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Advancing insect research through cell line transcriptomics

delete2026-02-01
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PRE
AI
S
Surjeet Kumar Arya *
S
Subba Reddy Palli
C
Cynthia L. Goodman
DOI:10.1007/s11626-026-01155-1delete
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摘要

摘要

En 中文
本综述强调了昆虫细胞系在转录组学研究中的重要性,突出了它们作为揭示昆虫生理学、免疫反应和环境胁迫适应性的细胞和分子机制的关键工具的作用。来自中肠、脂肪体、神经系统和生殖器官等组织的细胞系使研究人员能够在受控环境中检查基因表达变化,从而获得难以通过全生物体研究实现的发现。高通量测序和单细胞RNA测序(scRNA-seq)已鉴定出与解毒、应激反应、发育和免疫防御相关的基因,为未来在农业、害虫控制和生物技术中的应用提供了有价值的见解。为了清晰组织这些信息,我们已在表格中总结了关键发现,提供了每种细胞系在转录组学研究中的重要作用的便捷概述。这种方法不仅强调了昆虫细胞系在功能基因组学中的适应性,还突出了它们作为害虫管理、病毒学和生物工程模型系统的实用性。通过利用转录组学,昆虫细胞系继续加深我们对昆虫生物学的理解,并促进可持续作物保护和生物技术应用的创新策略的发展。
Keyword:
Insect cell lines
Transcriptomics
ScRNA-seq
Functional genomics
High-throughput sequencing
Sustainable agriculture

期刊

I
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
IF:
1.7
论文数:
84
被引数:
0

机构

U
University of Kentucky
学者数:
2.5W
论文数: 2.1W
被引数: 41
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