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A Rewritable, Random-Access DNA-Based Storage System

delete2015-09-18
delete368
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OA
AI
S
S. M. Hossein Tabatabaei Yazdi
Y
Yongbo Yuan
Jian Ma 封面图
Jian Ma (Jian Ma)
赵慧敏 封面图
赵慧敏 (Huimin Zhao)
O
Olgica Milenković *
DOI:10.1038/srep14138delete
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摘要

摘要

En 中文
We describe the first DNA-based storage architecture that enables random access to data blocks and rewriting of information stored at arbitrary locations within the blocks. The newly developed architecture overcomes drawbacks of existing read-only methods that require decoding the whole file in order to read one data fragment. Our system is based on new constrained coding techniques and accompanying DNA editing methods that ensure data reliability, specificity and sensitivity of access, and at the same time provide exceptionally high data storage capacity. As a proof of concept, we encoded parts of the Wikipedia pages of six universities in the USA, and selected and edited parts of the text written in DNA corresponding to three of these schools. The results suggest that DNA is a versatile media suitable for both ultrahigh density archival and rewritable storage applications.
Keyword:
ERROR-CORRECTING CODES
DIGITAL INFORMATION
CONSTRUCTION
DESIGN
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期刊

Scientific Reports 封面图
Scientific Reports
IF:
3.9
论文数:
28.2W
被引数:
83.5W

机构

U
University of Illinois Urbana-Champaign
学者数:
2.4W
论文数: 2.0W
被引数: 35
University of Illinois System 封面图
University of Illinois System
学者数:
6.9W
论文数: 6.2W
被引数: 644
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