Sheila S. David

university of california davis

H指数:44

被引数:7,920

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DNA Damage Recognition by Bacterial and Human Adenine-DNA Glycosylases: Insights from Non-Canonical Substrates

细菌和人类腺嘌呤-DNA糖基酶对DNA损伤的识别：来自非规范底物的见解

Biomolecules

IF4.8

2026-08-270

8oxoG:A Is Structurally Accommodated in the Nucleosome Core Particle, Yet Inaccessible to MUTYH-Initiated DNA Repair

8oxoG:A 在核小体核心颗粒中结构上被容纳，但无法被 MUTYH 介导的 DNA 修复所接近

Biomolecules

IF4.8

2026-07-280

MUTYH Cancer-Associated Variants Within the Interdomain Connector Differentially Impact Glycosylase Activity and Cellular DNA Repair

MUTYH癌症相关变异位于跨域连接器内，对糖基化酶活性和细胞DNA修复具有差异性影响

ChemBioChem

IF2.8

2026-07-100

OAAI

Crystal structure of MutYX: a novel clusterless adenine DNA glycosylase with a distinct C-terminal domain and 8-oxoguanine recognition sphere

MutYX的晶体结构：一种具有独特C端结构域和8-oxoguanine识别区域的全新非集群腺嘌呤DNA糖基化酶

NUCLEIC ACIDS RESEARCH

IF13.1

2025-11-260

OAAI

TP53 Mutations in MDS/AML are Preferentially Propagated Through Erythroid-Committed Progenitors

LABORATORY INVESTIGATION

IF4.2

2025-03-010

PRE

FSHing for DNA Damage: Key Features of MutY Detection of 8-Oxoguanine:Adenine Mismatches

ACCOUNTS OF CHEMICAL RESEARCH

IF17.7

2024-03-120

OAAI

Cellular Repair of Synthetic Analogs of Oxidative DNA Damage Reveals a Key Structure-Activity Relationship of the Cancer-Associated MUTYH DNA Repair Glycosylase

ACS CENTRAL SCIENCE

IF10.4

2024-01-262

OAAI

Structural and biochemical insights into NEIL2's preference for abasic sites

NUCLEIC ACIDS RESEARCH

IF13.1

2023-11-161

OAAI

Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism

NUCLEIC ACIDS RESEARCH

IF13.1

2023-01-129

OAAI

NEIL1 Recoding due to RNA Editing Impacts Lesion-Specific Recognition and Excision

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2022-08-0211

Structure, function and evolution of the Helix-hairpin-Helix DNA glycosylase superfamily: Piecing together the evolutionary puzzle of DNA base damage repair mechanisms

DNA REPAIR

IF2.7

2021-12-0127

OAAI

Single molecule analysis indicates stimulation of MUTYH by UV-DDB through enzyme turnover

NUCLEIC ACIDS RESEARCH

IF13.1

2021-07-0715

OAAI

Unique Hydrogen Bonding of Adenine with the Oxidatively Damaged Base 8-Oxoguanine Enables Specific Recognition and Repair by DNA Glycosylase MutY

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2020-11-1715

OAAI

Designer Fluorescent Adenines Enable Real-Time Monitoring of MUTYH Activity

ACS CENTRAL SCIENCE

IF10.4

2020-08-3113

OAAI

Detection of OG:A Lesion Mispairs by MutY Relies on a Single His Residue and the 2-Amino Group of 8-Oxoguanine

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2020-07-1517

OAAI

The DNA repair enzyme MUTYH potentiates cytotoxicity of the alkylating agent MNNG by interacting with abasic sites

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-03-0110

OAAI

2′-Fluorinated Hydantoins as Chemical Biology Tools for Base Excision Repair Glycosylases

ACS CHEMICAL BIOLOGY

IF3.8

2020-02-188

OAAI

Recognition of DNA adducts by edited and unedited forms of DNA glycosylase NEIL1

DNA REPAIR

IF2.7

2020-01-0129

OAAI

Structural Basis for Finding OG Lesions and Avoiding Undamaged G by the DNA Glycosylase MutY

ACS CHEMICAL BIOLOGY

IF3.8

2019-12-1229

OAAI

When you're strange: Unusual features of the MUTYH glycosylase and implications in cancer

DNA REPAIR

IF2.7

2019-08-0133

OAAI

Sheila S. David

个人简介

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