William A. Eaton - Publications, H-index & Citations

William A. Eaton

National Institutes of Health

85H指数

237论文数

2.4W被引数

收录论文 68

发表时间

Comparative Analysis of CRISPR-Cas9, lentiviral transduction, and base editing for sickle cell disease in a murine model CRISPR-Cas9、慢病毒转导和碱基编辑技术在镰状细胞病小鼠模型中的比较分析

Blood Advances

IF7.1

2025-10-30

OAAI

Henna Butt; Shruti Sathish; Evan London; Anh Le; Quan Li; Bjorg Gudmundsdottir; Duck-Yeon Lee; Emma V. Burke; Bradley P. Yates; David R. Liu; Matthew Hsieh; Alexis Leonard; William A. Eaton; Naoya Uchida; Francis J. Pierciey; Gregory A. Newby; John F. Tisdale; Selami Demirci

In vivo measurement of RBC survival in patients with sickle cell disease before or after hematopoietic stem cell transplantation

BLOOD ADVANCES

IF7.1

2024-04-09

OAAI

Leonard, Alexis K.; Furstenau, Dana; Inam, Zaina; Luckett, Christina; Chu, Rebecca; Demirci, Selami; Essawi, Khaled; Gudmundsdottir, Bjorg; Hinds, Malikiya; DiNicola, Julia; Li, Quan; Eaton, William A.; Cellmer, Troy; Wang, Xunde; Thein, Swee Lay; Macari, Elizabeth R.; VanNest, Sara; Hsieh, Matthew M.; Bonner, Melissa; Pierciey, Francis J.; Tisdale, John F.

Functional and multi-omics signatures of mitapivat efficacy upon activation of pyruvate kinase in red blood cells from patients with sickle cell disease

HAEMATOLOGICA

IF7.9

2024-03-07

OAAI

D'Alessandro, Angelo; Le, Kang; Lundt, Maureen; Li, Quan; Dunkelberger, Emily B.; Cellmer, Troy; Worth, Andrew J.; Patil, Spurthi; Huston, Chris; Grier, Abby; Dzieciatkowska, Monika; Stephenson, Daniel; Eaton, William A.; Thein, Swee Lay

A retrospective on statistical mechanical models for hemoglobin allostery

JOURNAL OF CHEMICAL PHYSICS

IF3.1

2022-11-08

OAAI

Eaton, William A.

Drug discovery by a basic research scientist

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2022-11-03

OAAI

Eaton, William A.

Phenotypic screening of the ReFRAME drug repurposing library to discover new drugs for treating sickle cell disease 重组药物再利用库的表型筛选发现治疗镰状细胞病的新药

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-09-26

OAAI

Metaferia, Belhu; Cellmer, Troy; Dunkelberger, Emily B.; Li, Quan; Henry, Eric R.; Hofrichter, James; Staton, Dwayne; Hsieh, Matthew M.; Conrey, Anna K.; Tisdale, John F.; Chatterjee, Arnab K.; Thein, Swee Lay; Eaton, William A.

Impact of hemoglobin biophysical studies on molecular pathogenesis and drug therapy for sickle cell disease

MOLECULAR ASPECTS OF MEDICINE

IF10.3

2022-04-01

OAAI

Eaton, William A.

MWC allosteric model explains unusual hemoglobin-oxygen binding curves from sickle cell drug binding

BIOPHYSICAL JOURNAL

IF3.1

2021-06-01

OAAI

Henry, Eric R.; Harper, Julia; Glass, Kristen E.; Metaferia, Belhu; Louis, John M.; Eaton, William A.

Estimating computational limits on theoretical descriptions of biological cells 估算生物细胞理论描述的计算极限

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-01-25

OAAI

Netz, Roland R.; Eaton, William A.

Physics of virus transmission by speaking droplets

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-09-24

OAAI

Netz, Roland R.; Eaton, William A.

Allosteric control of hemoglobin S fiber formation by oxygen and its relation to the pathophysiology of sickle cell disease

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-06-11

OAAI

Henry, Eric R.; Cellmer, Troy; Dunkelberger, Emily B.; Metaferia, Belhu; Hofrichter, James; Li, Quan; Ostrowski, David; Ghirlando, Rodolfo; Louis, John M.; Moutereau, Stephane; Galacteros, Frederic; Thein, Swee Lay; Bartolucci, Pablo; Eaton, William A.

Treating sickle cell anemia

SCIENCE

IF45.8

2020-03-13

OAAI

Tisdale, John F.; Thein, Swee Lay; Eaton, William A.

Hemoglobin S polymerization and sickle cell disease: A retrospective on the occasion of the 70th anniversary of Pauling's Science paper

AMERICAN JOURNAL OF HEMATOLOGY

IF9.9

2019-12-31

OAAI

Eaton, William A.

Interactions of an Anti-Sickling Drug with Hemoglobin in Red Blood Cells from a Patient with Sickle Cell Anemia

BIOCONJUGATE CHEMISTRY

IF3.9

2019-02-22

OAAI

Strader, Michael Brad; Liang, Hongying; Meng, Fantao; Harper, Julia; Ostrowski, David A.; Henry, Eric R.; Shet, Arun S.; Eaton, William A.; Thein, Swee L.; Alayash, Abdu I.

Voxelotor treatment of a patient with sickle cell disease and very severe anemia

AMERICAN JOURNAL OF HEMATOLOGY

IF9.9

2019-01-08

OAAI

Shet, Arun S.; Mendelsohn, Laurel; Harper, Julia; Ostrowski, David; Henry, Eric R.; Gwaabe, Eveline; Nichols, Jim; Alayash, Abdu I.; Eaton, William A.; Thein, Swee Lay

Protein folding transition path times from single molecule FRET

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2018-02-01

103

OAAI

Chung, Hoi Sung; Eaton, William A.

Theory, simulations, and experiments show that proteins fold by multiple pathways

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-10-30

OAAI

Eaton, William A.; Wolynes, Peter G.

Kinetic assay shows that increasing red cell volume could be a treatment for sickle cell disease

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-01-17

OAAI

Li, Quan; Henry, Eric R.; Hofrichter, James; Smith, Jeffrey F.; Cellmer, Troy; Dunkelberger, Emily B.; Metaferia, Belhu B.; Jones-Straehle, Stacy; Boutom, Sarah; Christoph, Garrott W.; Wakefield, Terri H.; Link, Mary E.; Staton, Dwayne; Vass, Erica R.; Miller, Jeffery L.; Hsieh, Matthew M.; Tisdale, John F.; Eaton, William A.

Universality of supersaturation in protein-fiber formation

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2016-03-28

OAAI

Cellmer, Troy; Ferrone, Frank A.; Eaton, William A.

Single Molecule Fluorescence Studies of Transition Paths in DNA Hairpin Folding

BIOPHYSICAL JOURNAL

IF3.1

2016-02-01

OAAI

Truex, Katherine; Chung, Hoi Sung; Louis, John M.; Eaton, William A.

研究方向