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Adam Frost

university of california
H指数:48
被引数:1.1万

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ESCRT-III assembles around mis-segregated DNA to protect genome stability

ESCRT-III在错误分离的DNA周围组装以保护基因组稳定性

NATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
2026-07-150
OAAI
James Glover; Nathaniel Talledge; John McCullough; Akram Alian; Jessica B. A. Sadler; Sahil Kamboj; Nathaniel W. M. Dempsey; Thomas G. Laughlin; Henry C. Nguyen; Dawn M. Wenzel; Matthew S. Lalonde; Elliott L. Paine; Barbie Ganser-Pornillos; Leandro N. Ventimiglia; Dollie LaJoie; Janet H. Iwasa; Christopher P. Arthur; D. John Lee; Frank R. Moss; Meera Venkatesh; Lydia M. Arnold; Jarrod S. Johnson; Katharine S. Ullman; Adam Frost; Wesley I. Sundquist; Juan Martin-Serrano
Allosteric disordering of eIF2B regulates the integrated stress response

eIF2B的别构失序调控整合应激反应

Nature Chemical Biology
IF13.7
2026-06-290
OAAI
Udit Dalwadi; Advait Subramanian; Aniliese Deal; Julia E. Conrad; Tamara Nadjsombati; Meera Venkatesh; Morgane Boone; Pascal F. Egea; Lingjie He; Nimit Jain; D. John Lee; Yuwei Liu; Lucas C. Reineke; Kazuki Saito; Nathaniel Talledge; Hannah Toutkoushian; Maxence Le Vasseur; Francesca Zappa; Raoul J. de Groot; Diego Acosta-Alvear; Christopher P. Arthur; Jodi Nunnari; Susan Marqusee; Rosalie E. Lawrence; Mauro Costa-Mattioli; James J. Crawford; Frank J. M. van Kuppeveld; Tristan I. Croll; Peter Walter; Adam Frost
Harnessing viral strategies to reverse cognitive dysfunction through the integrated stress response

利用病毒策略通过整合应激反应逆转认知功能障碍

Science
IF45.8
2026-04-020
PRE
Lucas C. Reineke; Ping Jun Zhu; Udit Dalwadi; Sean W. Dooling; Yuwei Liu; I-Ching Wang; Sara Young-Baird; James Okoh; Santosh Kumar Kuncha; Hongyi Zhou; Akshara Kannan; Hyekyung Park; Nicolas A. Debeaubien; Tristan Croll; D. John Lee; Christopher Arthur; Thomas E. Dever; Peter Walter; Jin Chen; Adam Frost; Mauro Costa-Mattioli
Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia

RLY-2608的发现和临床概念验证，这是一种一流的突变选择性变构PI3Kα 抑制剂，可使高胰岛素血症的抗肿瘤活性脱钩

CANCER DISCOVERY
IF33.3
2023-11-1314
OAAI
Varkaris, Andreas; Pazolli, Ermira; Gunaydin, Hakan; Wang, Qi; Pierce, Levi; Boezio, Alessandro A.; Bulku, Artemisa; Dipietro, Lucian; Fridrich, Cary; Frost, Adam; Giordanetto, Fabrizio; Hamilton, Erika P.; Harris, Katherine; Holliday, Michael; Hunter, Tamieka L.; Iskandar, Amanda; Ji, Yongli; Larivee, Alexandre; Larochelle, Jonathan R.; Lescarbeau, Andre; Llambi, Fabien; Lormil, Brenda; Mader, Mary M.; Mar, Brenton G.; Martin, Iain; Mclean, Thomas H.; Michelsen, Klaus; Pechersky, Yakov; Puente-Poushnejad, Erika; Raynor, Kevin; Rogala, Dipali; Samadani, Ramin; Schram, Alison M.; Shortsleeves, Kelley; Swaminathan, Sweta; Tajmir, Shahein; Tan, Gege; Tang, Yong; Valverde, Roberto; Wehrenberg, Bryan; Wilbur, Jeremy; Williams, Bret R.; Zeng, Hongtao; Zhang, Hanmo; Walters, W. Patrick; Wolf, Beni B.; Shaw, David E.; Bergstrom, Donald A.; Watters, James; Fraser, James S.; Fortin, Pascal D.; Kipp, D. Randal
A structural biology community assessment of AlphaFold2 applications

对AlphaFold2应用的结构生物学社区评估

NATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
2022-11-07259
OAAI
Akdel, Mehmet; Pires, Douglas E., V; Porta Pardo, Eduard; Janes, Jurgen; Zalevsky, Arthur O.; Meszaros, Balint; Bryant, Patrick; Good, Lydia L.; Laskowski, Roman A.; Pozzati, Gabriele; Shenoy, Aditi; Zhu, Wensi; Kundrotas, Petras; Serra, Victoria Ruiz; Rodrigues, Carlos H. M.; Dunham, Alistair S.; Burke, David; Borkakoti, Neera; Velankar, Sameer; Frost, Adam; Basquin, Jerome; Lindorff-Larsen, Kresten; Bateman, Alex; Kajava, Andrey, V; Valencia, Alfonso; Ovchinnikov, Sergey; Durairaj, Janani; Ascher, David B.; Thornton, Janet M.; Davey, Norman E.; Stein, Amelie; Elofsson, Arne; Croll, Tristan, I; Beltrao, Pedro

研究方向

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F
Frank R. Moss
H 指数:17论文数:49被引数:3,577
N
Nathaniel Talledge
H 指数:10论文数:24被引数:704
W
Wesley I. Sundquist
H 指数:87论文数:233被引数:2.7万
M
Morgane Boone
H 指数:11论文数:54被引数:1,736
H
Henry C. Nguyen
H 指数:23论文数:97被引数:4,624
M
Michael Schoof
H 指数:8论文数:24被引数:958
J
John McCullough
H 指数:23论文数:70被引数:3,307
P
Peter Walter
H 指数:118论文数:586被引数:6.5万
王
王兰
H 指数:30论文数:221被引数:3,005
M
Mary Munson
H 指数:34论文数:87被引数:4,558