Karl L. Magleby - Publications, H-index & Citations

Karl L. Magleby

university of miami

52H指数

135论文数

1.0W被引数

收录论文 55

发表时间

Case Report: Targeted treatment by fluoxetine/norfluoxetine of a KCNC2 variant causing developmental and epileptic encephalopathy 病例报告：使用氟西汀/去甲氟西汀针对导致发育性癫痫性脑病的KCNC2变异进行靶向治疗

FRONTIERS IN PHARMACOLOGY

IF4.8

2025-01-15

OAAI

Li, Ping; Butler, Alice; Zhou, Yu; Magleby, Karl L.; Gurnett, Christina A.; Salkoff, Lawrence

BK channels of five different subunit combinations underlie the de novo KCNMA1 G375R channelopathy

JOURNAL OF GENERAL PHYSIOLOGY

IF2.9

2023-03-30

OAAI

Geng, Yanyan; Li, Ping; Butler, Alice; Wang, Bill; Salkoff, Lawrence; Magleby, Karl L. L.

An allosteric modulator activates BK channels by perturbing coupling between Ca2+ binding and pore opening

NATURE COMMUNICATIONS

IF15.7

2022-11-09

OAAI

Zhang, Guohui; Xu, Xianjin; Jia, Zhiguang; Geng, Yanyan; Liang, Hongwu; Shi, Jingyi; Marras, Martina; Abella, Carlota; Magleby, Karl L.; Silva, Jonathan R.; Chen, Jianhan; Zou, Xiaoqin; Cui, Jianmin

Coupling of Ca2+ and voltage activation in BK channels through the αB helix/voltage sensor interface 通过 α b螺旋/电压传感器接口在BK通道中耦合Ca2和电压激活

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-06-08

OAAI

Geng, Yanyan; Deng, Zengqin; Zhang, Guohui; Budelli, Gonzalo; Butler, Alice; Yuan, Peng; Cui, Jianmin; Salkoff, Lawrence; Magleby, Karl L.

Voltage Dependent Gating of BK Channels - Where is the Spring?

BIOPHYSICAL JOURNAL

IF3.1

2019-02-01

OAAI

Magleby, Karl L.; Geng, Yanyan

Alpha-B Helix of the RCK1 Domain is a Shared Structural Element for Both Voltage and Calcium Activation of BK Channels

BIOPHYSICAL JOURNAL

IF3.1

2018-02-01

OAAI

Geng, Yanyan; Deng, Zengqin; Zhang, Guohui; Butler, Alice; Cui, Jianmin; Yuan, Peng; Salkoff, Lawrence; Magleby, Karl L.

A genetic variant of the sperm-specific SLO3 K+ channel has altered pH and Ca2+ sensitivities

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2017-05-01

OAAI

Geng, Yanyan; Ferreira, Juan J.; Dzikunu, Victor; Butler, Alice; Lybaert, Pascale; Yuan, Peng; Magleby, Karl L.; Salkoff, Lawrence; Santi, Celia M.

Deletion of cytosolic gating ring decreases gate and voltage sensor coupling in BK channels

JOURNAL OF GENERAL PHYSIOLOGY

IF2.9

2017-02-14

OAAI

Zhang, Guohui; Geng, Yanyan; Jin, Yakang; Shi, Jingyi; McFarland, Kelli; Magleby, Karl L.; Salkoff, Lawrence; Cui, Jianmin

Alpha-B Helix of RCK1 is a Major Transduction Pathway for Ca2+ Activation of BK Channels

BIOPHYSICAL JOURNAL

IF3.1

2017-02-01

OAAI

Geng, Yanyan; Deng, Zengqin; Budelli, Gonzalo; Butler, Alice Butler; Cui, Jianmin; Yuan, Peng; Salkoff, Lawrence; Magleby, Karl

STRUCTURAL BIOLOGY Ion-channel mechanisms revealed

NATURE

IF48.5

2016-12-14

OAAI

Magleby, Karl L.

Deletion of Cytoplasmic Gating Ring Alters Voltage Dependent Activation of BK Channels

BIOPHYSICAL JOURNAL

IF3.1

2016-02-01

OAAI

Zhang, Guohui; Geng, Yanyan; Shi, Jingyi; McFarland, Kelli; Magleby, Karl L.; Salkoff, Lawrence; Cui, Jianmin

Modal gating of endplate acetylcholine receptors: A proposed mechanism

JOURNAL OF GENERAL PHYSIOLOGY

IF2.9

2015-11-30

OAAI

Geng, Yanyan; Magleby, Karl L.

Single-channel kinetics of BK (Slo1) channels

FRONTIERS IN PHYSIOLOGY

IF3.4

2015-01-21

OAAI

Geng, Yanyan; Magleby, Karl L.

Baseline Properties of Slo1 K+ (BK) Channels Without the Gating Ring

BIOPHYSICAL JOURNAL

IF3.1

2014-01-01

OAAI

Geng, Yanyan; Budelli, Gonzalo; Butler, Alice; Santi, Celia; Ferreira, Juan; Salkoff, Lawrence; Magleby, Karl L.

Properties of Slo1 K+ channels with and without the gating ring

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2013-09-25

OAAI

Budelli, Gonzalo; Geng, Yanyan; Butler, Alice; Magleby, Karl L.; Salkoff, Lawrence

Exponential Sum-Fitting of Dwell-Time Distributions without Specifying Starting Parameters

BIOPHYSICAL JOURNAL

IF3.1

2013-06-01

OAAI

Landowne, David; Yuan, Bin; Magleby, Karl L.

Lack of negative slope in I-V plots for BK channels at positive potentials in the absence of intracellular blockers

JOURNAL OF GENERAL PHYSIOLOGY

IF2.9

2013-03-25

OAAI

Geng, Yanyan; Wang, Xiaoyu; Magleby, Karl L.

Voltage- and Ca2+-Activation of BK Channels Studied with Highly Constrained Allosteric Gating Mechanisms

BIOPHYSICAL JOURNAL

IF3.1

2012-01-01

PREAI

Chen, Ren-Shiang; Geng, Yanyan; Magleby, Karl L.

Short Isoforms of the Cold Receptor TRPM8 Inhibit Channel Gating by Mimicking Heat Action Rather than Chemical Inhibitors

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2012-01-01

OAAI

Fernandez, Jose A.; Skryma, Roman; Bidaux, Gabriel; Magleby, Karl L.; Scholfield, C. Norman; McGeown, J. Graham; Prevarskaya, Natalia; Zholos, Alexander V.

Contributions of the Inner Cavity to the Resistance of High Conductance K plus Channels Determined with a Two-Resistor Model

BIOPHYSICAL JOURNAL

IF3.1

2012-01-01

OAAI

Geng, Yanyan; Magleby, Karl L.

研究方向