Leemor Joshua‐Tor - Publications, H-index & Citations

Leemor Joshua‐Tor

cold spring harbor laboratory

51H指数

176论文数

1.4W被引数

收录论文 55

发表时间

Structural and mechanistic insights into Dis3L2-mediated degradation of structured RNA Dis3L2介导的结构化RNA降解的结构与机制见解

RNA

IF5

2025-12-01

PREAI

Matos, Rute G.; Garg, Ankur; Costa, Susana M.; Pereira, Patricia; Arraiano, Cecilia M.; Joshua-Tor, Leemor; Viegas, Sandra C.

Structural basis of DNA-dependent coactivator recruitment by the tuft cell master regulator POU2F3 POU2F3作为刷状细胞主调控因子，其DNA依赖性的共激活因子募集的结构基础

Cell Reports

IF6.9

2025-11-18

OAAI

Aktan Alpsoy; Jonathan J. Ipsaro; Damianos Skopelitis; Sujay Pal; Frank S. Chung; Shannon Carpenter; John J. Desmarais; Xiaoli S. Wu; Kenneth Chang; Matthew T. DiMare; Erin Harten; Staci Bergman; Justin B. Kinney; Jeffrey A. Engelman; Hyo-Eun C. Bhang; Leemor Joshua-Tor; Christopher R. Vakoc

Repeated emergence of giant microRNA hairpins across invertebrates 无脊椎动物中巨型microRNA发夹结构的反复出现

Cell Reports

IF6.9

2025-09-10

OAAI

Mir-Mammad Javad-zada; Xiaodong Zou; Katsutomo Okamura; Renfu Shang; Ankur Garg; Ethan Lee; Leemor Joshua-Tor; Bastian Fromm; Eric C. Lai

The structural landscape of Microprocessor-mediated processing of pri-let-7 miRNAs

MOLECULAR CELL

IF16.6

2024-11-01

OAAI

Garg, Ankur; Shang, Renfu; Cvetanovic, Todor; Lai, Eric C.; Joshua-Tor, Leemor

SRSF1 interactome determined by proximity labeling reveals direct interaction with spliceosomal RNA helicase DDX23 通过邻近标记确定的SRSF1相互作用组揭示了与剪接体RNA解旋酶DDX23的直接相互作用

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-05-14

OAAI

Segovia, Danilo; Adams, Dexter W.; Hoffman, Nickolas; Tepes, Polona Safaric; Wee, Tse-Luen; Cifani, Paolo; Joshua-Tor, Leemor; Krainer, Adrian R.

Catalytic residues of microRNA Argonautes play a modest role in microRNA star strand destabilization in C. elegans

NUCLEIC ACIDS RESEARCH

IF13.1

2024-03-12

OAAI

Kotagama, Kasuen; Grimme, Acadia L.; Braviner, Leah; Yang, Bing; Sakhawala, Rima M.; Yu, Guoyun; Benner, Lars Kristian; Joshua-Tor, Leemor; Mcjunkin, Katherine

A circadian-like gene network programs the timing and dosage of heterochronic miRNA transcription during C. elegans development 一个类似昼夜节律的基因网络对秀丽隐杆线虫发育过程中异慢性miRNA转录的时间和剂量进行编程

DEVELOPMENTAL CELL

IF8.7

2023-11-01

PREAI

Kinney, Brian; Sahu, Shubham; Stec, Natalia; Hills-Muckey, Kelly; Adams, Dexter W.; Wang, Jing; Jaremko, Matt; Joshua-Tor, Leemor; Keil, Wolfgang; Hammell, Christopher M.

A shape-shifting nuclease unravels structured RNA

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2023-02-23

OAAI

Meze, Katarina; Axhemi, Armend; Thomas, Dennis R.; Doymaz, Ahmet; Joshua-Tor, Leemor

ETV6 dependency in Ewing sarcoma by antagonism of EWS-FLI1-mediated enhancer activation 通过EWS-FLI1-mediated增强子激活的拮抗作用，ETV6对尤文肉瘤的依赖性

NATURE CELL BIOLOGY

IF19.1

2023-01-19

OAAI

Gao, Yuan; He, Xue-Yan; Wu, Xiaoli S.; Huang, Yu-Han; Toneyan, Shushan; Ha, Taehoon; Ipsaro, Jonathan J.; Koo, Peter K.; Joshua-Tor, Leemor; Bailey, Kelly M.; Egeblad, Mikala; Vakoc, Christopher R.

Target binding triggers hierarchical phosphorylation of human Argonaute-2 to promote target release

ELIFE

IF0

2022-05-31

OAAI

Bibel, Brianna; Elkayam, Elad; Silletti, Steve; Komives, Elizabeth A.; Joshua-Tor, Leemor

Developmental roles and molecular mechanisms of Asterix/GTSF1

WILEY INTERDISCIPLINARY REVIEWS-RNA

IF4.8

2022-02-02

OAAI

Ipsaro, Jonathan J.; Joshua-Tor, Leemor

Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons

CELL REPORTS

IF6.9

2021-03-01

OAAI

Ipsaro, Jonathan J.; O'Brien, Paul A.; Bhattacharya, Shibani; Palmer, Arthur G., III; Joshua-Tor, Leemor

Evolution of DNA replication origin specification and gene silencing mechanisms

NATURE COMMUNICATIONS

IF15.7

2020-10-14

OAAI

Hu, Y.; Tareen, A.; Sheu, Y-J.; Ireland, W. T.; Speck, C.; Li, H.; Joshua-Tor, L.; Kinney, J. B.; Stillman, B.

SARS-CoV-2 neutralizing antibody responses are more robust in patients with severe disease 严重疾病患者的SARS-CoV-2中和抗体反应更强烈

EMERGING MICROBES & INFECTIONS

IF7.5

2020-09-25

OAAI

Wang, Pengfei; Liu, Lihong; Nair, Manoj S.; Yin, Michael T.; Luo, Yang; Wang, Qian; Yuan, Ting; Mori, Kanako; Solis, Axel Guzman; Yamashita, Masahiro; Garg, Ankur; Purpura, Lawrence J.; Laracy, Justin C.; Yu, Jian; Joshua-Tor, Leemor; Sodroski, Joseph; Huang, Yaoxing; Ho, David D.

The dynamic nature of the human origin recognition complex revealed through five cryoEM structures

ELIFE

IF0

2020-08-18

OAAI

Jaremko, Matt J.; On, Kin Fan; Thomas, Dennis R.; Stillman, Bruce; Joshua-Tor, Leemor

Mechanisms of Phosphorylation-Mediated Regulation of the RNAi Effector Protein Argonaute 2

FASEB JOURNAL

IF4.2

2020-04-17

OAAI

Bibel, Brianna; Elkayam, Elad; Joshua-Tor, Leemor

Increasing gender diversity in the STEM research workforce

SCIENCE

IF45.8

2019-11-08

PREAI

Greider, Carol W.; Sheltzer, Jason M.; Cantalupo, Nancy C.; Copeland, Wilbert B.; Dasgupta, Nilanjana; Hopkins, Nancy; Jansen, Jaclyn M.; Joshua-Tor, Leemor; McDowell, Gary S.; Metcalf, Jessica L.; McLaughlin, BethAnn; Olivarius, Ann; O'Shea, Erin K.; Raymond, Jennifer L.; Ruebain, David; Steitz, Joan A.; Stillman, Bruce; Tilghman, Shirley M.; Valian, Virginia; Villa-Komaroff, Lydia; Wong, Joyce Y.

High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations 暴发株人诺如病毒外壳的高分辨率cryo-em结构揭示了大小变化

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-06-10

OAAI

Jung, James; Grant, Timothy; Thomas, Dennis R.; Diehnelt, Chris W.; Grigorieff, Nikolaus; Joshua-Tor, Leemor

Decoding the 5′ nucleotide bias of PIWI-interacting RNAs

NATURE COMMUNICATIONS

IF15.7

2019-02-19

OAAI

Stein, Chad B.; Genzor, Pavol; Mitra, Sanga; Elchert, Alexandra R.; Ipsaro, Jonathan J.; Benner, Leif; Sobti, Sushil; Su, Yijun; Hammell, Molly; Joshua-Tor, Leemor; Haase, Astrid D.

ELTA: Enzymatic Labeling of Terminal ADP-Ribose

MOLECULAR CELL

IF16.6

2019-02-01

OAAI

Ando, Yoshinari; Elkayam, Elad; McPherson, Robert Lyle; Dasovich, Morgan; Cheng, Shang-Jung; Voorneveld, Jim; Filippov, Dmitri, V; Ong, Shao-En; Joshua-Tor, Leemor; Leung, Anthony K. L.

研究方向