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NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo Namoto, Kenji; Baader, Clara; Orsini, Vanessa; Landshammer, Alexandro; Breuer, Eva; Dinh, Kieu Trinh; Ungricht, Rosemarie; Pikiolek, Monika; Laurent, Stephane; Lu, Bo; Aebi, Alexandra; Nberger, Katharina Schoenberger; Vangrevelinghe, Eric; Evrova, Olivera; Sun, Tianliang; Annunziato, Stefano; Lachal, Julie; Redmond, Emily; Wang, Louis; Wetzel, Kristie; Capodieci, Paola; Turner, Jonathan; Schutzius, Gabi; Unterreiner, Vincent; Trunzer, Markus; Buschmann, Nicole; Behnke, Dirk; Machauer, Rainer; Scheufler, Clemens; Parker, Christian N.; Ferro, Magali; Grevot, Armelle; Beyerbach, Armin; Lu, Wei-Yu; Forbes, Stuart J.; Wagner, Jueurorgen; Bouwmeester, Tewis; Liu, Jun; Sohal, Bindi; Sahambi, Sukhdeep; Greenbaum, Linda E.; Lohmann, Felix; Hoppe, Philipp; Cong, Feng; Sailer, Andreas W.; Ruffner, Heinz; Glatthar, Ralf; Humar, Bostjan; Clavien, Pierre-Alain; Dill, Michael T.; George, Elizabeth; Maibaum, Jueurorgen; Liberali, Prisca; Tchorz, Jan S. 分享 收藏
Non-invasive candidate protein signature predicts hepatic venous pressure gradient reduction in cirrhotic patients after sustained virologic response 非侵入性候选蛋白签名预测持续病毒学应答后肝硬化患者肝静脉压力梯度降低 Richards, Shola M.; Guo, Fang; Zou, Heng; Nigsch, Florian; Baiges, Anna; Pachori, Alok; Zhang, Yiming; Lens, Sabela; Pitts, Rebecca; Finkel, Nancy; Loureiro, Joseph; Mongeon, Dale; Ma, Shenglin; Watkins, Mollie; Polus, Florine; Albillos, Agustin; Tellez, Luis; Martinez-Gonzalez, Javier; Banares, Rafael; Turon, Fanny; Ferrusquia-Acosta, Jose; Perez-Campuzano, Valeria; Magaz, Marta; Forns, Xavier; Badman, Michael; Sailer, Andreas W.; Ukomadu, Chinweike; Hernandez-Gea, Virginia; Garcia-Pagan, Juan Carlos 分享 收藏
ZNRF3 and RNF43 cooperate to safeguard metabolic liver zonation and hepatocyte proliferation ZNRF3和RNF43协同保护代谢肝分区和肝细胞增殖 Sun, Tianliang; Annunziato, Stefano; Bergling, Sebastian; Sheng, Caibin; Orsini, Vanessa; Forcella, Pascal; Pikiolek, Monika; Kancherla, Venkatesh; Holwerda, Sjoerd; Imanci, Dilek; Wu, Fabian; Meylan, Ludivine Challet; Puehringer, Lea F.; Waldt, Annick; Oertli, Mevion; Schuierer, Sven; Terracciano, Luigi M.; Reinker, Stefan; Ruffner, Heinz; Bouwmeester, Tewis; Sailer, Andreas W.; George, Elizabeth; Roma, Guglielmo; de Weck, Antoine; Piscuoglio, Salvatore; Lohmann, Felix; Naumann, Ulrike; Liberali, Prisca; Cong, Feng; Tchorz, Jan S. 分享 收藏
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Elevated oxysterol levels in human and mouse livers reflect nonalcoholic steatohepatitis Raselli, Tina; Hearn, Tom; Wyss, Annika; Atrott, Kirstin; Peter, Alain; Frey-Wagner, Isabelle; Spalinger, Marianne R.; Maggio, Ewerton M.; Sailer, Andreas W.; Schmitt, Johannes; Schreiner, Philipp; Mancsek, Anja; Mertens, Joachim; Scharl, Michael; Griffiths, William J.; Bueter, Marco; Geier, Andreas; Rogler, Gerhard; Wang, Yuqin; Misselwitz, Benjamin 分享 收藏
YAP, but Not RSPO-LGR4/5, Signaling in Biliary Epithelial Cells Promotes a Ductular Reaction in Response to Liver Injury Planas-Paz, Lara; Sun, Tianliang; Pikiolek, Monika; Cochran, Nadire R.; Bergling, Sebastian; Orsini, Vanessa; Yang, Zinger; Sigoillot, Frederic; Jetzer, Jasna; Syed, Maryam; Neri, Marilisa; Schuierer, Sven; Morelli, Lapo; Hoppe, Philipp S.; Schwarzer, Wibke; Cobos, Carlos M.; Alford, John L.; Zhang, Le; Cuttat, Rachel; Waldt, Annick; Carballido-Perrig, Nicole; Nigsch, Florian; Kinzel, Bernd; Nicholson, Thomas B.; Yang, Yi; Mao, Xiaohong; Terracciano, Luigi M.; Russ, Carsten; Reece-Hoyes, John S.; Keller, Caroline Gubser; Sailer, Andreas W.; Bouwmeester, Tewis; Greenbaum, Linda E.; Lugus, Jesse J.; Cong, Feng; McAllister, Gregory; Hoffman, Gregory R.; Roma, Guglielmo; Tchorz, Jan S. 分享 收藏
The EBI2-oxysterol axis promotes the development of intestinal lymphoid structures and colitis Wyss, Annika; Raselli, Tina; Perkins, Nathan; Ruiz, Florian; Schmelczer, Gerard; Klinke, Glynis; Moncsek, Anja; Roth, Rene; Spalinger, Marianne R.; Hering, Larissa; Atrott, Kirstin; Lang, Silvia; Frey-Wagner, Isabelle; Mertens, Joachim C.; Scharl, Michael; Sailer, Andreas W.; Pabst, Oliver; Hersberger, Martin; Pot, Caroline; Rogler, Gerhard; Misselwitz, Benjamin 分享 收藏
The Oxysterol Synthesising Enzyme CH25H Contributes to the Development of Intestinal Fibrosis Raselli, T.; Wyss, A.; Alvarado, M. N. Gonzalez; Weder, B.; Mamie, C.; Spalinger, M. R.; van Haaften, W. T.; Dijkstra, G.; Sailer, A. W.; Silva, P. H. Imenez; Wagner, C. A.; Tosevski, V.; Leibl, Sebastian; Scharl, M.; Rogler, G.; Hausmann, M.; Misselwitz, B. 分享 收藏
Genome-wide CRISPR screen for PARKIN regulators reveals transcriptional repression as a determinant of mitophagy Potting, Christoph; Crochemore, Christophe; Moretti, Francesca; Nigsch, Florian; Schmidt, Isabel; Manneville, Carole; Carbone, Walter; Knehr, Judith; DeJesus, Rowena; Lindeman, Alicia; Maher, Rob; Russ, Carsten; McAllister, Gregory; Reece-Hoyes, John S.; Hoffman, Gregory R.; Roma, Guglielmo; Mueller, Matthias; Sailer, Andreas W.; Helliwell, Stephen B. 分享 收藏
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An Activating Janus Kinase-3 Mutation Is Associated with Cytotoxic T Lymphocyte Antigen-4-Dependent Immune Dysregulation Syndrome Sic, Heiko; Speletas, Matthaios; Cornacchione, Vanessa; Seidl, Maximillian; Beibel, Martin; Linghu, Bolan; Yang, Fan; Sevdali, Eirini; Germenis, Anastasios E.; Oakeley, Edward J.; Vangrevelinghe, Eric; Sailer, Andreas W.; Traggiai, Elisabetta; Gram, Hermann; Eibel, Hermann 分享 收藏
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Mutations in MAPKBP1 Cause Juvenile or Late-Onset Cilia-Independent Nephronophthisis (vol 100, pg 323, 2017) Macia, Maxence S.; Halbritter, Jan; Delous, Marion; Bredrup, Cecilie; Gutter, Arthur; Filhol, Emilie; Mellgren, Anne E. C.; Leh, Sabine; Bizet, Albane; Braun, Daniela A.; Gee, Heon Y.; Silbermann, Flora; Henry, Charline; Krug, Pauline; Bole-Feysot, Christine; Nitschke, Patrick; Joly, Dominique; Nicoud, Philippe; Paget, Andre; Haugland, Heidi; Brackmann, Damien; Ahmet, Nayir; Sandford, Richard; Cengiz, Nurcan; Knappskog, Per M.; Boman, Helge; Linghu, Bolan; Yang, Fan; Oakeley, Edward J.; Saint Mezard, Pierre; Sailer, Andreas W.; Johansson, Stefan; Rodahl, Eyvind; Saunier, Sophie; Hildebrandt, Friedhelm; Benmerah, Alexandre 分享 收藏
Mutations in MAPKBP1 Cause Juvenile or Late-Onset Cilia-Independent Nephronophthisis Macia, Maxence S.; Halbritter, Jan; Delous, Marion; Bredrup, Cecilie; Gutter, Arthur; Filhol, Emilie; Mellgren, Anne E. C.; Leh, Sabine; Bizet, Albane; Braun, Daniela A.; Gee, Heon Y.; Sibermann, Flora; Henry, Charline; Krug, Pauline; Bole-Feysot, Christine; Nitschke, Patrick; Joly, Dominique; Nicoud, Philippe; Paget, Andre; Haugland, Heidi; Brackmann, Damien; Ahmet, Nayir; Sandford, Richard; Cengiz, Nurcan; Knappskog, Per M.; Boman, Helge; Linghu, Bolan; Yang, Fan; Oakeley, Edward J.; Saint Mezard, Pierre; Sailer, Andreas W.; Johansson, Stefan; Rodahl, Eyvind; Saunier, Sophie; Hildebrandt, Friedhelm; Benmerah, Alexandre 分享 收藏
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EBI2 Is Highly Expressed in Multiple Sclerosis Lesions and Promotes Early CNS Migration of Encephalitogenic CD4 T Cells Eb12在多发性硬化病变中高表达并促进致脑炎性CD4 T细胞的早期中枢神经系统迁移 Wanke, Florian; Moos, Sonja; Croxford, Andrew L.; Heinen, Andre P.; Graef, Stephanie; Kalt, Bettina; Tischner, Denise; Zhang, Juan; Christen, Isabelle; Bruttger, Julia; Yogev, Nir; Tang, Yilang; Zayoud, Morad; Israel, Nicole; Karram, Khalad; Reissig, Sonja; Lacher, Sonja M.; Reichhold, Christian; Mufazalov, Ilgiz A.; Ben-Nun, Avraham; Kuhlmann, Tanja; Wettschureck, Nina; Sailer, Andreas W.; Rajewsky, Klaus; Casola, Stefano; Waisman, Ari; Kurschus, Florian C. 分享 收藏
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TLR and RLR Signaling Are Reprogrammed in Opposite Directions after Detection of Viral Infection Hotz, Christian; Roetzer, Laurin C.; Huber, Thomas; Sailer, Andreas; Oberson, Anne; Treinies, Marina; Heidegger, Simon; Herbst, Tina; Endres, Stefan; Bourquin, Carole 分享 收藏
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