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R

Robert A. Seaborne

kings college london
H指数:17
被引数:1,554

个人简介

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荣誉奖项

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Integrated Single‐Myofibre Multi‐Omics Correlates Inflammatory State to Myosin Energetics in ICU‐Acquired Weakness

整合单肌原纤维多组学将炎症状态与肌球蛋白能量学相关联以解释ICU获得性肌无力

Journal of Cachexia Sarcopenia and Muscle
IF9.1
2026-10-190
OAAI
Alexandra M. Winant; Roger Moreno‐Justicia; Lucia Paolini; Wout J. Claassen; Coen A. C. Ottenheijm; Atul S. Deshmukh; Stefano Cattaneo; Simone Piva; Nicola Latronico; Robert A. E. Seaborne; Julien Ochala
Changes in cardiac myosin acetylation disrupt the super-relaxed state in genotype-negative hypertrophic cardiomyopathy with type 2 diabetes

在2型糖尿病合并基因阴性肥厚型心肌病中，心肌肌球蛋白乙酰化变化破坏了超松弛状态

Cardiovascular Diabetology
IF10.6
2026-05-260
PRE
Edgar E. Nollet; Chahida Chaami; Helena Bogdanovic Keleman; Elise Gerlach Melhedegaard; Christopher T. A. Lewis; Robert A. E. Seaborne; Julia E. Visch; Stephan A. C. Schoonvelde; Miao Feng; Qian Wang; Anthony L. Hessel; Michel N. Kuehn; Bauke V. Schomakers; Michel van Weeghel; Michelle Michels; Diederik W. D. Kuster; Jolanda van der Velden; Julien Ochala
Myosin inhibition partially rescues the myofiber proteome in X-linked myotubular myopathy

肌球蛋白抑制部分恢复了X连锁肌管性肌病的肌原纤维蛋白质组

JCI Insight
IF6.1
2025-12-221
OA
Melhedegaard, Elise Gerlach; Rostedt, Fanny; Gineste, Charlotte; Seaborne, Robert A. E.; Dugdale, Hannah F.; Belhac, Vladimir; Zanoteli, Edmar; Lawlor, Michael W.; Mack, David L.; Wallgren-Pettersson, Carina; Hessel, Anthony L.; Jungbluth, Heinz; Laporte, Jocelyn; Saito, Yoshihiko; Nishino, Ichizo; Ochala, Julien; Laitila, Jenni
Dysregulated skeletal muscle myosin super-relaxation and energetics in male participants with type 2 diabetes mellitus

2型糖尿病男性参与者骨骼肌肌球蛋白超松弛和能量代谢的失调

DIABETOLOGIA
IF10.2
2025-04-280
OA
Lewis, Christopher T. A.; Moreno-Justicia, Roger; Savoure, Lola; Calvo, Enrique; Bak, Agata; Laitila, Jenni; Seaborne, Robert A. E.; Larsen, Steen; Iwamoto, Hiroyuki; Cefis, Marina; Morais, Jose A.; Gouspillou, Gilles; Alegre-Cebollada, Jorge; Hawke, Thomas J.; Vazquez, Jesus; Adrover, Miquel; Marcangeli, Vincent; Hammad, Rami; Granet, Jordan; Gaudreau, Pierrette; Aubertin-Leheudre, Mylene; Belanger, Marc; Robitaille, Richard; Deshmukh, Atul S.; Ochala, Julien
Human skeletal muscle fiber heterogeneity beyond myosin heavy chains

肌球蛋白重链之外的骨骼肌纤维异质性

NATURE COMMUNICATIONS
IF15.7
2025-02-192
OAAI
Roger Moreno-Justicia; Thibaux Van der Stede; Ben Stocks; Jenni Laitila; Robert A. Seaborne; Alexia Van de Loock; Eline Lievens; Diana Samodova; Leyre Marín-Arraiza; Oksana Dmytriyeva; Robin Browaeys; Kim Van Vossel; Lukas Moesgaard; Nurten Yigit; Jasper Anckaert; Anneleen Weyns; Ruud Van Thienen; Ronni E. Sahl; Edmar Zanoteli; Michael W. Lawlor; Michael Wierer; Pieter Mestdagh; Jo Vandesompele; Julien Ochala; Morten Hostrup; Wim Derave; Atul S. Deshmukh
Remodeling of skeletal muscle myosin metabolic states in hibernating mammals
ELIFE
IF0
2024-05-163
OA
Lewis, Christopher T. A.; Melhedegaard, Elise G.; Ognjanovic, Marija M.; Olsen, Mathilde S.; Laitila, Jenni; Seaborne, Robert A. E.; Gronset, Magnus; Zhang, Changxin; Iwamoto, Hiroyuki; Hessel, Anthony L.; Kuehn, Michel N.; Merino, Carla; Amigo, Nuria; Frobert, Ole; Giroud, Sylvain; Staples, James F.; Goropashnaya, Anna, V; Fedorov, Vadim B.; Barnes, Brian; Toien, Oivind; Drew, Kelly; Sprenger, Ryan J.; Ochala, Julien
DNA methylation across the genome in aged human skeletal muscle tissue and muscle-derived cells: the role of HOX genes and physical activity
SCIENTIFIC REPORTS
IF3.9
2020-09-2181
OAAI
Turner, D. C.; Gorski, P. P.; Maasar, M. F.; Seaborne, R. A.; Baumert, P.; Brown, A. D.; Kitchen, M. O.; Erskine, R. M.; Dos-Remedios, I.; Voisin, S.; Eynon, N.; Sultanov, R. I.; Borisov, O. V.; Larin, A. K.; Semenova, E. A.; Popov, D. V.; Generozov, E. V.; Stewart, C. E.; Drust, B.; Owens, D. J.; Ahmetov, I. I.; Sharples, A. P.

研究方向

暂未获取到该数据
A
Adam P. Sharples
H 指数:36论文数:118被引数:3,687
J
Julien Ochala
H 指数:33论文数:181被引数:4,755
C
Claire E. Stewart
H 指数:50论文数:218被引数:8,506
A
Anthony L. Hessel
H 指数:14论文数:69被引数:650
D
Daniel C. Turner
H 指数:17论文数:51被引数:944
J
Jenni Laitila
H 指数:12论文数:61被引数:648
S
Sam O. Shepherd
H 指数:32论文数:130被引数:3,255
C
Christopher T. A. Lewis
H 指数:7论文数:34被引数:149
E
Elise G. Melhedegaard
H 指数:4论文数:22被引数:38
J
James P. Morton
H 指数:61论文数:325被引数:1.3万