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A

Andrea Ventura

Memorial Sloan Kettering Cancer Center
H指数:38
被引数:1.2万

个人简介

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荣誉奖项

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Micronuclear ecDNA constrains tumor cell fitness and is associated with favorable patient survival

微核中的染色体外DNA限制肿瘤细胞适应性并与患者良好生存相关

Nature Genetics
IF29
2026-10-120
OAAI
Lotte Brückner; Robin Xu; Jun Tang; Aditi Gnanasekar; Alexander Herrmann; Ivy Tsz-Lo Wong; Shu Zhang; Fengyu Tu; Madison Pilon; Alexander Kukalev; Katharina Pardon; Olga Sidorova; Joshua Atta; Qinghao Yu; Giulia Montuori; Davide Pradella; Mila Ilić; Kentaro Suina; Marco Novais-Cruz; Sarah Kaltenbach; Denise Treue; Mădălina Giurgiu-Kraljič; Sergej Herzog; Ann-Sophie Hollinger; Nadine Wittstruck; Martina Fernandez; Nicole Wolozyn; Finnja Becker; Varvara-Rigina Louma; Xiaowei Yan; Rachel Schmargon; Jan R. Dörr; David Gamlin; Annika Lehmann; Dennis Gürgen; Matthias Richter; Frank Dubois; Fabrizio Simeoni; Betheney R. Pennycook; Alastair Hamilton; Ralph K. Lindemann; Courtney Dawes; Gabriel Balmus; Barbara Hero; Matthias Fischer; Vineet Bafna; Roel Verhaak; Geoffrey Wahl; Yang Liu; Richard P. Koche; Stamatis Papathanasiou; René Medema; Bastiaan Spanjaard; Andrea Ventura; Ana Pombo; Weini Huang; Monika Scheer; Benjamin Werner; Howard Y. Chang; Paul S. Mischel; Anton G. Henssen
MMEJ repair of breaks at TA repeats maintains ecDNA and cancer fitness

TA重复序列处的断裂通过MMEJ修复维持了ecDNA和癌细胞适应性

Nature
IF48.5
2026-09-230
OAAI
David Billing; Monica Selvaraj; Megan E. Kelley; Gabriel Matos-Rodrigues; Benton Bailey; Finnja Becker; Gang Zhen; Matthew A. Myers; Alessandra Brambati; Oluchi Ezekwenna; Ashley Nichols; Yi-Zhen Jiang; Lucia Wang; Shih-Chun Wang; Marie-Claude Mathieu; Davide Pradella; Hugo Poirier; Elias Rodriguez-Fos; Stephen J. Morris; Michal Zimmermann; Elsa Callen; Michael Zinda; Andrea Ventura; John Maciejowski; Andrew McPherson; Sohrab P. Shah; Anton George Henssen; André Nussenzweig; Agnel Sfeir
Engineered extrachromosomal oncogene amplifications promote tumorigenesis
Nature
IF48.5
2024-12-180
OAAI
Davide Pradella; Minsi Zhang; Rui Gao; Melissa A. Yao; Katarzyna M. Gluchowska; Ylenia Cendon-Florez; Tanmay Mishra; Gaspare La Rocca; Moritz Weigl; Ziqi Jiao; Hieu H. M. Nguyen; Marta Lisi; Mateusz M. Ozimek; Chiara Mastroleo; Kevin Chen; Felix Grimm; Jens Luebeck; Shu Zhang; Andrea Alice Zolli; Eric G. Sun; Bhargavi Dameracharla; Zhengqiao Zhao; Yuri Pritykin; Carlie Sigel; Howard Y. Chang; Paul S. Mischel; Vineet Bafna; Cristina R. Antonescu; Andrea Ventura
Zurletrectinib is a next-generation TRK inhibitor with strong intracranial activity against NTRK fusion-positive tumours with on-target resistance to first-generation agents
BRITISH JOURNAL OF CANCER
IF6.8
2024-06-200
OA
Roa, Paola; Foglizzo, Valentina; Harada, Guilherme; Repetto, Matteo; Kulick, Amanda; de Stanchina, Elisa; de Marchena, Michelle; Auwardt, Supipi; Ahmed, Shaza Sayed; Bremer, Nicole Virginia; Yang, Soo-Ryum; Feng, Yangbo; Zhou, Chao; Kong, Norman; Liang, Ruixia; Xu, Haipeng; Zhang, Bin; Bardelli, Alberto; Toska, Eneda; Ventura, Andrea; Drilon, Alexander; Cocco, Emiliano
EML4-ALK fusions drive lung adeno-to-squamous transition through JAK-STAT activation
JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2024-01-297
OAAI
Qin, Zhen; Yue, Meiting; Tang, Shijie; Wu, Fengying; Sun, Honghua; Li, Yuan; Zhang, Yongchang; Izumi, Hiroki; Huang, Hsinyi; Wang, Wanying; Xue, Yun; Tong, Xinyuan; Mori, Shunta; Taki, Tetsuro; Goto, Koichi; Jin, Yujuan; Li, Fei; Li, Fu-Ming; Gao, Yijun; Fang, Zhaoyuan; Fang, Yisheng; Hu, Liang; Yan, Xiumin; Xu, Guoliang; Chen, Haiquan; Kobayashi, Susumu S.; Ventura, Andrea; Wong, Kwok-Kin; Zhu, Xueliang; Chen, Liang; Ren, Shengxiang; Chen, Luo-Nan; Ji, Hongbin
Counteracting lineage-specific transcription factor network finely tunes lung adeno-to-squamous transdifferentiation through remodeling tumor immune microenvironment

抵消谱系特异性转录因子网络通过重塑肿瘤免疫微环境精细调节肺腺向鳞状细胞的转分化

NATIONAL SCIENCE REVIEW
IF17.1
2023-02-1417
OAAI
Tang, Shijie; Xue, Yun; Qin, Zhen; Fang, Zhaoyuan; Sun, Yihua; Yuan, Chongzhe; Pan, Yunjian; Zhao, Yue; Tong, Xinyuan; Zhang, Jian; Huang, Hsinyi; Chen, Yuting; Hu, Liang; Huang, Dasong; Wang, Ruiqi; Zou, Weiguo; Li, Yuan; Thomas, Roman K.; Ventura, Andrea; Wong, Kwok-Kin; Chen, Haiquan; Chen, Luonan; Ji, Hongbin
TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors
CANCER DISCOVERY
IF33.3
2021-01-0637
OAAI
Cocco, Emiliano; Lee, Ji Eun; Kannan, Srinivasaraghavan; Schram, Alison M.; Won, Helen H.; Shifman, Sophie; Kulick, Amanda; Baldino, Laura; Toska, Eneda; Arruabarrena-Aristorena, Amaia; Kittane, Srushti; Wu, Fan; Cai, Yanyan; Arena, Sabrina; Mussolin, Benedetta; Kannan, Ram; Vasan, Neil; Gorelick, Alexander N.; Berger, Michael F.; Novoplansky, Ofra; Jagadeeshan, Sankar; Liao, Yi; Rix, Uwe; Misale, Sandra; Taylor, Barry S.; Bardelli, Alberto; Hechtman, Jaclyn F.; Hyman, David M.; Elkabets, Moshe; de Stanchina, Elisa; Verma, Chandra S.; Ventura, Andrea; Drilon, Alexander; Scaltriti, Maurizio
TRK xDFG mutations trigger a sensitivity switch from type I to II kinase inhibitors
CANCER RESEARCH
IF16.6
2020-08-150
PRE
Cocco, Emiliano; Lee, Ji Eun; Kannan, Srinivasaraghavan; Schram, Alison M.; Won, Helen H.; Shifman, Sophie; Kulick, Amanda; Baldino, Laura; Toska, Eneda; Arena, Sabrina; Mussolin, Benedetta; Kannan, Ram; Vasan, Neil; Gorelick, Alexander N.; Berger, Michael F.; Liao, Yi; Rix, Uwe; Bardelli, Alberto; Hechtman, Jacklyn; de Stanchina, Elisa; Hyman, David M.; Verma, Chandra; Ventura, Andrea; Drilon, Alexander; Scaltriti, Maurizio

研究方向

暂未获取到该数据
P
Pier Giuseppe Pelicci
H 指数:125论文数:942被引数:6.2万
J
Joana A. Vidigal
H 指数:14论文数:25被引数:2,540
G
Gaspare La Rocca
H 指数:19论文数:56被引数:1,563
A
Alexander Drilon
H 指数:91论文数:1,386被引数:3.8万
C
Carla P. Concepcion
H 指数:11论文数:75被引数:2,240
R
Ram Kannan
H 指数:6论文数:28被引数:339
M
Maurizio Scaltriti
H 指数:74论文数:665被引数:2.5万
X
Xiaoyi Li
H 指数:19论文数:67被引数:1,203
D
Davide Pradella
H 指数:11论文数:36被引数:871
C
Christina S. Leslie
H 指数:78论文数:351被引数:2.7万