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Biology Direct 封面图

Biology Direct

IF4.9
论文数1381
被引数2704
期刊论文 1381
发表时间
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Beyond oncogenesis: how pathogen-induced immune remodeling shapes tumor immune escape and immunotherapy resistance超越肿瘤发生：病原体诱导的免疫重塑如何塑造肿瘤免疫逃逸和免疫治疗耐药性
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delete2026-11-03
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deleteYuefan Zhang; Yue Shu; Lizhou Song; Lindong Cheng; Chenglong Zhu; Yan Liao; Haoling Zhang; Wangzheqi Zhang; Peng Luo; Zui Zou
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Egr1-mediated transcription of LRRC1 impairs endometrial receptivity in recurrent implantation failure by disrupting PP1A–YAP interactionEgr1介导的LRRC1转录通过破坏PP1A–YAP相互作用损害反复着床失败中的子宫内膜容受性
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delete2026-10-27
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deleteLingling Huang; Liping Zou; Bin Yang; Ruiyin Jiang; Zixing Chen; Chaoyi Xiong; Yanqing Deng; Zengming Li; Yan Zhao; Jiaying Lin; Jialyu Huang
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P300-mediated H3K27 acetylation activates the TRAF3IP3/ERK axis to promote glioblastoma progressionP300介导的H3K27乙酰化通过激活TRAF3IP3/ERK轴促进胶质母细胞瘤进展
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deleteQi Lin; Peng Yu; ZhengYu Zhang; XianZhen Chen; Jia Yin
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Mitochondrial transfer and transplantation in cardiovascular diseases: from signaling pathways to targeted delivery strategies线粒体转移和移植在心血管疾病中的应用：从信号通路到靶向递送策略
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deleteYao Xie; Yue Liu; Shasha Xing
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Blue light induces autophagy imbalance and DNA damage repair disorders in keratinocytes by inhibiting the PI3K/AKT signaling pathway through ITGB3蓝光通过ITGB3抑制PI3K/AKT信号通路诱导角质形成细胞自噬失衡和DNA损伤修复障碍
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IF4.9
delete2026-10-26
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deleteYing Tu; Zhenghui Yang; Xin Zhang; Yaqi Yang; Li He; Hua Gu
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DCAF13 promotes hepatocellular carcinoma progression by mediating RCAN1.4 ubiquitination and activating calcineurin/NFAT1 signalingDCAF13通过介导RCAN1.4泛素化和激活钙调磷酸酶/NFAT1信号通路促进肝细胞癌进展
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IF4.9
delete2026-10-24
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deleteFangzhe Tan; Xiongwen Shi; Hongxin Lang; Xiaohang Li
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Integrative transcriptomic and single-cell analyses link ENO1 to CD4+ T cell function and glycolysis-associated metabolism in systemic lupus erythematosus整合转录组学和单细胞分析将ENO1与系统性红斑狼疮中CD4+ T细胞功能及糖酵解相关代谢联系起来
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deleteWan Dong; Zhanchuan Ma; Yanjie Jia; Donglei Ji; Lei Zeng; Huanfa Yi
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HSP90B1 exacerbates myocardial infarction injury by promoting cardiomyocyte pyroptosis and is associated with M1-like macrophage polarizationHSP90B1通过促进心肌细胞焦亡加剧心肌梗死损伤，并与M1型巨噬细胞极化相关
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delete2026-10-22
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deleteYemin Wang; Jiaqian Ge; Ying Zhang; Keke Shi; Jianrong Bao; Mingxiu Dai; Xiaopeng Zhang; Xuexue Liu; Jiaqian Lin; Zilong Tang; Lei Sun; Xiao Yu
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Metabolism-related post-translational modifications in nucleus pulposus cells during intervertebral disc degeneration椎间盘退变过程中髓核细胞的代谢相关翻译后修饰
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deleteLeyi Zhao; Lei An; Yuxing Ye; Junming Liang; Shaobo Wu; Dageng Huang
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A non-metabolic function of hexokinase 2 in colorectal cancer: HK2 promotes malignant phenotypes by facilitating UBE3A-Dependent ZNF366 degradation己糖激酶2在结直肠癌中的非代谢功能：HK2通过促进UBE3A依赖性ZNF366降解来促进恶性表型
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delete2026-10-22
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deleteZhen Jia; Xinlong Liu; Li Zhao; Hanbing Wang; Yihang Liu; Shuang Liu; Mei Jia; Bingqian Heng; Jiaxu Fan; Yabin Liu; Peng Kong; Dexian Kong
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VCAM-1 promotes colorectal cancer progression and metastasis via the RhoA/LIMK/Cofilin pathwayVCAM-1通过RhoA/LIMK/Coilin通路促进结直肠癌进展和转移
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deleteQian Zhang; Abuduweili Wufuer; Zanlin Li; Tao Hong; Zhi Wang
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Integrated analysis and validation of oxidative stress-related genes in renal ischemia-reperfusion injury氧化应激相关基因在肾缺血再灌注损伤中的综合分析与验证
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delete2026-10-21
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deleteMengxia Shi; Bicheng Li; Han Zhu; Rui Zeng; Ying Yao
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Rapid turnover of sex chromosomes is associated with speciation in Neotropical armored catfish Harttia (Siluriformes, Loricariidae)新热带区甲鲶科鱼类Harttia（鲇形目，甲鲶科）中性别染色体的快速周转与物种形成相关
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deleteFrancisco de Menezes Cavalcante Sassi; Fernando Henrique Santos de Souza; Manolo Fernandez Perez; Foyez Shams; Tariq Ezaz; Geize Aparecida Deon; Thomas Liehr; Luohao Xu; Marcelo de Bello Cioffi
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CRISPR–Cas diversity in Microcoleus genomes reveals a dynamic history of gene flow and mobile genetic element interactions微coleus基因组中的CRISPR–Cas多样性揭示了基因流和可移动遗传元件相互作用的历史动态
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deleteBarbora Hájková; Aleksandar Stanojković; Svatopluk Skoupý; Petr Dvořák
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Insufficient BMP8B–SULF2 signaling may contribute to preeclampsia by impairing extravillous trophoblast functionBMP8B–SULF2信号不足可能通过损害绒毛外滋养层细胞功能导致子痫前期
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delete2026-10-16
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deleteYue Liang; Zirui Peng; Zhuoqun Ren; Kejie Wu; Yan Li; Yanli Ban; Jinlai Meng; Junhao Yan
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Periplocin suppresses osteosarcoma progression by triggering necroptosis and pyroptosis through the “4EBP1-eIF4E” pathwayPeriplocin通过触发“4EBP1-eIF4E”通路介导的坏死性凋亡和焦亡抑制骨肉瘤进展
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deleteJianwei Sun; Shenghong Xu; Qi Liu; Juan Yang; Yan Yang; Shouyan Hao; Yongjie Cheng; Li Ding
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Systematic analysis reveals that KCNH8 suppresses triple-negative breast cancer progression through PI3K‑AKT inhibition系统性分析揭示KCNH8通过抑制PI3K‑AKT通路抑制三阴性乳腺癌进展
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deleteYu-Tong Wang; Yong-Zi Chen; Jing-Jing Shi; Xi-Rui Zhou; Yang Ou; Hong Liu; Hai-Xin Li; Jun Zhang
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CISD2 knockdown suppresses gastric cancer progression and induces ferroptosis associated with mTOR/SREBF1/SCD1 axis inhibition and GPX4 downregulationCISD2敲低抑制胃癌进展并诱导铁死亡，与mTOR/SREBF1/SCD1轴抑制和GPX4下调相关
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delete2026-10-15
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deleteWenxin Zheng; Yue Cai; Tonghan Chang; Yuqing Niu; Feng Li; Biyun Zhang
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Comprehensive multi-omics analysis reveals a robust transcriptomic signature for biochemical recurrence prediction and identifies SPAG5 as a targetable oncogene with small-molecule compounds in prostate cancer多组学综合分析揭示了一种预测生化复发的稳健转录组特征，并鉴定出SPAG5是前列腺癌中可靶向的小分子化合物作用的癌基因
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delete2026-10-14
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deleteXianzi Zeng; Minjia Pan; Qiuqiu Qiu; Yaying Hong; Jiawei Zhou; Yangshu Zhou; Baiheng Zhu; Zichun Zeng; Mingkun Chen; Shan-Chao Zhao; Jinpeng Cen
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Redox imbalance in urology: mechanistic insights into the development and progression of selected urological conditions泌尿外科中的氧化还原失衡：对特定泌尿外科疾病发生和进展的机制性见解
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deleteNadine Gelbrich; Matthias B. Stope
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