Advances in Spatial Omics Technologies

Hui, Tianxiao

doi:10.1002/smtd.202401171

2025-03-18

PRE

DOI：10.1002/smtd.202401171

原文链接

原文求助

摘要

En 中文

快速发展中的空间组学技术为我们提供了深入了解生物体内细胞类型多样性和功能的新方法。与传统的技术方法不同，空间组学技术使研究人员能够在细胞甚至亚细胞水平上解析组织结构与功能之间的复杂关系。空间组学技术的应用为诸如神经系统发育、器官发育和肿瘤微环境等关键生物学过程提供了新的视角。本综述聚焦于空间组学技术的进展和策略，总结其在生物医学研究中的应用，并强调了空间组学技术在推动发育和疾病相关生命科学理解方面的重要作用。

Keyword:

cancer biology

developmental biology

neurobiology

spatial omics

spatial transcriptomics

期刊

Small Methods

IF:

9.1

论文数:

4.3K

被引数:

2.2W

机构

暂无机构信息

引用论文

Toward Understanding the Subcellular Distributions of Cholesterol and Sphingolipids Using High-Resolution NanoSIMS Imaging

ACCOUNTS OF CHEMICAL RESEARCH

IF17.7

2023-03-13

PREAI

Brunet, Melanie A.; Kraft, Mary L.

Deep Profiling of Mouse Splenic Architecture with CODEX Multiplexed Imaging 使用CODEX多路成像对小鼠脾脏结构进行深度分析

Cell

IF0

2018-08-01

OAAI

Yury Goltsev; Nikolay Samusik; Julia Kennedy-Darling; Salil Bhate; Matthew Hale; Gustavo Vazquez; Sarah Black; Garry P. Nolan

Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex 人背外侧前额叶皮层中转录组尺度的空间基因表达

Nature Neuroscience

IF0

2021-02-08

OAAI

Kristen R. Maynard; Leonardo Collado-Torres; Lukas M. Weber; Cedric Uytingco; Brianna K. Barry; Stephen R. Williams; Joseph L. Catallini; Matthew N. Tran; Zachary Besich; Madhavi Tippani; Jennifer Chew; Yifeng Yin; Joel E. Kleinman; Thomas M. Hyde; Nikhil Rao; Stephanie C. Hicks; Keri Martinowich; Andrew E. Jaffe

Molecular and cellular mechanisms of selective vulnerability in neurodegenerative diseases

NATURE REVIEWS NEUROSCIENCE

IF26.7

2024-04-04

PREAI

Kampmann, Martin

Identification of early neurodegenerative pathways in progressive multiple sclerosis

Nature Neuroscience

IF0

2022-06-20

OAAI

Max Kaufmann; Anna-Lena Schaupp; Rosa Sun; Fabian Coscia; Calliope A. Dendrou; Adrian Cortes; Gurman Kaur; Hayley G. Evans; Annelie Mollbrink; José Fernández Navarro; Jana K. Sonner; Christina Mayer; Gabriele C. DeLuca; Joakim Lundeberg; Paul M. Matthews; Kathrine E. Attfield; Manuel A. Friese; Matthias Mann; Lars Fugger

Cerebellar nuclei evolved by repeatedly duplicating a conserved cell-type set

Science

IF0

2020-12-18

OAAI

Justus M. Kebschull; Ethan B. Richman; Noam Ringach; Drew Friedmann; Eddy Albarran; Sai Saroja Kolluru; Robert C. Jones; William E. Allen; Ying Wang; Seung Woo Cho; Huaijun Zhou; Jun B. Ding; Howard Y. Chang; Karl Deisseroth; Stephen R. Quake; Liqun Luo

Atlas of Subcellular RNA Localization Revealed by APEX-Seq Apex-seq揭示的亚细胞RNA定位图谱

Cell

IF0

2019-07-01

OAAI

Furqan M. Fazal; Shuo Han; Kevin R. Parker; Pornchai Kaewsapsak; Jin Xu; Alistair N. Boettiger; Howard Y. Chang; Alice Y. Ting

High-depth spatial transcriptome analysis by photo-isolation chemistry

NATURE COMMUNICATIONS

IF15.7

2021-07-20

OAAI

Honda, Mizuki; Oki, Shinya; Kimura, Ryuichi; Harada, Akihito; Maehara, Kazumitsu; Tanaka, Kaori; Meno, Chikara; Ohkawa, Yasuyuki