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The Combination of Asciminib with ATP Competing Tyrosine Kinase Inhibitors Might Overcome the Negative Impact of ASXL1 Mutations on Molecular Response in Newly Diagnosed CML Patients Asciminib与ATP竞争性酪氨酸激酶抑制剂的联合应用可能克服ASXL1突变对初诊CML患者分子反应的负面影响。 Ernst, Thomas; Rinke, Jenny; le Coutre, Philipp; Crysandt, Martina; Brummendorf, Tim H. H.; Burchert, Andreas; Lang, Fabian; Saussele, Susanne; Pfirrmann, Markus; Lang, Thomas; Fabisch, Christian; Hochhaus, Andreas 分享 收藏
Health-related quality of life and symptoms of chronic myeloid leukemia patients after discontinuation of tyrosine kinase inhibitors: results from the EURO-SKI Trial Efficace, Fabio; Mahon, Francois-Xavier; Richter, Johan; Piciocchi, Alfonso; Cipriani, Marta; Nicolini, Franck E.; Mayer, Jiri; Zackova, Daniela; Janssen, Jeroen J. W. M.; Panayiotidis, Panayiotis; Vestergaard, Hanne; Koskenvesa, Perttu; Almeida, Antonio; Hjorth-Hansen, Henrik; Martinez-Lopez, Joaquin; Olsson-Stromberg, Ulla; Hochhaus, Andreas; Berger, Marc G.; Etienne, Gabriel; Klamova, Hana; Faber, Edgar; Rousselot, Philippe; Pfirrmann, Markus; Saussele, Susanne 分享 收藏
Management and outcome of patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era - analysis of the European LeukemiaNet Blast Phase Registry Brioli, Annamaria; Lomaia, Elza; Fabisch, Christian; Sacha, Tomasz; Klamova, Hana; Morozova, Elena; Golos, Aleksandra; Ernst, Philipp; Olsson-Stromberg, Ulla; Zackova, Daniela; Nicolini, Franck E.; Bao, Han; Castagnetti, Fausto; Patkowska, Elzbieta; Mayer, Jiri; Hirschbuehl, Klaus; Podgornik, Helena; Paczkowska, Edyta; Parry, Anne; Ernst, Thomas; Voskanyan, Astghik; Szczepanek, Elzbieta; Saussele, Susanne; Franke, Georg-Nikolaus; Kiani, Alexander; Faber, Edgar; Krause, Stefan; Casado, Luis Felipe; Lewandowski, Krzysztof; Eder, Matthias; Anhut, Peter; Gil, Justyna; Suedhoff, Thomas; Hebart, Holger; Heibl, Sonja; Pfirrmann, Markus; Hochhaus, Andreas; Lauseker, Michael 分享 收藏
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The SNP rs460089 in the gene promoter of the drug transporter OCTN1 has prognostic value for treatment-free remission in chronic myeloid leukemia patients treated with imatinib 药物转运体OCTN1基因启动子中的SNP rs460089对伊马替尼治疗的慢性粒细胞白血病患者的无治疗缓解具有预后价值 Polakova, Katerina Machova; Albeer, Ali; Polivkova, Vaclava; Krutska, Monika; Vlcanova, Katerina; Curik, Nikola; Fabarius, Alice; Klamova, Hana; Spiess, Birgit; Waller, Cornelius F.; Bruemmendorf, Tim H.; Dengler, Jolanta; Kunzmann, Volker; Burchert, Andreas; Belohlavkova, Petra; Mustjoki, Satu; Faber, Edgar; Mayer, Jiri; Zackova, Daniela; Panayiotidis, Panayiotis; Richter, Johan; Hjorth-Hansen, Henrik; Kaminska, Magdalena; Plonka, Magdalena; Szczepanek, Elzbieta; Szarejko, Monika; Bober, Grazyna; Hus, Iwona; Grzybowska-Izydorczyk, Olga; Wasilewska, Ewa; Paczkowska, Edyta; Niesiobedzka-Krezel, Joanna; Giannopoulos, Krzysztof; Mahon, Francois X.; Sacha, Tomasz; Saussele, Susanne; Pfirrmann, Markus 分享 收藏
Step-in dosing of bosutinib in pts with chronic phase chronic myeloid leukemia (CML) after second-generation tyrosine kinase inhibitor (TKI) therapy: results of the Bosutinib Dose Optimization (BODO) Study 第二代酪氨酸激酶抑制剂 (TKI) 治疗后慢性粒细胞白血病 (CML) 慢性期患者中博舒替尼的逐步剂量: 博舒替尼剂量优化 (BODO) 研究的结果 Isfort, Susanne; Manz, Kirsi L.; Teichmann, Lino; Crysandt, Martina; Burchert, Andreas; Hochhaus, Andreas; Saussele, Susanne; Kiani, Alexander R.; Gothert, Joachim; Illmer, Thomas; Schafhausen, Philippe; Al-Ali, Haifa Kathrin; Stegelmann, Frank; Haenel, Mathias; Pfeiffer, Tim; Giagounidis, Aristoteles; Franke, Georg-Nikolaus; Koschmieder, Steffen; Fabarius, Alice; Ernst, Thomas; Warnken-Uhlich, Mareille; Wolber, Uta; Kohn, Denise; Pfirrmann, Markus; Wolf, Dominik H.; Bruemmendorf, Tim; German CML Study Grp 分享 收藏
The JAK1/2 inhibitor ruxolitinib in patients with COVID-19 triggered hyperinflammation: the RuxCoFlam trial Hammersen, J.; Birndt, S.; Doehner, K.; Reuken, P.; Stallmach, A.; Sauerbrey, P.; La Rosee, F.; Pfirrmann, M.; Fabisch, C.; Weiss, M.; Traeger, K.; Bremer, H.; Russo, S.; Illerhaus, G.; Droemann, D.; Schneider, S.; La Rosee, P.; Hochhaus, A. 分享 收藏
Different treatment strategies versus a common standard arm (CSA) in patients with newly diagnosed AML over the age of 60 years: a randomized German inter-group study 60岁以上新诊断AML患者的不同治疗策略与共同标准臂 (CSA): 一项随机德国组间研究 Niederwieser, Dietger; Lang, Thomas; Krahl, Rainer; Heinicke, Thomas; Maschmeyer, Georg; Al-Ali, Haifa Kathrin; Schwind, Sebastian; Jentzsch, Madlen; Cross, Michael; Kahl, Christoph; Wolf, Hans-Heinrich; Sayer, Herbert; Schulze, Antje; Dreger, Peter; Hegenbart, Ute; Kraemer, Alwin; Junghanss, Christian; Muegge, Lars-Olof; Haehling, Detlev; Hirt, Carsten; Spaeth, Christian; Peter, Norma; Opitz, Bernhard; Florschuetz, Axel; Reifenrath, Kolja; Zojer, Niklas; Scholl, Sebastian; Poenisch, Wolfram; Heyn, Simone; Vucinic, Vladan; Hochhaus, Andreas; Aul, Carlo; Giagounidis, Aristoteles; Balleisen, Leopold; Oldenkott, Bernd; Staib, Peter; Kiehl, Michael; Schuette, Wolfgang; Naumann, Ralph; Eimermacher, Hartmut; Doerken, Bernd; Sauerland, Cristina; Lengfelder, Eva; Hiddemann, Wolfgang; Woermann, Bernhard; Mueller-Tidow, Carsten; Serve, Hubert; Schliemann, Christoph; Hehlmann, Ruediger; Berdel, Wolfgang E.; Pfirrmann, Markus; Krug, Utz; Hoffmann, Verena S. 分享 收藏
ASXL1 mutations predict inferior molecular response to nilotinib treatment in chronic myeloid leukemia Schoenfeld, Lioba; Rinke, Jenny; Hinze, Anna; Nagel, Saskia N.; Schaefer, Vivien; Schenk, Thomas; Fabisch, Christian; Bruemmendorf, Tim H.; Burchert, Andreas; le Coutre, Philipp; Krause, Stefan W.; Saussele, Susanne; Safizadeh, Fatemeh; Pfirrmann, Markus; Hochhaus, Andreas; Ernst, Thomas 分享 收藏
Oral insulin immunotherapy in children at risk for type 1 diabetes in a randomised controlled trial 1型糖尿病高危儿童口服胰岛素免疫治疗的随机对照试验 Assfalg, Robin; Knoop, Jan; Hoffman, Kristi L.; Pfirrmann, Markus; Zapardiel-Gonzalo, Jose Maria; Hofelich, Anna; Eugster, Anne; Weigelt, Marc; Matzke, Claudia; Reinhardt, Julia; Fuchs, Yannick; Bunk, Melanie; Weiss, Andreas; Hippich, Markus; Halfter, Kathrin; Hauck, Stefanie M.; Hasford, Jorg; Petrosino, Joseph F.; Achenbach, Peter; Bonifacio, Ezio; Ziegler, Anette-Gabriele 分享 收藏
High-risk additional chromosomal abnormalities at low blast counts herald death by CML (vol 34, pg 2074, 2020) Hehlmann, Rudiger; Voskanyan, Astghik; Lauseker, Michael; Pfirrmann, Markus; Kalmanti, Lida; Rinaldetti, Sebastien; Kohlbrenner, Katharina; Haferlach, Claudia; Schlegelberger, Brigitte; Fabarius, Alice; Seifarth, Wolfgang; Spiess, Birgit; Wuchter, Patrick; Krause, Stefan; Kolb, Hans-Jochem; Neubauer, Andreas; Hossfeld, Dieter K.; Nerl, Christoph; Gratwohl, Alois; Baerlocher, Gabriela M.; Burchert, Andreas; Bruemmendorf, Tim H.; Hasford, Joerg; Hochhaus, Andreas; Saussele, Susanne; Baccarani, Michele 分享 收藏
The EUTOS long-term survival (ELTS) score is superior to the Sokal score for predicting survival in chronic myeloid leukemia Pfirrmann, Markus; Clark, Richard E.; Prejzner, Witold; Lauseker, Michael; Baccarani, Michele; Saussele, Susanne; Guilhot, Francois; Heibl, Sonja; Hehlmann, Rudiger; Faber, Edgar; Turkina, Anna; Ossenkoppele, Gert; Hoglund, Martin; Zaritskey, Andrey; Griskevicius, Laimonas; Olsson-Stromberg, Ulla; Everaus, Hele; Koskenvesa, Perttu; Labar, Boris; Sacha, Tomasz; Zackova, Daniela; Cervantes, Francisco; Colita, Adriana; Zupan, Irena; Bogdanovic, Andrija; Castagnetti, Fausto; Guilhot, Joelle; Hasford, Joerg; Hochhaus, Andreas; Hoffmann, Verena S. 分享 收藏
High-risk additional chromosomal abnormalities at low blast counts herald death by CML Hehlmann, Ruediger; Voskanyan, Astghik; Lauseker, Michael; Pfirrmann, Markus; Kalmanti, Lida; Rinaldetti, Sebastien; Kohlbrenner, Katharina; Haferlach, Claudia; Schlegelberger, Brigitte; Fabarius, Alice; Seifarth, Wolfgang; Spiess, Birgit; Wuchter, Patrick; Krause, Stefan; Kolb, Hans-Jochem; Neubauer, Andreas; Hossfeld, Dieter K.; Nerl, Christoph; Gratwohl, Alois; Baerlocher, Gabriela M.; Burchert, Andreas; Bruemmendorf, Tim H.; Hasford, Joerg; Hochhaus, Andreas; Saussele, Susanne; Baccarani, Michele 分享 收藏
Prognosis of patients with chronic myeloid leukemia presenting in advanced phase is defined mainly by blast count, but also by age, chromosomal aberrations and hemoglobin Lauseker, Michael; Bachl, Katharina; Turkina, Anna; Faber, Edgar; Prejzner, Witold; Olsson-Stromberg, Ulla; Baccarani, Michele; Lomaia, Elza; Zackova, Daniela; Ossenkoppele, Gert; Griskevicius, Laimonas; Schubert-Fritschle, Gabriele; Sacha, Tomasz; Heibl, Sonja; Koskenvesa, Perttu; Bogdanovic, Andrija; Clark, Richard E.; Guilhot, Joelle; Hoffmann, Verena S.; Hasford, Joerg; Hochhaus, Andreas; Pfirrmann, Markus 分享 收藏
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