amber; Chang, Andrew; Kalemkerian, Gregory; Nagrath, Sunitha; Hsu, Peggy; Soellner, Matthew B.; Merajver, Sofia D. 分享 收藏
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