Avoiding bias in fluorescence sensor readout

doi:10.1038/s41583-023-00768-9

2023-11-10

PRE

Dmitri A. Rusakov *

DOI：10.1038/s41583-023-00768-9

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摘要

En 中文

荧光指示剂可以提供对大脑回路释放的信号分子的时空动态的定量见解。然而，实验背景和实验成像设置之间的不匹配通常会在此类测量中引入意外的误差和偏差。理解这种不匹配应该有助于研究人员得出无偏的估计。荧光指示剂可以提供对大脑回路释放的信号分子的时空动态的定量见解。然而，实验背景和实验成像设置之间的不匹配通常会在此类测量中引入意外的误差和偏差。认识到这种不匹配应该有助于得出无偏的估计。

期刊

Nature Reviews Neuroscience

IF:

26.7

论文数:

4.0K

被引数:

4.8W

机构

university of london

学者数:

21.5W

论文数: 19.7W

被引数: 305

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