A transition tensor for quantifying spatial transcriptome attractors

Nie, Qing

doi:10.1038/s41592-024-02267-w

2024-05-22

PRE

Nie, Qing *

Zhou, Peijie

DOI：10.1038/s41592-024-02267-w

原文链接

摘要

En 中文

Spatial transcriptomics and mRNA splicing measurements encode rich spatiotemporal information for cell states and their transitions. We present a multiscale dynamical system method for reconstructing cell-state-specific dynamics and spatial state transitions. This theory-based approach reconciles short-timescale local tensor streamlines between cells with long-timescale transition paths that connect cell attractors.

期刊

Nature Methods

IF:

32.1

论文数:

7.3K

被引数:

12.7W

机构

University of California System

学者数:

37.7W

论文数: 33.8W

被引数: 6.6K

University of California Irvine

学者数:

318

论文数: 138

被引数: 0

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