Alain Laederach - Publications, H-index & Citations

Alain Laederach

University of North Carolina

41H指数

186论文数

5.7K被引数

收录论文 67

发表时间

The RNA binding protein ZFP36L2 displays tissue-selective mRNA targeting in mice RNA结合蛋白ZFP36L2在小鼠中表现出组织选择性mRNA靶向作用

RNA Biology

IF3.4

2026-06-21

OAAI

George Stephen Stephenson; Dalia Fleifel; Jeanette Gowen Cook; Alain Laederach; Silvia Beatriz Vieira Ramos

RNA Structural Ensemble Determinants of -1 Programmed Ribosomal Frameshifting Efficiency Across Coronavirus Evolution 冠状病毒进化过程中-1程序化核糖体移框效率的RNA结构群体决定因素

Journal of Molecular Biology

IF4.5

2025-10-28

OAAI

Scott R. Allen; Tamar Schlick; Alain Laederach

Visualizing RNA structure ensembles by singlemolecule correlated chemical probing 通过单分子相关化学探测可视化RNA结构集合

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2024-10-01

PREAI

Arney, J. Winston; Laederach, Alain; Weeks, Kevin M.

Abolished frameshifting for predicted structure-stabilizing SARS-CoV-2 mutants: implications to alternative conformations and their statistical structural analyses 废除了预测的结构稳定SARS-CoV-2突变体的移码: 对替代构象及其统计结构分析的影响

RNA

IF5

2024-07-31

OAAI

Dey, Abhishek; Yan, Shuting; Schlick, Tamar; Laederach, Alain

Orb2 enables rare-codon-enriched mRNA expression during Drosophila neuron differentiation Orb2在果蝇神经元分化过程中实现稀有密码子富集的mRNA表达

NATURE COMMUNICATIONS

IF15.7

2024-06-20

OAAI

Stewart, Rebeccah K.; Nguyen, Patrick; Laederach, Alain; Volkan, Pelin C.; Sawyer, Jessica K.; Fox, Donald T.

Colocalization analysis of 3′ UTR alternative polyadenylation quantitative trait loci reveals novel mechanisms underlying associations with lung function 3'utr替代多聚腺苷酸化数量性状基因座的共定位分析揭示了与肺功能相关的新机制

HUMAN MOLECULAR GENETICS

IF3.2

2024-04-03

PREAI

Saferali, Aabida; Kim, Wonji; Xu, Zhonghui; Chase, Robert P.; Cho, Michael H.; Laederach, Alain; Castaldi, Peter J.; Hersh, Craig P.

Coordinated expression of replication-dependent histone genes from multiple loci promotes histone homeostasis in Drosophila

MOLECULAR BIOLOGY OF THE CELL

IF2.7

2023-11-01

OAAI

Chaubal, Ashlesha; Waldern, Justin M.; Taylor, Colin; Laederach, Alain; Marzluff, William F.; Duronio, Robert J.

Structural analysis of MALAT1 long noncoding RNA in cells and in evolution MALAT1长链非编码RNA在细胞和进化中的结构分析

RNA

IF5

2023-02-15

OAAI

Monroy-Eklund, Anais; Taylor, Colin; Weidmann, Chase A.; Burch, Christina; Laederach, Alain

Global 5′-UTR RNA structure regulates translation of a SERPINA1 mRNA 全局5 ′-UTR RNA结构调节SERPINA1 mRNA的翻译

NUCLEIC ACIDS RESEARCH

IF13.1

2022-09-15

OAAI

Grayeski, Philip J.; Weidmann, Chase A.; Kumar, Jayashree; Lackey, Lela; Mustoe, Anthony M.; Busan, Steven; Laederach, Alain; Weeks, Kevin M.

Rotavirus RNA chaperone mediates global transcriptome-wide increase in RNA backbone flexibility 轮状病毒RNA伴侣介导RNA骨架灵活性的全球转录组范围的增加

NUCLEIC ACIDS RESEARCH

IF13.1

2022-09-05

OAAI

Coria, Aaztli; Wienecke, Anastacia; Knight, Michael L.; Desiro, Daniel; Laederach, Alain; Borodavka, Alexander

Quantitative prediction of variant effects on alternative splicing in MAPT using endogenous pre-messenger RNA structure probing

ELIFE

IF0

2022-06-13

OAAI

Kumar, Jayashree; Lackey, Lela; Waldern, Justin M.; Dey, Abhishek; Mustoe, Anthony M.; Weeks, Kevin M.; Mathews, David H.; Laederach, Alain; Staley, Jonathan P.

Distinct responses to rare codons in select Drosophila tissues 在选定的果蝇组织中对稀有密码子的不同反应

ELIFE

IF0

2022-05-06

OAAI

Allen, Scott R.; Stewart, Rebeccah K.; Rogers, Michael; Ruiz, Ivan Jimenez; Cohen, Erez; Laederach, Alain; Counter, Christopher M.; Sawyer, Jessica K.; Fox, Donald T.

Sequence and tissue targeting specificity of ZFP36L2 reveals Elavl2 as a novel target with co-regulation potential ZFP36L2的序列和组织靶向特异性揭示Elavl2作为具有共调节潜力的新靶标

NUCLEIC ACIDS RESEARCH

IF13.1

2022-04-05

OAAI

Redmon, Ian C.; Ardizzone, Matthew; Hekimoglu, Hilal; Hatfield, Breanne M.; Waldern, Justin M.; Dey, Abhishek; Montgomery, Stephanie A.; Laederach, Alain; Ramos, Silvia B., V

A novel algorithm for ranking RNA structure candidates 一种新的RNA结构候选排序算法

BIOPHYSICAL JOURNAL

IF3.1

2022-01-01

OAAI

Wienecke, Anastacia; Laederach, Alain

In vivo architecture of the telomerase RNA catalytic core in Trypanosoma brucei 布氏锥虫端粒酶RNA催化核心的体内结构

NUCLEIC ACIDS RESEARCH

IF13.1

2021-11-24

OAAI

Dey, Abhishek; Monroy-Eklund, Anais; Klotz, Kaitlin; Saha, Arpita; Davis, Justin; Li, Bibo; Laederach, Alain; Chakrabarti, Kausik

Disease-associated human genetic variation through the lens of precursor and mature RNA structure 通过前体和成熟RNA结构的晶状体与疾病相关的人类遗传变异

HUMAN GENETICS

IF3.6

2021-11-06

OAAI

Waldern, Justin M.; Kumar, Jayashree; Laederach, Alain

Cigarette smoking-associated isoform switching and 3′ UTR lengthening via alternative polyadenylation 吸烟相关的同工型转换和通过替代聚腺苷酸化的3'utr延长

GENOMICS

IF3

2021-11-01

OAAI

Xu, Zhonghui; Platig, John; Lee, Sool; Boueiz, Adel; Chase, Rob; Jain, Dhawal; Gregory, Andrew; Suryadevara, Rahul; Berman, Seth; Bowler, Russell; Hersh, Craig P.; Laederach, Alain; Castaldi, Peter J.

To Knot or Not to Knot: Multiple Conformations of the SARS-CoV-2 Frameshifting RNA Element 结或不结: SARS-CoV-2移码RNA元件的多种构象

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2021-07-20

OAAI

Schlick, Tamar; Zhu, Qiyao; Dey, Abhishek; Jain, Swati; Yan, Shuting; Laederach, Alain

Using SHAPE-MaP To Model RNA Secondary Structure and Identify 3′UTR Variation in Chikungunya Virus

JOURNAL OF VIROLOGY

IF3.8

2020-11-23

OAAI

Madden, Emily A.; Plante, Kenneth S.; Morrison, Clayton R.; Kutchko, Katrina M.; Sanders, Wes; Long, Kristin M.; Taft-Benz, Sharon; Cisneros, Marta C. Cruz; White, Ashlyn Morgan; Sarkar, Sanjay; Reynolds, Grace; Vincent, Heather A.; Laederach, Alain; Moorman, Nathanial J.; Heise, Mark T.

The Effects of Rare SERPINA1 Variants on Lung Function and Emphysema in SPIROMICS

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IF19.4

2020-03-01

OAAI

Ortega, Victor E.; Li, Xingnan; O'Neal, Wanda K.; Lackey, Lela; Ampleford, Elizabeth; Hawkins, Gregory A.; Grayeski, Philip J.; Laederach, Alain; Barjaktarevic, Igor; Barr, R. Graham; Cooper, Christopher; Couper, David; Han, MeiLan K.; Kanner, Richard E.; Kleerup, Eric C.; Martinez, Fernando J.; Paine, Robert, III; Peters, Stephen P.; Pirozzi, Cheryl; Rennard, Stephen, I; Woodruff, Prescott G.; Hoffman, Eric A.; Meyers, Deborah A.; Bleecker, Eugene R.

研究方向