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G

Giulia Biffi

University of Cambridge
H指数:22
被引数:1.4万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Multi-stromal organoid co-culture modelling reveals epithelial–fibroblast heterogeneity in pancreatic cancer and pancreatitis

多基质类器官共培养建模揭示胰腺癌和胰腺炎中上皮细胞-成纤维细胞的异质性

Nature Cell Biology
IF19.1
2026-09-020
OA
Wenlong Li; Muntadher Jihad; Eloise G. Lloyd; Marta Zaccaria; Gianluca Mucciolo; Gideon Nsubuga; Alwin Koonan-Lonappan; Joaquín Araos Henríquez; Priscilla S. W. Cheng; Sneha Harish; Sally Mills; Paul M. Johnson; Weike Luo; Alejandro Alonso Montero; Rebecca Brais; Alex Deamer; Ania M. Piskorz; Julia Jones; Jodi L. Miller; Bristi Basu; Paul D. W. Kirk; Mireia Vallespinos; Giulia Biffi
WEE1 inhibitors synergise with mRNA translation defects via activation of the kinase GCN2

WEE1抑制剂通过激活激酶GCN2与mRNA翻译缺陷产生协同作用

Nature Communications
IF15.7
2025-10-090
OAAI
Jordan C. J. Wilson; JiaYi Zhu; Vanesa Vinciauskaite; Eloise G. Lloyd; Simon Lam; Alexandra Hart; Chen Gang Goh; Fadia Bou-Dagher; Hlib Razumkov; Lena Kobel; Zacharias Kontarakis; John Fielden; Moritz F. Schlapansky; Joanna I. Loizou; Andreas Villunger; Jacob E. Corn; Giulia Biffi; Glenn R. Masson; Stefan J. Marciniak; Aldo S. Bader; Stephen P. Jackson
Differential activity of MAPK signalling defines fibroblast subtypes in pancreatic cancer

MAPK信号传导的差异活性定义了胰腺癌中的成纤维细胞亚型

NATURE COMMUNICATIONS
IF15.7
2024-12-030
OAAI
Veghini, Lisa; Pasini, Davide; Fang, Rui; Delfino, Pietro; Filippini, Dea; Neander, Christian; Vicentini, Caterina; Fiorini, Elena; Lupo, Francesca; D'Agosto, Sabrina L.; Carbone, Carmine; Agostini, Antonio; Piro, Geny; Rosa, Diego; Bevere, Michele; Markus, Peter; Behrens, Diana; Luchini, Claudio; Lawlor, Rita T.; Scarpa, Aldo; Biffi, Giulia; Cheung, Phyllis F.; Siveke, Jens T.; Corbo, Vincenzo
Scribble Deficiency Promotes Pancreatic Ductal Adenocarcinoma Development and Metastasis
CANCER RESEARCH
IF16.6
2024-07-220
PRE
Bermejo-Rodriguez, Camino; Araos Henriquez, Joaquin; Caligiuri, Giuseppina; Pinto Teles, Sara; Park, Youngkyu; Evans, Anthony; Barrera, Lawrence N.; Neesse, Albrecht; Gruetzmann, Robert; Aust, Daniela; Ruemmele, Petra; Knoesel, Thomas; Narita, Masako; Narita, Masashi; Campbell, Fiona; Oehlund, Daniel; Pilarsky, Christian; Dow, Lukas E.; Humbert, Patrick O.; Biffi, Giulia; Tuveson, David A.; Perez-Mancera, Pedro A.
Single-cell transcriptomic analysis of human pleura reveals stromal heterogeneity and informs in vitro models of mesothelioma
EUROPEAN RESPIRATORY JOURNAL
IF21
2024-01-110
OAAI
Obacz, Joanna; Valer, Jose Antonio; Nibhani, Reshma; Adams, Taylor S.; Schupp, Jonas C.; Veale, Niki; Lewis-Wade, Amanah; Flint, Jasper; Hogan, John; Aresu, Giuseppe; Coonar, Aman S.; Peryt, Adam; Biffi, Giulia; Kaminski, Naftali; Francies, Hayley; Rassl, Doris M.; Garnett, Mathew J.; Rintoul, Robert C.; Marciniak, Stefan J.
Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer
CLINICAL CANCER RESEARCH
IF10.2
2021-01-25188
OA
Steele, Nina G.; Biffi, Giulia; Kemp, Samantha B.; Zhang, Yaqing; Drouillard, Donovan; Syu, LiJyun; Hao, Yuan; Oni, Tobiloba E.; Brosnan, Erin; Elyada, Ela; Doshi, Abhishek; Hansma, Christa; Espinoza, Carlos; Abbas, Ahmed; The, Stephanie; Irizarry-Negron, Valerie; Halbrook, Christopher J.; Franks, Nicole E.; Hoffman, Megan T.; Brown, Kristee; Carpenter, Eileen S.; Nwosu, Zeribe C.; Johnson, Craig; Lima, Fatima; Anderson, Michelle A.; Park, Youngkyu; Crawford, Howard C.; Lyssiotis, Costas A.; Frankel, Timothy L.; Rao, Arvind; Bednar, Filip; Dlugosz, Andrzej A.; Preall, Jonathan B.; Tuveson, David A.; Allen, Benjamin L.; di Magliano, Marina Pasca
Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma
ELIFE
IF0
2020-07-1065
OA
Lau, Allison N.; Li, Zhaoqi; Danai, Laura, V; Westermark, Anna M.; Darnell, Alicia M.; Ferreira, Raphael; Gocheva, Vasilena; Sivanand, Sharanya; Lien, Evan C.; Sapp, Kiera M.; Mayers, Jared R.; Biffi, Giulia; Chin, Christopher R.; Davidson, Shawn M.; Tuveson, David A.; Jacks, Tyler; Matheson, Nicholas J.; Yilmaz, Omer; Vander Heiden, Matthew G.
SOAT1 promotes mevalonate pathway dependency in pancreatic cancer

SOAT1促进胰腺癌中甲羟戊酸途径的依赖性

JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2020-07-0782
OAAI
Oni, Tobiloba E.; Biffi, Giulia; Baker, Lindsey A.; Hao, Yuan; Tonelli, Claudia; Somerville, Tim D. D.; Deschenes, Astrid; Belleau, Pascal; Hwang, Chang-il; Sanchez-Rivera, Francisco J.; Cox, Hilary; Brosnan, Erin; Doshi, Abhishek; Lumia, Rebecca P.; Khaledi, Kimia; Park, Youngkyu; Trotman, Lloyd C.; Lowe, Scott W.; Krasnitz, Alexander; Vakoc, Christopher R.; Tuveson, David A.
Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts

胰腺导管腺癌的跨物种单细胞分析揭示了抗原呈递癌症相关的成纤维细胞

CANCER DISCOVERY
IF33.3
2019-08-011.3K
OAAI
Elyada, Ela; Bolisetty, Mohan; Laise, Pasquale; Flynn, William F.; Courtois, Elise T.; Burkhart, Richard A.; Teinor, Jonathan A.; Belleau, Pascal; Biffi, Giulia; Lucito, Matthew S.; Sivajothi, Santhosh; Armstrong, Todd D.; Engle, Dannielle D.; Yu, Kenneth H.; Hao, Yuan; Wolfgang, Christopher L.; Park, Youngkyu; Preall, Jonathan; Jaffee, Elizabeth M.; Califano, Andrea; Robson, Paul; Tuveson, David A.

研究方向

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D
David A. Tuveson
H 指数:113论文数:897被引数:8.6万
S
Shankar Balasubramanian
H 指数:118论文数:522被引数:5.7万
Y
Youngkyu Park
H 指数:45论文数:335被引数:1.5万
E
Ela Elyada
H 指数:15论文数:99被引数:1.0万
H
Hao Yuan
H 指数:31论文数:87被引数:8,837
D
Daniel Öhlund
H 指数:25论文数:216被引数:8,276
E
Eloise G. Lloyd
H 指数:4论文数:31被引数:193
D
David Tannahill
H 指数:44论文数:100被引数:1.2万
M
Marco Di Antonio
H 指数:40论文数:179被引数:9,126
J
Jonathan Preall
H 指数:22论文数:132被引数:1.4万