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Protocol to perform cell-type-specific transcriptomewide association study using scPrediXcan framework 利用scPrediXcan框架进行细胞类型特异性全转录组关联研究的方案 Zhou, Yichao; Sumner, Sarah; Adeluwa, Temidayo; Zhu, Lisha; Salazar-Magan, Sofia; Kim, Hyunki; Gona, Saideep; Nyasimi, Festus; Kulkarni, Rohit; Powell, Joseph; Madduri, Ravi; Liu, Boxiang; Chen, Mengjie; Im, Hae Kyung 分享 收藏
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Multi-INTACT: integrative analysis of the genome, transcriptome, and proteome identifies causal mechanisms of complex traits Multi-INTACT：对基因组、转录组和蛋白质组的整合分析鉴定复杂性状的因果机制 Okamoto, Jeffrey; Yin, Xianyong; Ryan, Brady; Chiou, Joshua; Luca, Francesca; Pique-Regi, Roger; Im, Hae Kyung; Morrison, Jean; Fauman, Eric B.; Laakso, Markku; Boehnke, Michael; Wen, Xiaoquan 分享 收藏
A multi-tissue, splicing-based joint transcriptome-wide association study identifies susceptibility genes for breast cancer Gao, Guimin; McClellan, Julian; Barbeira, Alvaro N.; Fiorica, Peter N.; Li, James L.; Mu, Zepeng; Olopade, Olufunmilayo I.; Huo, Dezheng; Im, Hae Kyung 分享 收藏
Transcriptome-wide association study of the plasma proteome reveals cis and trans regulatory mechanisms underlying complex traits Wittich, Henry; Ardlie, Kristin; Taylor, Kent D.; Durda, Peter; Liu, Yongmei; Mikhaylova, Anna; Gignoux, Chris R.; Cho, Michael H.; Rich, Stephen S.; Rotter, Jerome I.; Manichaikul, N. H. L. B. I. TOPMed Consortium Ani; Im, Hae Kyung; Wheeler, Heather E. 分享 收藏
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Multivariate adaptive shrinkage improves cross-population transcriptome prediction and association studies in underrepresented populations Araujo, Daniel S.; Nguyen, Chris; Hu, Xiaowei; Mikhaylova, Anna, V; Gignoux, Chris; Ardlie, Kristin; Taylor, Kent D.; Durda, Peter; Liu, Yongmei; Papanicolaou, George; Cho, Michael H.; Rich, Stephen S.; Rotter, Jerome I.; Im, Hae Kyung; Manichaikul, Ani; Wheeler, Heather E. 分享 收藏
Predicted Proteome Association Studies of Breast, Prostate, Ovarian, and Endometrial Cancers Implicate Plasma Protein Regulation in Cancer Susceptibility Gregga, Isabelle; Pharoah, Paul D. P.; Gayther, Simon A.; Manichaikul, Ani; Im, Hae Kyung; Kar, Siddhartha P.; Schildkraut, Joellen M.; Wheeler, Heather E. 分享 收藏
The high-dimensional space of human diseases built from diagnosis records and mapped to genetic loci (vol 3, pg 403, 2023) Jia, Gengjie; Li, Yu; Zhong, Xue; Wang, Kanix; Pividori, Milton; Alomairy, Rabab; Esposito, Aniello; Ltaief, Hatem; Terao, Chikashi; Akiyama, Masato; Matsuda, Koichi; Keyes, David E. E.; Im, Hae Kyung; Gojobori, Takashi; Kamatani, Yoichiro; Kubo, Michiaki; Cox, Nancy J. J.; Evans, James; Gao, Xin; Rzhetsky, Andrey 分享 收藏
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Predicting molecular mechanisms of hereditary diseases by using their tissue-selective manifestation 利用遗传性疾病的组织选择性表现预测遗传性疾病的分子机制 Simonovsky, Eyal; Sharon, Moran; Ziv, Maya; Mauer, Omry; Hekselman, Idan; Jubran, Juman; Vinogradov, Ekaterina; Argov, Chanan M.; Basha, Omer; Kerber, Lior; Yogev, Yuval; Segre, Ayellet, V; Im, Hae Kyung; Birk, Ohad; Rokach, Lior; Yeger-Lotem, Esti; GTEx Consortium 分享 收藏
The high-dimensional space of human diseases built from diagnosis records and mapped to genetic loci Jia, Gengjie; Li, Yu; Zhong, Xue; Wang, Kanix; Pividori, Milton; Alomairy, Rabab; Esposito, Aniello; Ltaief, Hatem; Terao, Chikashi; Akiyama, Masato; Matsuda, Koichi; Keyes, David E.; Im, Hae Kyung; Gojobori, Takashi; Kamatani, Yoichiro; Kubo, Michiaki; Cox, Nancy J.; Evans, James; Gao, Xin; Rzhetsky, Andrey 分享 收藏
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Discerning asthma endotypes through comorbidity mapping Jia, Gengjie; Zhong, Xue; Im, Hae Kyung; Schoettler, Nathan; Pividori, Milton; Hogarth, D. Kyle; Sperling, Anne, I; White, Steven R.; Naureckas, Edward T.; Lyttle, Christopher S.; Terao, Chikashi; Kamatani, Yoichiro; Akiyama, Masato; Matsuda, Koichi; Kubo, Michiaki; Cox, Nancy J.; Ober, Carole; Rzhetsky, Andrey; Solway, Julian 分享 收藏
Polygenic transcriptome risk scores for COPD and lung function improve cross-ethnic portability of prediction in the NHLBI TOPMed program Hu, Xiaowei; Qiao, Dandi; Kim, Wonji; Moll, Matthew; Balte, Pallavi P.; Lange, Leslie A.; Bartz, Traci M.; Kumar, Rajesh; Li, Xingnan; Yu, Bing; Cade, Brian E.; Laurie, Cecelia A.; Sofer, Tamar; Ruczinski, Ingo; Nickerson, Deborah A.; Muzny, Donna M.; Metcalf, Ginger A.; Doddapaneni, Harshavardhan; Gabriel, Stacy; Gupta, Namrata; Dugan-Perez, Shannon; Cupples, L. Adrienne; Loehr, Laura R.; Jain, Deepti; Rotter, Jerome, I; Wilson, James G.; Psaty, Bruce M.; Fornage, Myriam; Morrison, Alanna C.; Vasan, Ramachandran S.; Washko, George; Rich, Stephen S.; O'Connor, George T.; Bleecker, Eugene; Kaplan, Robert C.; Kalhan, Ravi; Redline, Susan; Gharib, Sina A.; Meyers, Deborah; Ortega, Victor; Dupuis, Josee; London, Stephanie J.; Lappalainen, Tuuli; Oelsner, Elizabeth C.; Silverman, Edwin K.; Barr, R. Graham; Thornton, Timothy A.; Wheeler, Heather E.; Cho, Michael H.; Im, Hae Kyung; Manichaikul, Ani 分享 收藏
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Pleiotropy-guided transcriptome imputation from normal and tumor tissues identifies candidate susceptibility genes for breast and ovarian cancer 来自正常和肿瘤组织的多效性指导的转录组插补确定了乳腺癌和卵巢癌的候选易感基因 Kar, Siddhartha P.; Considine, Daniel P. C.; Tyrer, Jonathan P.; Plummer, Jasmine T.; Chen, Stephanie; Dezem, Felipe S.; Barbeira, Alvaro N.; Rajagopal, Padma S.; Rosenow, Will T.; Moreno, Fernando; Bodelon, Clara; Chang-Claude, Jenny; Chenevix-Trench, Georgia; DeFazio, Anna; Doerk, Thilo; Ekici, Arif B.; Ewing, Ailith; Fountzilas, George; Goode, Ellen L.; Hartman, Mikael; Heitz, Florian; Hillemanns, Peter; Hogdall, Estrid; Hogdall, Claus K.; Huzarski, Tomasz; Jensen, Allan; Karlan, Beth Y.; Khusnutdinova, Elza; Kiemeney, Lambertus A.; Kjaer, Susanne K.; Klapdor, Rudiger; Kobel, Martin; Li, Jingmei; Liebrich, Clemens; May, Taymaa; Olsson, Hakan; Permuth, Jennifer B.; Peterlongo, Paolo; Radice, Paolo; Ramus, Susan J.; Riggan, Marjorie J.; Risch, Harvey A.; Saloustros, Emmanouil; Simard, Jacques; Szafron, Lukasz M.; Titus, Linda; Thompson, Cheryl L.; Vierkant, Robert A.; Winham, Stacey J.; Zheng, Wei; Doherty, Jennifer A.; Berchuck, Andrew; Lawrenson, Kate; Im, Hae Kyung; Manichaikul, Ani W.; Pharoah, Paul D. P.; Gayther, Simon A.; Schildkraut, Joellen M. 分享 收藏
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