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T

Tadhg P. Begley

Texas A&M University System

66H指数
306论文数
1.4W被引数
收录论文 115
发表时间
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Insights into the initial steps of the thiamin pyrimidine synthase (ThiC)-catalyzed reaction through EPR spectroscopic characterization of radical intermediates通过EPR光谱学表征自由基中间体，对硫胺素嘧啶合成酶(ThiC)催化反应的初始步骤的见解
errChem. Sci.
IF7.4
err2025-11-19
err0
errOAAI
errMelissa Bollmeyer; Vishav Sharma; Dmytro Fedoseyenko; Yumeng Cao; Guodong Rao; Dean J Tantillo; Tadhg P. Begley; R. David Britt
err分享
err收藏
Vitamin B2 Catabolism: Nature's Route from Riboflavin to Acetoacetate and Pyruvate
errACS CENTRAL SCIENCE
IF10.4
err2025-11-01
err1
PREAI
errSinha, Sreyashi; Jian, Xiaohong; Adak, Sanjoy; Naseem, Saad; Steiner, Jessica L.; Fedoseyenko, Dmytro; Thiagarayaselvam, Aarthy; Begley, Tadhg P.
err分享
err收藏
Phosphomethylpyrimidine Synthase (ThiC): Trapping of Five Intermediates Provides Mechanistic Insights on a Complex Radical Cascade Reaction in Thiamin Biosynthesis
errACS CENTRAL SCIENCE
IF10.4
err2024-05-13
err1
errOAAI
errSharma, Vishav; Fedoseyenko, Dmytro; Joshi, Sumedh; Abdelwahed, Sameh; Begley, Tadhg P.
err分享
err收藏
Characterization of a bacterial vitamin B2 catabolic pathway
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-03-01
err0
errOAAI
errSinha, Sreyashi; Naseem, Saad; Adak, Sanjoy; Jian, Xiaohong; Steiner, Jessica; Selvam, Aarthy Thiagaraya; Fedoseyenko, Dymtro; Begley, Tadhg
err分享
err收藏
Menaquinone Biosynthesis: Regioselectivity of Prenylation and Methylation in the final steps of aminofutalosine pathway
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-03-01
err0
errOAAI
errHazra, Sohan; Begley, Tadhg
err分享
err收藏
Phosphomethylpyrimidine synthase (ThiC): A Radical Dance in bacterial thiamin biosynthesis
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-03-01
err0
errOAAI
errSharma, Vishav; Fedoseyenko, Dymtro; Joshi, Sumedh; Abdelwahed, Sameh; Begley, Tadhg
err分享
err收藏
Alkylcysteine Sulfoxide C-S Monooxygenase Uses a Flavin-Dependent Pummerer Rearrangement
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2023-05-25
err7
errOAAI
errHazra, Sohan; Begley, Tadhg P.
err分享
err收藏
Oxidative Dearomatization of PLP in Thiamin Pyrimidine Biosynthesis in Candida albicans
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2023-02-20
err2
errOAAI
errMondal, Anushree; Lai, Rung-Yi; Fedoseyenko, Dmytro; Giri, Nitai; Begley, Tadhg P.
err分享
err收藏
Mechanistic Studies on the Single-Turnover Yeast Thiamin Pyrimidine Synthase: Characterization of the Inactive Enzyme
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2022-06-08
err2
PREAI
errLai, Rung-Yi; Mondal, Anushree; Fedoseyenko, Dmytro; Begley, Tadhg P.
err分享
err收藏
Trapping and structural characterisation of a covalent intermediate in vitamin B6 biosynthesis catalysed by the Pdx1 PLP synthase
errRSC CHEMICAL BIOLOGY
IF3.1
err2022-01-01
err3
errOAAI
errRodrigues, Matthew J.; Giri, Nitai; Royant, Antoine; Zhang, Yang; Bolton, Rachel; Evans, Gwyndaf; Ealick, Steve E.; Begley, Tadhg; Tews, Ivo
err分享
err收藏
Radiosynthesis of 5-[18F]Fluoro-1,2,3-triazoles through Aqueous Iodine-[18F]Fluorine Exchange Reaction
errMOLECULES
IF4.6
err2021-09-11
err4
errOAAI
errZhang, Xiang; Basuli, Falguni; Abdelwahed, Sameh; Begley, Tadhg; Swenson, Rolf
err分享
err收藏
Structural basis for antibiotic action of the B1 antivitamin 2′-methoxy-thiamine
errNATURE CHEMICAL BIOLOGY
IF13.7
err2020-08-24
err17
errOAAI
errRabe von Pappenheim, Fabian; Aldeghi, Matteo; Shome, Brateen; Begley, Tadhg; de Groot, Bert L.; Tittmann, Kai
err分享
err收藏
Radical SAM Enzyme HydE Generates Adenosylated Fe(I) Intermediates En Route to the [FeFe]-Hydrogenase Catalytic H-Cluster
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2020-05-21
err43
errOAAI
errTao, Lizhi; Pattenaude, Scott A.; Joshi, Sumedh; Begley, Tadhg P.; Rauchfuss, Thomas B.; Britt, R. David
err分享
err收藏
Mechanistic Studies on CysS - A Vitamin B12-Dependent Radical SAM Methyltransferase Involved in the Biosynthesis of the tert-Butyl Group of Cystobactamid
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2020-05-06
err34
PREAI
errWang, Yuanyou; Begley, Tadhg P.
err分享
err收藏
Trapping and Electron Paramagnetic Resonance Characterization of the 5′dAdo• Radical in a Radical S-Adenosyl Methionine Enzyme Reaction with a Non-Native Substrate
errACS CENTRAL SCIENCE
IF10.4
err2019-09-25
err57
errOAAI
errSayler, Richard I.; Stich, Troy A.; Joshi, Sumedh; Cooper, Nicole; Shaw, Jared T.; Begley, Tadhg P.; Tantillo, Dean J.; Britt, R. David
err分享
err收藏
Antibacterial Strategy against H. pylori: Inhibition of the Radical SAM Enzyme MqnE in Menaquinone Biosynthesis
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2019-02-15
err14
errOAAI
errJoshi, Sumedh; Fedoseyenko, Dmytro; Mahanta, Nilkamal; Ducati, Rodrigo G.; Feng, Mu; Schramm, Vern L.; Begley, Tadhg P.
err分享
err收藏
Novel enzymology in futalosine-dependent menaquinone biosynthesis
errCURRENT OPINION IN CHEMICAL BIOLOGY
IF6.1
err2018-12-01
err40
errOAAI
errJoshi, Sumedh; Fedoseyenko, Dmytro; Mahanta, Nilkamal; Manion, Hannah; Naseem, Saad; Dairi, Tohru; Begley, Tadhg P.
err分享
err收藏
An Aminoimidazole Radical Intermediate in the Anaerobic Biosynthesis of the 5,6-Dimethylbenzimidazole Ligand to Vitamin B12
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2018-09-13
err19
errOAAI
errGagnon, Derek M.; Stich, Troy A.; Mehta, Angad P.; Abdelwahed, Sameh H.; Begley, Tadhg P.; Britt, R. David
err分享
err收藏
Mechanistic Studies on Tryptophan Lyase (NosL): Identification of Cyanide as a Reaction Product
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2018-01-02
err29
errOAAI
errBhandari, Dhananjay M.; Fedoseyenko, Dmytro; Begley, Tadhg P.
err分享
err收藏
Globally Important Haptophyte Algae Use Exogenous Pyrimidine Compounds More Efficiently than Thiamin
errMBIO
IF4.7
err2017-11-08
err35
errOAAI
errGutowska, Magdalena A.; Shome, Brateen; Sudek, Sebastian; McRose, Darcy L.; Hamilton, Maria; Giovannoni, Stephen J.; Begley, Tadhg P.; Worden, Alexandra Z.
err分享
err收藏

研究方向

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合作学者
合作期刊
A
Aziz Sancar
H 指数: 122 · 论文数: 595
P
Pieter C. Dorrestein
H 指数: 122 · 论文数: 872
C
Clifton E. Barry
H 指数: 113 · 论文数: 448
张扬 封面图
张扬 (Yang Zhang)
H 指数: 112 · 论文数: 1.6K
N
Neil L. Kelleher
H 指数: 106 · 论文数: 714
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