Chloroplast thylakoids reduce glucose uptake and decrease intestinal macromolecular permeability

Caroline Montelius

doi:10.1017/S0007114511001267

2011-05-11

Charlotte Erlanson‐Albertsson *

DOI：10.1017/S0007114511001267

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摘要

En 中文

Thylakoid membranes, derived from chloroplasts, have previously been shown to retard fat digestion and lower blood glucose levels after oral intake. The purpose of the present study was to investigate the effect of thylakoid membranes on the passage of methyl-glucose, dextran and ovalbumin over rat intestine in vitro using Ussing chambers. The results show that thylakoids retard the passage of each of the test molecules in a dose-dependent way. The thylakoids appear to be attached on the mucosal surface and a mechanism is suggested that the thylakoids delay the passage of the test molecules by sterical hindrance. The present results indicate that thylakoid membranes may be useful both to control intestinal absorption of glucose and to enhance the barrier function of the intestine.

Keyword:

Membranes

Hyperglycaemia

Barrier function

Fatty acids

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期刊

British Journal of Nutrition

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论文数:

1.0W

被引数:

3.0W

机构

Lund University

学者数:

1.7K

论文数: 668

被引数: 1

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