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Nature Biotechnology 封面图

Nature Biotechnology

IF41.7
论文数12368
被引数100514
期刊论文 12368
发表时间
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An mRNA–lipid nanoparticle vaccine against H5N1 influenza virus protects lactating dairy cows from infectionH5N1流感病毒的mRNA-脂质纳米颗粒疫苗保护泌乳奶牛免受感染
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IF41.7
delete2026-10-28
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deleteJefferson J. S. Santos; Carine K. Souza; Giovana C. Zanella; Débora B. Goulart; Bailey Arruda; Paola Boggiatto; Mitchell V. Palmer; Celeste A. Snyder; Michaela A. Kristula; Charlene Dickens; Terry L. Webb; Reilly K. Atkinson; Bernadeta Dadonaite; Garima Dwivedi; Mohamad-Gabriel Alameh; Christopher A. Hunter; Lisa A. Murphy; Jesse D. Bloom; Drew Weissman; Gary C. Althouse; Amy L. Baker; Scott E. Hensley
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An engineered, compact Cas12m variant for multiplexed gene activation in vivo一种经过工程改造的紧凑型Cas12m变体，用于体内多重基因激活
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IF41.7
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deleteHainan Zhang; Lin Yang; Yuling Liu; Dingyi Han; Yingnan Li; Jiajia Lin; Bingyan Wang; Jiaxu Hu; Yaru Zhang; Yi Zhang; Jinhui Li; Shuping Wei; Simiao Liu; Tong Li; Na Zhong; Ganggang Zhang; Xingtao Zhou; Linyu Shi; Jinhai Huang; Hui Yang; Guohe Tan; Yingsi Zhou; Guoling Li
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Giving AI a seat at the peer review table给人工智能一个同行评审的席位
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IF41.7
delete2026-10-26
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deleteKonstantinos Drosatos; Aristotelis Tsirigos
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Deep dynamical models of single-cell multiomic velocities predict loss-of-function and rescue perturbations in B cells单细胞多组学速度的深度动力学模型预测B细胞中的功能丧失和拯救扰动
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IF41.7
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deleteAlireza Karbalayghareh; Benedikt Pelzer; Christopher R. Chin; Ari Melnick; Darko Barisic; Christina S. Leslie
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Recordanelles for transcriptome-wide single-cell RNA recording in human cells用于人类细胞转录组范围单细胞RNA记录的记录anelles
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deleteChristopher D. Reinkemeier; Marcos Manero-Carranza; Rick Farouni; Federica Filice; Alexander Klotz; Konstantin Schneider-Heieck; Tim L. Andermann; Randall J. Platt
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Genetic code expansion enables plant-directed control of bacterial activity遗传密码扩展实现植物对细菌活性的定向控制
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deleteVivian Zhong; Michaela A. Jones; Avaniek Cabales; Alice Gevorgyan; René Inckemann; Anna A. Johnson; Sumudu S. Karunadasa; Amanda M. Forti; Shou-Ling Xu; Aditya M. Kunjapur; Jennifer A. N. Brophy
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Engineered human Argonaute 2 for targeted C-to-U RNA base editing工程化人Argonaute 2用于靶向C到U的RNA碱基编辑
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IF41.7
delete2026-10-20
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deleteRobert F. Lusi; Salvador Moncayo von Hase; Corey Model; Steven M. Banik
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Editor’s pick: Bioptimus编辑精选：Bioptimus
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IF41.7
delete2026-10-19
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deleteMichael Eisenstein
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Structural variant detection across sequencing technologies测序技术中的结构变异检测
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IF41.7
delete2026-10-15
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deleteGaoyang Li; Yadong Liu; Anqi Zhang; Xiaoyi Lin; Zheng Hu; Bo Liu; Long Qian; Yadong Wang
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Proteomic aging clocks go to trial蛋白质组学衰老时钟进入临床试验
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delete2026-10-13
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deleteNeil A. Robertson; Tamir Chandra
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In vivo engineering of CAR natural killer cells for immunotherapy using ligand-directed lipid nanoparticles体内工程化CAR自然杀伤细胞用于免疫治疗的配体定向脂质纳米颗粒
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deleteYuang Chen; Julia Monkovic; Haseeb Mughal; Binlong Chen; Elina Thadhani; Patrick McMullen; Ava Self; Yuxuan Chen; Yizong Hu; Samuel Detmer; Min Chen; Anna Lapteva; Ria Kamat; Ashley Vernon; Robert Langer; Daniel G. Anderson
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Regeneron approval brings relief for ‘second skeleton’ bone disorder再生元获批为“第二骨骼”骨紊乱带来缓解
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deleteLaura DeFrancesco
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Expanding global access to synthetic biology扩展全球对合成生物学的获取途径
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deletePrakriti Karki; Sudarshan GC
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Five questions with Bowen Li与李 Bowen 的五个问题
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deleteMichael Francisco
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Engrafting human cortical organoids移植人类皮质类器官
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deleteDario Ummarino
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The global patent landscape of CRISPR–Cas applications in medicineCRISPR–Cas技术在医学应用中的全球专利格局
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deleteYunfang Yu; Yan Zhang; Yanjun Xu; Cai Wen; Li Li; Tao Yu
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Live-cell imaging goes WHOLISTIC活细胞成像走向整体化
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deleteDario Ummarino
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Tracing the origins of CRISPR–Cas追溯CRISPR–Cas的起源
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deleteDario Ummarino
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Shotgun engineering fires up mammalian metabolic design组学工程为哺乳动物代谢设计注入活力
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delete2026-10-06
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deleteKshitij Rai; Caleb J. Bashor
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Highly multiplexed mammalian metabolic engineering with a shotgun approach高通量哺乳动物代谢工程的多重构建策略
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deleteJulie Trolle; Sofia Sessa; Aleksandra Wudzinska; Mark Grivainis; Katerina Rincones; Tori Rodrick; Drew R. Jones; David Fenyö; Sudarshan Pinglay; Jef D. Boeke
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