Controlling gene expression using AI designed Cis-regulatory elements

Yan Xia

doi:10.1016/j.biotechadv.2026.108802

2026-01-18

PRE

Yan Xia

Yi-xin HUO *

DOI：10.1016/j.biotechadv.2026.108802

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摘要

En 中文

• Deep generative models enable de novo design of cis-regulatory elements. • DNA foundation models extend regulatory modeling to long genomic contexts and support genome-scale generation.YH182. • Multimodal modeling, reinforcement learning, and system-level network design can further advance genomic regulation.

期刊

Biotechnology Advances

IF:

12.5

论文数:

3.0K

被引数:

2.7W

机构

Beijing Institute of Technology

学者数:

5.2K

论文数: 2.1K

被引数: 6.0W

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