Curing CLL: one clone at a time

doi:10.1182/bloodadvances.2022009177

2023-05-09

Burcu Aslan *

Shady I. Tantawy

Varsha Gandhi

DOI：10.1182/bloodadvances.2022009177

原文链接

查看原文

摘要

Keyword:

IBRUTINIB

AI总结

对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。

期刊

Blood Advances

IF:

7.1

论文数:

6.1K

被引数:

2.3W

机构

university of texas system

学者数:

18.5W

论文数: 15.6W

被引数: 210

引用论文

BTK gatekeeper residue variation combined with cysteine 481 substitution causes super-resistance to irreversible inhibitors acalabrutinib, ibrutinib and zanubrutinib

LEUKEMIA

IF13.4

2021-02-01

OAAI

Estupinan, H. Yesid; Wang, Qing; Berglof, Anna; Schaafsma, Gerard C. P.; Shi, Yuye; Zhou, Litao; Mohammad, Dara K.; Yu, Liang; Vihinen, Mauno; Zain, Rula; Smith, C. I. Edvard

Ibrutinib and Venetoclax for First-Line Treatment of CLL

NEW ENGLAND JOURNAL OF MEDICINE

IF78.5

2019-05-30

408

OAAI

Jain, Nitin; Keating, Michael; Thompson, Philip; Ferrajoli, Alessandra; Burger, Jan; Borthakur, Gautam; Takahashi, Koichi; Estrov, Zeev; Fowler, Nathan; Kadia, Tapan; Konopleva, Marina; Alvarado, Yesid; Yilmaz, Musa; DiNardo, Courtney; Bose, Prithviraj; Ohanian, Maro; Pemmaraju, Naveen; Jabbour, Elias; Sasaki, Koji; Kanagal-Shamanna, Rashmi; Patel, Keyur; Jorgensen, Jeffrey; Garg, Naveen; Wang, Xuemei; Sondermann, Katrina; Cruz, Nichole; Wei, Chongjuan; Ayala, Ana; Plunkett, William; Kantarjian, Hagop; Gandhi, Varsha; Wierda, William

NASA ultra low noise X-band microwave feeds for deep space communication

15th International Conference on Microwaves, Radar and Wireless Communications (IEEE Cat. No.04EX824)

IF0

2024-09-03

PREAI

F. Manshadi

Pirtobrutinib inhibits wild-type and mutant Bruton's tyrosine kinase-mediated signaling in chronic lymphocytic leukemia

BLOOD CANCER JOURNAL

IF11.6

2022-05-20

OAAI

Aslan, Burcu; Kismali, Gorkem; Iles, Lakesla R.; Manyam, Ganiraju C.; Ayres, Mary L.; Chen, Lisa S.; Gagea, Mihai; Bertilaccio, Maria Teresa Sabrina; Wierda, William G.; Gandhi, Varsha

Ibrutinib as Initial Therapy for Patients with Chronic Lymphocytic Leukemia

NEW ENGLAND JOURNAL OF MEDICINE

IF78.5

2015-12-17

1.3K

OAAI

Burger, J. A.; Tedeschi, A.; Barr, P. M.; Robak, T.; Owen, C.; Ghia, P.; Bairey, O.; Hillmen, P.; Bartlett, N. L.; Li, J.; Simpson, D.; Grosicki, S.; Devereux, S.; McCarthy, H.; Coutre, S.; Quach, H.; Gaidano, G.; Maslyak, Z.; Stevens, D. A.; Janssens, A.; Offner, F.; Mayer, J.; O'Dwyer, M.; Hellmann, A.; Schuh, A.; Siddiqi, T.; Polliack, A.; Tam, C. S.; Suri, D.; Cheng, M.; Clow, F.; Styles, L.; James, D. F.; Kipps, T. J.; Keating, Michael; Jen, Jie; Jindra, Pavel; Simkovic, Martin; Braester, Andrei; Ruchlemer, Rosa; Foa, Roberto; Semenzato, Gianpietro; Hawkins, Timothy; Atanasio, Carolina Moreno; Demirkan, Fatih; Kaynar, Leylagul; Pylypenko, Halyna; Fox, Christopher; Thirman, Michael; Campbell, Philip; Coughlin, Paul; Harrup, Rosemary; Kuss, Bryone; Turner, Paul; Wu, Ka Lung; Larratt, Loree; Fineman, Riva; Marasca, Roberto; Zinzani, Pier Luigi; Corbett, Gillian; Abrisqueta, Pau; Delgado, Julio; Gonzalez-Barca, Eva; de Oteyza, Jaime Perez; Arsland, Onder; Kaplan, Polina; Oliynyk, Hanna; Hamblin, Michael; Atkins, James; Barrientos, Jaqueline; Gasic, Slavisa; Hou, Jing-Zhou; Kingsley, Edwin; Shadman, Mazyar; Badoux, Xavier; Gill, Devinder; Opat, Stephen; Bron, Dominique; Van Den Neste, Eric; Jing, Hongmei; Zhu, Jun; Vandenberghe, Elisabeth; Tadmor, Tamar; Cortelezzi, Agostino; Ganly, Peter; Weinkove, Robert; Pluta, Andrzej; Pristupa, Alexander; Marco, Jose Antonio Garcia; Vural, Filiz; Yagci, Munci; Kasych, Muzhdaba; Duncombe, Andrew; Fegan, Christopher; Quackenbush, Robert; Tirumali, Nagendra

Ibrutinib combinations in CLL therapy: scientific rationale and clinical results

BLOOD CANCER JOURNAL

IF11.6

2021-04-29

OAAI

Timofeeva, Natalia; Gandhi, Varsha

Application of Spatial Econometric Model in Provincial R & D and Innovation

IF0

PREAI

Ibrutinib versus Ofatumumab in Previously Treated Chronic Lymphoid Leukemia

NEW ENGLAND JOURNAL OF MEDICINE

IF78.5

2014-07-17

1.4K

OAAI

Byrd, J. C.; Brown, J. R.; O'Brien, S.; Barrientos, J. C.; Kay, N. E.; Reddy, N. M.; Coutre, S.; Tam, C. S.; Mulligan, S. P.; Jaeger, U.; Devereux, S.; Barr, P. M.; Furman, R. R.; Kipps, T. J.; Cymbalista, F.; Pocock, C.; Thornton, P.; Caligaris-Cappio, F.; Robak, T.; Delgado, J.; Schuster, S. J.; Montillo, M.; Schuh, A.; de Vos, S.; Gill, D.; Bloor, A.; Dearden, C.; Moreno, C.; Jones, J. J.; Chu, A. D.; Fardis, M.; McGreivy, J.; Clow, F.; James, D. F.; Hillmen, P.

Pirtobrutinib targets BTK C481S in ibrutinib-resistant CLL but second-site BTK mutations lead to resistance

BLOOD ADVANCES

IF7.1

2023-05-09

OAAI

Naeem, Aishath; Utro, Filippo; Wang, Qing; Cha, Justin; Vihinen, Mauno; Martindale, Stephen; Zhou, Yinglu; Ren, Yue; Tyekucheva, Svitlana; Kim, Annette S.; Fernandes, Stacey M.; Saksena, Gordon; Rhrissorrakrai, Kahn; Levovitz, Chaya; Danysh, Brian P.; Slowik, Kara; Jacobs, Raquel A.; Davids, Matthew S.; Lederer, James A.; Zain, Rula; Smith, C. I. Edvard; Leshchiner, Ignaty; Parida, Laxmi; Getz, Gad; Brown, Jennifer R.

Mechanisms of Resistance to Noncovalent Bruton's Tyrosine Kinase Inhibitors

NEW ENGLAND JOURNAL OF MEDICINE

IF78.5

2022-02-24

144

OAAI

Wang, Eric; Mi, Xiaoli; Thompson, Meghan C.; Montoya, Skye; Notti, Ryan Q.; Afaghani, Jumana; Durham, Benjamin H.; Penson, Alex; Witkowski, Matthew T.; Lu, Sydney X.; Bourcier, Jessie; Hogg, Simon J.; Erickson, Caroline; Cui, Dan; Cho, Hana; Singer, Michael; Totiger, Tulasigeri M.; Chaudhry, Sana; Geyer, Mark; Alencar, Alvaro; Linley, Adam J.; Palomba, M. Lia; Coombs, Catherine C.; Park, Jae H.; Zelenetz, Andrew; Roeker, Lindsey; Rosendahl, Mary; Tsai, Donald E.; Ebata, Kevin; Brandhuber, Barbara; Hyman, David M.; Aifantis, Iannis; Mato, Anthony; Taylor, Justin; Abdel-Wahab, Omar

没有更多内容